Lennart Sielmann
@sielmann.bsky.social
PhD student @CeBiTec @Uni Bielefeld, Germany.
Workgroup "Genetics and Genomics of Plants"
Workgroup "Genetics and Genomics of Plants"
Happy to share a new paper by the Computational Biology group from Bielefeld University and myself!🌾🧪🧬🖥
#PlantScience
academic.oup.com/biomethods/a...
#PlantScience
academic.oup.com/biomethods/a...
Optimized DNA affinity purification sequencing determines relative binding affinity of transcription factors
Abstract. DAP-seq is an in vitro method to analyze the relative binding affinity of transcription factors to DNA. It is a fast and scalable method and its
academic.oup.com
November 21, 2025 at 7:46 PM
Happy to share a new paper by the Computational Biology group from Bielefeld University and myself!🌾🧪🧬🖥
#PlantScience
academic.oup.com/biomethods/a...
#PlantScience
academic.oup.com/biomethods/a...
Reposted by Lennart Sielmann
🚨 Seeking a brilliant postdoc for a Marie Skłodowska-Curie Fellowship! Work at the interface of bioinformatics, evolution & biotech.
🌱 Join a top German university
💡 Great science, strong mentoring
👉 www.izmb.uni-bonn.de/en/pbb/contact
#MSCA #Postdoc #Biotech #Bioinformatics #AcademicJobs
🌱 Join a top German university
💡 Great science, strong mentoring
👉 www.izmb.uni-bonn.de/en/pbb/contact
#MSCA #Postdoc #Biotech #Bioinformatics #AcademicJobs
July 7, 2025 at 3:59 AM
Reposted by Lennart Sielmann
Happy to share the results of a project with colleagues at CeBiTec & Bielefeld University:
"Metabolic fingerprinting reveals roles of Arabidopsis thaliana BGLU1, BGLU3 and BGLU4 in glycosylation of various flavonoids"
doi.org/10.1101/2024...
"Metabolic fingerprinting reveals roles of Arabidopsis thaliana BGLU1, BGLU3 and BGLU4 in glycosylation of various flavonoids"
doi.org/10.1101/2024...
February 1, 2024 at 6:51 AM
Happy to share the results of a project with colleagues at CeBiTec & Bielefeld University:
"Metabolic fingerprinting reveals roles of Arabidopsis thaliana BGLU1, BGLU3 and BGLU4 in glycosylation of various flavonoids"
doi.org/10.1101/2024...
"Metabolic fingerprinting reveals roles of Arabidopsis thaliana BGLU1, BGLU3 and BGLU4 in glycosylation of various flavonoids"
doi.org/10.1101/2024...
I'm happy to share our new preprint which focusses on the glycosyltransferases BGLU1, BGLU3 and BGLU4 from Arabidopsis thaliana: www.biorxiv.org/content/10.1...
#PlantScience
🌾🧪
#PlantScience
🌾🧪
Metabolic fingerprinting reveals roles of Arabidopsis thaliana BGLU1, BGLU3 and BGLU4 in glycosylati...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
February 1, 2024 at 2:49 PM
I'm happy to share our new preprint which focusses on the glycosyltransferases BGLU1, BGLU3 and BGLU4 from Arabidopsis thaliana: www.biorxiv.org/content/10.1...
#PlantScience
🌾🧪
#PlantScience
🌾🧪
Wissenschaftliche*r Mitarbeiter*in (m/w/d) (Doktorand*in)
uni-bielefeld.hr4you.org
December 7, 2023 at 7:45 AM
🧬🖥
Our prepring about comparative gene regulatory network analysis is available on bioRxiv! We focused on the regulation of C4 and C3 photosynthesis and identified conserved regulators for other pathways too. www.biorxiv.org/content/10.1... #Bioinformatics #generegulation #photosyntheis #PlantScience
Comparative analysis of gene regulatory networks identifies conserved regulators in seed plants
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
November 25, 2023 at 10:10 AM
🧬🖥
Reposted by Lennart Sielmann
Very happy that our Chlamydomonas manuscript is out. We used RNA-seq and DAP-seq to investigate several CLiP insertion mutants predicted by gene regulatory network inference.
Multiple transcription factors mediate acclimation of Chlamydomonas to light stress https://www.biorxiv.org/content/10.1101/2023.10.30.564712v1
Multiple transcription factors mediate acclimation of Chlamydomonas to light stress https://www.biorxiv.org/content/10.1101/2023.10.30.564712v1
Light as a substrate for photosynthesis may be a boon or a bane. To thrive, photosynthetic organisms
www.biorxiv.org
October 31, 2023 at 12:38 PM
Very happy that our Chlamydomonas manuscript is out. We used RNA-seq and DAP-seq to investigate several CLiP insertion mutants predicted by gene regulatory network inference.
Reposted by Lennart Sielmann
Beautiful new cover of the latest Issue of Trends in #PlantScience
October 3, 2023 at 6:51 AM
Beautiful new cover of the latest Issue of Trends in #PlantScience
Reposted by Lennart Sielmann
Interested the history of the Nobel-winning work that led to mRNA vaccines? Read the story in this new book
cshlpress.com/default.tpl?...
cshlpress.com/default.tpl?...
October 2, 2023 at 2:52 PM
Interested the history of the Nobel-winning work that led to mRNA vaccines? Read the story in this new book
cshlpress.com/default.tpl?...
cshlpress.com/default.tpl?...
Just tried out NextDenovo (https://github.com/Nextomics/NextDenovo/) for an Arabidopsis genome assembly and I am really pleased with the outcome! The assembly looks great so far and the run time was really short. Anyone doing genome assemblies should definitely give this tool a try! 🧪🧬🖥️
GitHub - Nextomics/NextDenovo: Fast and accurate de novo assembler for long reads
Fast and accurate de novo assembler for long reads - GitHub - Nextomics/NextDenovo: Fast and accurate de novo assembler for long reads
github.com
August 8, 2023 at 12:15 PM
Just tried out NextDenovo (https://github.com/Nextomics/NextDenovo/) for an Arabidopsis genome assembly and I am really pleased with the outcome! The assembly looks great so far and the run time was really short. Anyone doing genome assemblies should definitely give this tool a try! 🧪🧬🖥️