Shubha Bevkal
@shubhabevkal.bsky.social
New paper out !
Want to learn more about fascinating proteasome biology and Artemisinin resistance in Malaria parasites ? Check out our preprint:
www.biorxiv.org/content/10.1...
Want to learn more about fascinating proteasome biology and Artemisinin resistance in Malaria parasites ? Check out our preprint:
www.biorxiv.org/content/10.1...
Stage-specific regulation of the Plasmodium falciparum proteasome activity reveals adaptive rewiring in artemisinin resistance
The ubiquitin-proteasome system (UPS) is essential for Plasmodium falciparum to maintain protein homeostasis, adapt to proteotoxic stress, and regulate parasite growth and stage transitions. The prote...
www.biorxiv.org
November 26, 2025 at 11:21 PM
New paper out !
Want to learn more about fascinating proteasome biology and Artemisinin resistance in Malaria parasites ? Check out our preprint:
www.biorxiv.org/content/10.1...
Want to learn more about fascinating proteasome biology and Artemisinin resistance in Malaria parasites ? Check out our preprint:
www.biorxiv.org/content/10.1...
Reposted by Shubha Bevkal
This week's issue of #ScienceTranslationalMedicine has arrived!
A transcriptional signature could inform smarter antibiotic use in newborns with sepsis, an approved medication boosts anti-malaria immunity in volunteers, and more. https://scim.ag/43PsmE6
A transcriptional signature could inform smarter antibiotic use in newborns with sepsis, an approved medication boosts anti-malaria immunity in volunteers, and more. https://scim.ag/43PsmE6
November 26, 2025 at 10:00 PM
This week's issue of #ScienceTranslationalMedicine has arrived!
A transcriptional signature could inform smarter antibiotic use in newborns with sepsis, an approved medication boosts anti-malaria immunity in volunteers, and more. https://scim.ag/43PsmE6
A transcriptional signature could inform smarter antibiotic use in newborns with sepsis, an approved medication boosts anti-malaria immunity in volunteers, and more. https://scim.ag/43PsmE6
Reposted by Shubha Bevkal
Publication alert! 🔔 Our recent work exploring how Plasmodium uses a Rad51 independent homologous recombination to diversify its var gene repertoire is now published in 🧬 Nucleic Acids Research! @oupprimary.bsky.social @narjournal.bsky.social Read more here.
tinyurl.com/794brb6h
tinyurl.com/794brb6h
Validate User
tinyurl.com
November 26, 2025 at 4:16 PM
Publication alert! 🔔 Our recent work exploring how Plasmodium uses a Rad51 independent homologous recombination to diversify its var gene repertoire is now published in 🧬 Nucleic Acids Research! @oupprimary.bsky.social @narjournal.bsky.social Read more here.
tinyurl.com/794brb6h
tinyurl.com/794brb6h
Reposted by Shubha Bevkal
Rad53 regulates RNase H1, which promotes DNA replication through sites of transcription-replication conflict
Rad53 regulates RNase H1, which promotes DNA replication through sites of transcription-replication conflict
Wagner et al. demonstrate that RNase H1 only removes a subset of R-loops in vivo. In yeast, overexpressed RNH1 acts more frequently at dysregulated R-loops and infrequently, if at all, at other RNA-DNA hybrids. Endogenous Rnh1 is induced in a Rad53-dependent manner at transcription-replication conflicts to promote replication completion.
dlvr.it
November 25, 2025 at 1:35 PM
Rad53 regulates RNase H1, which promotes DNA replication through sites of transcription-replication conflict
Reposted by Shubha Bevkal
Single-dose #malaria #treatment using four drugs achieves high cure rates in clinical trial
www.malariaworld.org/news/single-...
www.malariaworld.org/news/single-...
November 25, 2025 at 3:34 PM
Single-dose #malaria #treatment using four drugs achieves high cure rates in clinical trial
www.malariaworld.org/news/single-...
www.malariaworld.org/news/single-...
Reposted by Shubha Bevkal
Congratulations to the Weill Cornell Malaria group on completing a Marathon Relay to support the NYC Amory. Sweating for fun and a good cause is a great distraction from some of the more troubling current events in our world.
April 27, 2025 at 6:45 PM
Congratulations to the Weill Cornell Malaria group on completing a Marathon Relay to support the NYC Amory. Sweating for fun and a good cause is a great distraction from some of the more troubling current events in our world.