Sander Granneman
sgrannem.bsky.social
Sander Granneman
@sgrannem.bsky.social
Professor in RNA Biochemistry at the University of Edinburgh
www.biorxiv.org/content/10.1...
A method for rapidly and fully reversibly depleting proteins from the nucleus. Ideal for studying transcription dynamics!
A simple, reversible and non-toxic anchor-away system for effective nuclear depletion of proteins
The anchor-away (AA) technique enables rapid depletion of nuclear proteins by tethering them to cytoplasmic anchors through rapamycin-induced heterodimerisation. Albeit powerful, in Saccharomyces cere...
www.biorxiv.org
November 30, 2025 at 9:17 AM