David Serota
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serotavirus.bsky.social
David Serota
@serotavirus.bsky.social
Infectious disease (🤒🤮) + addiction medicine (🍺💉) doctor in Miami. Infections due to substance use, HIV, S. aureus, pizza, antibiotic sommelier. Research: https://scholar.google.com/citations?user=69H73JoAAAAJ&hl=en&oi=ao
Just had a paper returned by a journal after 3 days for not including the country in the affiliations, not including on the title page "number of tables: 0; number of figures: 0". What a waste of time...
September 10, 2025 at 1:18 PM
Awesome study. First RCT I know of specifically focused on hospitalized people with OUD and infectious diseases. XR-bupe no better than standard MOUD for OUD and ID outcomes.

jamanetwork.com/journals/jam...
Initiating Injectable Buprenorphine in People Hospitalized With Infections
This randomized clinical trial of patients with opioid use disorder (OUD) hospitalized for infection examines whether initiating long-acting buprenorphine plus infectious disease management vs treatme...
jamanetwork.com
June 3, 2025 at 12:15 PM
Reposted by David Serota
@steventong.bsky.social presents the results of the PSSA domain of the SNAP 🫰 trial - the worlds largest trial of staph aureus bacteremia - at #ESCMID2025

fluclox resulted in higher mortality and more AKI compared to penicillin for PSSA
April 12, 2025 at 2:45 PM
HIV treatment @ harm reduction organizations is the future! Avoids interacting with the traditional healthcare system as much as possible and bring treatment to the people. 79% viral suppression at 12 months in this pilot study. Multi-center RCT is ongoing @hivma.bsky.social doi.org/10.1080/0785...
Rapid initiation of antiretrovirals at a syringe services program for people with HIV who inject drugs
People who inject drugs (PWID) living with HIV are less likely to receive care at early disease stages and have low rates of viral suppression. This study examined the feasibility and acceptability...
doi.org
February 10, 2025 at 6:25 PM
Is there any reason to check HLA-B5701 or any reason to start someone on abacavir in 2025? We will need a new random ART factoid to quiz people on if this practice goes away.
January 6, 2025 at 2:19 PM
MRI for diagnosis of diabetic foot osteomyelitis: Pretty good positive LR (5.1), very good negative LR (0.12)
jamanetwork.com/journals/jam... #IDsky
November 27, 2024 at 2:14 PM
Rampant housing discrimination for people with OUD in S. Florida: 16% allowed residents to be on buprenorphine unconditionally, 31% allowed bupe with dose limitations, and 53% completely prohibit being on bupe.
www.sciencedirect.com/science/arti...
Limited acceptance of buprenorphine in recovery residences in South Florida: A secret shopper survey
Buprenorphine is a first-line treatment for opioid use disorder (OUD), essential for reducing opioid overdose mortality and improving treatment retent…
www.sciencedirect.com
November 21, 2024 at 3:03 PM
Make statins OTC.
April 23, 2024 at 2:31 PM
New nanoformulation technique was able to turn TDF-3TC-DTG into a monthly injectable reaching therapeutic levels within 24 hrs after injection. Very exciting #idsky journals.lww.com/aidsonline/a...
A novel formulation enabled transformation of 3-HIV drugs... : AIDS
P) technology to stabilize multiple HIV drugs, the 3-HIV drugs TLD, with disparate physical-chemical properties, are stabilized and assembled with lipid-excipients to form TLD-in-DcNP. TLD-in-DcNP is ...
journals.lww.com
October 25, 2023 at 11:37 PM
For my first bsky post, an EXCLUSIVE free idea for an ID clinical trial design: Take people reporting penicillin allergy and randomize to just ignoring it and giving whatever antibiotic you think is best vs. going through whatever the standard rigamarole is at your hospital (treatment-as-usual) 💊
October 17, 2023 at 8:45 PM