This is what I need today.

Last November, we migrated the Michigan Imputation Server (imputationserver.sph.umich.edu) to a new software stack, including Nextflow. After some turbulence, we are more and more returning to normal operations, processing around 800.000 full human genomes per month.

Today @michaelmoor.bsky.social took a train from Zurich to Innsbruck to kick-off our new Faculty of "AI and Scientific Computing"! 🎉 He talked about LLMs and Medical AI Agents. Exciting science and great discussions! Thanks! More info about our faculty: aiscm.i-med.ac.at #ai #scientificcomputing

Silvia is excited, we are so excited. Follow Silvia for great science and great fun.

www.youtube.com/watch?v=8iwB...

🚀 Ready to kick off our Nextflow in Genomics workshop tomorrow at @i-med.ac.at!
🎉 Together with @lukfor.bsky.social & @silvidm.bsky.social we'll work on improving imputation server workflows.

Big thanks to @nextflow.io, @evanfloden.bsky.social, and @ewels.bsky.social for the support.

If you didn't hear back from me today, it's because I had to solve a 4th grade math test first.

Are you working with one of the genotype imputation servers? Then this is your chance to see new features pretty soon on the server: @lukfor.bsky.social ky.social, @silvidm.bsky.social, and I are hosting our 2nd Nextflow in Genomics Hackathon to boost imputation servers here @i-med.ac.at
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Publishing software is often easier than maintaining it - but we’re committed to keeping ours up to date! 🛠️ We've enhanced the documentation for our mtDNA variant calling pipeline, with detailed guides for both graphical and command-line use with Nextflow:
mitoverse.readthedocs.io/mtdna-server...

Publishing software is often easier than maintaining it - but we’re committed to keeping ours up to date! 🛠️ We've enhanced the documentation for our mtDNA variant calling pipeline, with detailed guides for both graphical and command-line use with Nextflow:
mitoverse.readthedocs.io/mtdna-server...

endless slopes

This summer, @lukfor.bsky.social and I migrated the Michigan Imputation Server to Nextflow. 2M genomes later, we can say it was a big success.

As a Christmas gift, we’re excited to show you how to set up your own local server in under 10 minutes.

##freeimputation

genepi.github.io/michigan-imp...

Last week was fun! We had the pleasure of welcoming a MINT high school to our institute to talk about A.I 🤖. We also dived into Genetics (by @stncsn.bsky.social), Medicine, and discussed their project on AI-powered shark detection. 🧬🩺🦈 #STEM #MINT #Education #AI #Genetics @meduniibk.bsky.social

Today @silvidm.bsky.social delivered an impressive talk on her latest research on repetitive regions in the human genome - could they hold the key to the missing heritability? Huge thanks to the Biocenter @meduniibk.bsky.social for hosting this. #ukb #nextflow #lpa #vntrs

A typical shot from my life as a researcher at @meduniibk.bsky.social. Standing in the HPC center with Silvia Di Maio and looking at dark genome regions

What's the story behind? 1/n

🌍 The imputation servers running on our software stack:

🛰️ Our Main Instance: imputationserver.sph.umich.edu
🛰️ TOPMed: imputation.biodatacatalyst.nhlbi.nih.gov
🛰️ MUC: imputationserver.helmholtz-munich.de

💡 Are there other imputation servers flying around?

Check out @lukfor.bsky.social and my latest work to run Nextflow graphically. Cloudgene3 powers major genotype imputation servers (Michigan, TOPMed, Helmholtz Munich—you name it).

It’s like a referee in football—when no one is complaining, you know it’s doing an excellent job! ⚽ 🧬
shorturl.at/pdeGk