Charles University, Faculty of Science
@sciencecharles.bsky.social
#biology #chemistry #geology #geography #enviromentalsciences
Prague, Czechia
web: https://natur.cuni.cz/en
Prague, Czechia
web: https://natur.cuni.cz/en
Building complex rings with precision 🔬🧩 A new #Pd-catalyzed tandem Heck/Suzuki strategy delivers strained 5,5,6-fused tricyclic γ-lactones with three consecutive stereocenters from simple feedstocks, opening doors for #synthetic and #medicinal #chemistry.
🔗 buff.ly/pwYvQKz
(MK)
🔗 buff.ly/pwYvQKz
(MK)
January 22, 2026 at 10:48 AM
Building complex rings with precision 🔬🧩 A new #Pd-catalyzed tandem Heck/Suzuki strategy delivers strained 5,5,6-fused tricyclic γ-lactones with three consecutive stereocenters from simple feedstocks, opening doors for #synthetic and #medicinal #chemistry.
🔗 buff.ly/pwYvQKz
(MK)
🔗 buff.ly/pwYvQKz
(MK)
🌟 Prestigious EMBO Installation Grant awarded to Faculty of Science at @unikarlova.cuni.cz!
Dr. Matouš Vobořil (Dept. of Cell Biology) is building a new team studying T‑cell development and autoimmune diseases. Congratulations! 🔬👏
Dr. Matouš Vobořil (Dept. of Cell Biology) is building a new team studying T‑cell development and autoimmune diseases. Congratulations! 🔬👏
January 21, 2026 at 4:26 PM
🌟 Prestigious EMBO Installation Grant awarded to Faculty of Science at @unikarlova.cuni.cz!
Dr. Matouš Vobořil (Dept. of Cell Biology) is building a new team studying T‑cell development and autoimmune diseases. Congratulations! 🔬👏
Dr. Matouš Vobořil (Dept. of Cell Biology) is building a new team studying T‑cell development and autoimmune diseases. Congratulations! 🔬👏
President Petr Pavel yesterday appointed rectors of ten public universities at Prague Castle, including Prof. Jiří Zima, former Dean of the Faculty of Science, @unikarlova.cuni.cz 🎓🇨🇿 From February, he will lead Charles University until 2030. 🌍✨
Congratulations!
Congratulations!
January 21, 2026 at 8:57 AM
President Petr Pavel yesterday appointed rectors of ten public universities at Prague Castle, including Prof. Jiří Zima, former Dean of the Faculty of Science, @unikarlova.cuni.cz 🎓🇨🇿 From February, he will lead Charles University until 2030. 🌍✨
Congratulations!
Congratulations!
Why are the Andes richer in plant species than the African mountains? 🏞🌱 Not because the species have broader niches - but because they may partition resources more effectively. Read the new study focused on tropical alpine ecosystems:
🔗 onlinelibrary.wiley.com/doi/epdf/10....
(TŽ)
🔗 onlinelibrary.wiley.com/doi/epdf/10....
(TŽ)
January 20, 2026 at 11:37 AM
Why are the Andes richer in plant species than the African mountains? 🏞🌱 Not because the species have broader niches - but because they may partition resources more effectively. Read the new study focused on tropical alpine ecosystems:
🔗 onlinelibrary.wiley.com/doi/epdf/10....
(TŽ)
🔗 onlinelibrary.wiley.com/doi/epdf/10....
(TŽ)
The online meeting for those interested in international internships and start-up grants is here! ⏰ It will take place on Thursday, 12 February, from 10:00 AM.
📩 To receive the invitation with the link, email experientia@experientia.cz
We look forward to seeing you!
📩 To receive the invitation with the link, email experientia@experientia.cz
We look forward to seeing you!
Online meeting pro zájemce o zahraniční stáže a start-up granty je tady! ⏰ Koná se už ve čtvrtek 12. února od 10:00.
📩 O pozvánku s odkazem si napište na e-mail experientia@experientia.cz.
Těšíme se na vás!
📩 O pozvánku s odkazem si napište na e-mail experientia@experientia.cz.
Těšíme se na vás!
January 19, 2026 at 3:27 PM
The online meeting for those interested in international internships and start-up grants is here! ⏰ It will take place on Thursday, 12 February, from 10:00 AM.
📩 To receive the invitation with the link, email experientia@experientia.cz
We look forward to seeing you!
📩 To receive the invitation with the link, email experientia@experientia.cz
We look forward to seeing you!
Reposted by Charles University, Faculty of Science
#research #medchem #neurodegeneration
Investigating NFE2L1 activators for targeted protein aggregate clearance: a follow-up study
(Smahelova, Saskova) – RSC Med. Chem.: doi.org/10.1039/D5MD...
@iocbprague.bsky.social @czechacademy.bsky.social @sciencecharles.bsky.social #biocev
Investigating NFE2L1 activators for targeted protein aggregate clearance: a follow-up study
(Smahelova, Saskova) – RSC Med. Chem.: doi.org/10.1039/D5MD...
@iocbprague.bsky.social @czechacademy.bsky.social @sciencecharles.bsky.social #biocev
January 19, 2026 at 3:03 PM
#research #medchem #neurodegeneration
Investigating NFE2L1 activators for targeted protein aggregate clearance: a follow-up study
(Smahelova, Saskova) – RSC Med. Chem.: doi.org/10.1039/D5MD...
@iocbprague.bsky.social @czechacademy.bsky.social @sciencecharles.bsky.social #biocev
Investigating NFE2L1 activators for targeted protein aggregate clearance: a follow-up study
(Smahelova, Saskova) – RSC Med. Chem.: doi.org/10.1039/D5MD...
@iocbprague.bsky.social @czechacademy.bsky.social @sciencecharles.bsky.social #biocev
🎓 Faculty Schools of the Faculty of Science at @unikarlova.cuni.cz were officially appointed on 16 Jan 2026. The event highlighted long-term cooperation in science education, teacher training, and new opportunities for collaboration with partner schools. 🌿🔬
January 19, 2026 at 11:30 AM
🎓 Faculty Schools of the Faculty of Science at @unikarlova.cuni.cz were officially appointed on 16 Jan 2026. The event highlighted long-term cooperation in science education, teacher training, and new opportunities for collaboration with partner schools. 🌿🔬
Reposted by Charles University, Faculty of Science
📢 Huge congrats to David Storch & colleagues! Their paper is featured on the cover of Trends Ecol. Evol. (@cp-trendsecolevo.bsky.social), proposing a unifying theory of global biodiversity dynamics – and what it means for the future!
📖 doi.org/10.1016/j.tr...
🌍 #Biodiversity #Ecology #Evolution
📖 doi.org/10.1016/j.tr...
🌍 #Biodiversity #Ecology #Evolution
January 16, 2026 at 10:45 AM
📢 Huge congrats to David Storch & colleagues! Their paper is featured on the cover of Trends Ecol. Evol. (@cp-trendsecolevo.bsky.social), proposing a unifying theory of global biodiversity dynamics – and what it means for the future!
📖 doi.org/10.1016/j.tr...
🌍 #Biodiversity #Ecology #Evolution
📖 doi.org/10.1016/j.tr...
🌍 #Biodiversity #Ecology #Evolution
🎓🔬 Four scientists from our faculty at @unikarlova.cuni.cz, succeeded in the internal grant call Returns to CU.
Successful applicants: Kateřina Steinová, Kateřina Koštířová & Kristina Kverková (Dept. of Zoology) and Petra Cikrtová (Dept. of Parasitology). Congratulations!👏
Successful applicants: Kateřina Steinová, Kateřina Koštířová & Kristina Kverková (Dept. of Zoology) and Petra Cikrtová (Dept. of Parasitology). Congratulations!👏
January 15, 2026 at 4:13 PM
🎓🔬 Four scientists from our faculty at @unikarlova.cuni.cz, succeeded in the internal grant call Returns to CU.
Successful applicants: Kateřina Steinová, Kateřina Koštířová & Kristina Kverková (Dept. of Zoology) and Petra Cikrtová (Dept. of Parasitology). Congratulations!👏
Successful applicants: Kateřina Steinová, Kateřina Koštířová & Kristina Kverková (Dept. of Zoology) and Petra Cikrtová (Dept. of Parasitology). Congratulations!👏
🧪 Why do proteins enter charged #polymer brushes on the “wrong” side of their isoelectric point? New insights show #charge regulation drives charge inversion via pH gradients, enabling uptake, while charge patchiness needs explicit #simulations to capture the full picture.
🔗 buff.ly/SgDF8DA
(MK)
🔗 buff.ly/SgDF8DA
(MK)
January 15, 2026 at 10:48 AM
🧪 Why do proteins enter charged #polymer brushes on the “wrong” side of their isoelectric point? New insights show #charge regulation drives charge inversion via pH gradients, enabling uptake, while charge patchiness needs explicit #simulations to capture the full picture.
🔗 buff.ly/SgDF8DA
(MK)
🔗 buff.ly/SgDF8DA
(MK)
How do bacteria sense the right temperature to thrive?
A newly discovered protein, CrsL, modulates the key transcription factor CarD in mycobacteria.
By tuning CarD interaction with RNA polymerase, CrsL controls life-dependent reactions to temperature.
🔗 academic.oup.com/nar/article/...
(TŽ)
A newly discovered protein, CrsL, modulates the key transcription factor CarD in mycobacteria.
By tuning CarD interaction with RNA polymerase, CrsL controls life-dependent reactions to temperature.
🔗 academic.oup.com/nar/article/...
(TŽ)
January 13, 2026 at 11:16 AM
How do bacteria sense the right temperature to thrive?
A newly discovered protein, CrsL, modulates the key transcription factor CarD in mycobacteria.
By tuning CarD interaction with RNA polymerase, CrsL controls life-dependent reactions to temperature.
🔗 academic.oup.com/nar/article/...
(TŽ)
A newly discovered protein, CrsL, modulates the key transcription factor CarD in mycobacteria.
By tuning CarD interaction with RNA polymerase, CrsL controls life-dependent reactions to temperature.
🔗 academic.oup.com/nar/article/...
(TŽ)
Reposted by Charles University, Faculty of Science
Three days left to apply to the #EGU26 #tropicalpeatlands session! www.egu26.eu/session/56526
@nickgirkin.bsky.social
@egu.eu
@sciencecharles.bsky.social
@nickgirkin.bsky.social
@egu.eu
@sciencecharles.bsky.social
January 12, 2026 at 9:41 AM
Three days left to apply to the #EGU26 #tropicalpeatlands session! www.egu26.eu/session/56526
@nickgirkin.bsky.social
@egu.eu
@sciencecharles.bsky.social
@nickgirkin.bsky.social
@egu.eu
@sciencecharles.bsky.social
Reposted by Charles University, Faculty of Science
1/🧵 Paper out! 🎉🌿🔒
VegVault is now published in Nature Scientific Data: a global database linking palaeo + modern vegetation with traits + climate/soil drivers.
🌐website: bit.ly/VegVault
📜paper: doi.org/10.1038/s415...
#VegVault #Ecology #Paleoecology #Vegetation #FunctionalTraits
VegVault is now published in Nature Scientific Data: a global database linking palaeo + modern vegetation with traits + climate/soil drivers.
🌐website: bit.ly/VegVault
📜paper: doi.org/10.1038/s415...
#VegVault #Ecology #Paleoecology #Vegetation #FunctionalTraits
January 12, 2026 at 10:02 AM
1/🧵 Paper out! 🎉🌿🔒
VegVault is now published in Nature Scientific Data: a global database linking palaeo + modern vegetation with traits + climate/soil drivers.
🌐website: bit.ly/VegVault
📜paper: doi.org/10.1038/s415...
#VegVault #Ecology #Paleoecology #Vegetation #FunctionalTraits
VegVault is now published in Nature Scientific Data: a global database linking palaeo + modern vegetation with traits + climate/soil drivers.
🌐website: bit.ly/VegVault
📜paper: doi.org/10.1038/s415...
#VegVault #Ecology #Paleoecology #Vegetation #FunctionalTraits
Sensitive #selenium #analysis just got a boost 🔬 TiO₂-assisted #photochemical vapor generation overcomes selenate inertness, achieving >60% efficiency, strong salt tolerance, and reliable Se detection even in seawater—where particle size matters more than crystal phase.
🔗 buff.ly/k3xTaKv
(MK)
🔗 buff.ly/k3xTaKv
(MK)
January 9, 2026 at 10:02 AM
Sensitive #selenium #analysis just got a boost 🔬 TiO₂-assisted #photochemical vapor generation overcomes selenate inertness, achieving >60% efficiency, strong salt tolerance, and reliable Se detection even in seawater—where particle size matters more than crystal phase.
🔗 buff.ly/k3xTaKv
(MK)
🔗 buff.ly/k3xTaKv
(MK)
🎓🧪 Proud of your bachelor thesis? Submit it by Feb 15 for a chance to win 50,000 CZK. More info & application: experientia.cz/via-chimica
January 8, 2026 at 3:16 PM
🎓🧪 Proud of your bachelor thesis? Submit it by Feb 15 for a chance to win 50,000 CZK. More info & application: experientia.cz/via-chimica
📢 Postdoctoral position in landslide dynamics at @unikarlova.cuni.cz, Prague. Join the project Redefining Landslide Dynamics led by Sunit Das (@sdearthsci.bsky.social) , focusing on geomorphology, remote sensing & GIS. Apply by 20 Jan 2026 🌍🧑🔬
More info: 1url.cz/TJxq2
More info: 1url.cz/TJxq2
January 8, 2026 at 2:48 PM
📢 Postdoctoral position in landslide dynamics at @unikarlova.cuni.cz, Prague. Join the project Redefining Landslide Dynamics led by Sunit Das (@sdearthsci.bsky.social) , focusing on geomorphology, remote sensing & GIS. Apply by 20 Jan 2026 🌍🧑🔬
More info: 1url.cz/TJxq2
More info: 1url.cz/TJxq2
#Metastasis causes most #cancer deaths—but #migrastatics could change that. 🧬 New insights highlight #cytochalasans as promising anti-metastatic agents targeting actin-driven cell migration, with future progress hinging on systematic screening & reduced toxicity. Read more 🔽
🔗 buff.ly/O6C7gJq
(MK)
🔗 buff.ly/O6C7gJq
(MK)
January 7, 2026 at 11:01 AM
#Metastasis causes most #cancer deaths—but #migrastatics could change that. 🧬 New insights highlight #cytochalasans as promising anti-metastatic agents targeting actin-driven cell migration, with future progress hinging on systematic screening & reduced toxicity. Read more 🔽
🔗 buff.ly/O6C7gJq
(MK)
🔗 buff.ly/O6C7gJq
(MK)
🌍 Join ICYG 2026 (14–17 May, Kostelec nad Černými lesy, CZ)! Early-career geoscientists welcome. Submit abstracts by 28 Feb, register by 15 Feb. Affordable student participation, plenary by Prof. Simon Jowitt & travel grants!
Info: www.icyg.eu⚒️
Info: www.icyg.eu⚒️
January 5, 2026 at 3:22 PM
🌍 Join ICYG 2026 (14–17 May, Kostelec nad Černými lesy, CZ)! Early-career geoscientists welcome. Submit abstracts by 28 Feb, register by 15 Feb. Affordable student participation, plenary by Prof. Simon Jowitt & travel grants!
Info: www.icyg.eu⚒️
Info: www.icyg.eu⚒️
A new study in Nature Communications has challenged 50-year-old dogma by revealing that vaccinia virus mRNAs with 5'-poly(A) leaders lack the 5' m7G caps. This unexpected finding reshapes our understanding of poxvirus RNA polymerase function and viral gene expression.
More: rdcu.be/eXksT
More: rdcu.be/eXksT
Vaccinia virus mRNAs containing long 5′-poly(A)-leaders lack a canonical 5′-methylguanosine cap
Nature Communications - The vaccinia virus produces mRNA lacking the 5′ m7G cap structure. These uncapped mRNAs have long poly(A) leaders and dominate late in infection, suggesting a novel...
rdcu.be
January 5, 2026 at 8:41 AM
A new study in Nature Communications has challenged 50-year-old dogma by revealing that vaccinia virus mRNAs with 5'-poly(A) leaders lack the 5' m7G caps. This unexpected finding reshapes our understanding of poxvirus RNA polymerase function and viral gene expression.
More: rdcu.be/eXksT
More: rdcu.be/eXksT
💔 We are deeply saddened by the passing of Prof. Ivan Hirsch, emeritus professor at the Department of Genetics and Microbiology. He shared his knowledge generously, inspired many young colleagues, and left a lasting mark on science. He will always be remembered in our hearts. 🕯️
December 19, 2025 at 3:50 PM
💔 We are deeply saddened by the passing of Prof. Ivan Hirsch, emeritus professor at the Department of Genetics and Microbiology. He shared his knowledge generously, inspired many young colleagues, and left a lasting mark on science. He will always be remembered in our hearts. 🕯️
New study identifies CrsL, a key protein regulating gene expression in mycobacteria. By interacting with CarD and RNAP, CrsL helps bacteria adapt to temperature stress. Corresponding author: Jarmila Hnilicová, Dept. of Genetics and Microbiology. 🧬
Nucleid Acid Research: 1url.cz/JJYvp
Nucleid Acid Research: 1url.cz/JJYvp
Expanding the CarD interaction network: CrsL is a novel transcription regulator in actinobacteria
Abstract. Bacterial transcription regulation is critical for adaptation and survival. CarD is an essential transcription factor in mycobacteria involved in
academic.oup.com
December 19, 2025 at 3:20 PM
New study identifies CrsL, a key protein regulating gene expression in mycobacteria. By interacting with CarD and RNAP, CrsL helps bacteria adapt to temperature stress. Corresponding author: Jarmila Hnilicová, Dept. of Genetics and Microbiology. 🧬
Nucleid Acid Research: 1url.cz/JJYvp
Nucleid Acid Research: 1url.cz/JJYvp
🇨🇿🦍 Czech scientists from the Institute of Vertebrate Biology CAS and Charles University’s Faculty of Science have returned from an expedition to Dzanga-Sangha, CAR, studying entodiniomorph ciliates in lowland gorillas. The project is funded by the Czech Ministry of Education.
December 19, 2025 at 9:46 AM
🇨🇿🦍 Czech scientists from the Institute of Vertebrate Biology CAS and Charles University’s Faculty of Science have returned from an expedition to Dzanga-Sangha, CAR, studying entodiniomorph ciliates in lowland gorillas. The project is funded by the Czech Ministry of Education.
🎉 Dean honored students, staff & affiliates for presenting the Albertov Hills Revitalization at Karlov Celebrations 🌿💪 A nature-friendly project showing their engagement with the faculty surroundings. Honorees: Vojtěch Koštíř, Matouš Marek, Michal Plundra, Lucie Buchbauerová & Ondřej Sedláček.
December 18, 2025 at 10:25 AM
🎉 Dean honored students, staff & affiliates for presenting the Albertov Hills Revitalization at Karlov Celebrations 🌿💪 A nature-friendly project showing their engagement with the faculty surroundings. Honorees: Vojtěch Koštíř, Matouš Marek, Michal Plundra, Lucie Buchbauerová & Ondřej Sedláček.