@scharfmanlab.bsky.social
I am excited to share pubmed.ncbi.nlm.nih.gov/40632653/. It shows that hormones regulate hippocampal sharp-wave ripples (SPW-Rs). 1) Removing gonads decreases SPW-Rs. Hormone replacement led to recovery. 2) SPW-Rs show sex differences. And there is more! Huge thanks to all authors!
Testosterone and 17β-estradiol regulate hippocampal area CA3 sharp waves in male and female rats - PubMed
Sharp wave-ripples (SPW-Rs) are critical to hippocampal function, and the same is true of gonadal steroids, but the interactions are unclear. We find that surgical removal of the gonads greatly reduce...
pubmed.ncbi.nlm.nih.gov
August 3, 2025 at 7:09 PM
I am excited to share pubmed.ncbi.nlm.nih.gov/40632653/. It shows that hormones regulate hippocampal sharp-wave ripples (SPW-Rs). 1) Removing gonads decreases SPW-Rs. Hormone replacement led to recovery. 2) SPW-Rs show sex differences. And there is more! Huge thanks to all authors!