Sylwia Bujkiewicz
@sbujkiewicz.bsky.social
Professor of Biostatistics
Bayesian methods for evidence synthesis
Bayesian methods for evidence synthesis
Reposted by Sylwia Bujkiewicz
New paper giving a likelihood-based implementation of the Daniels & Hughes bivariate meta-analysis model for surrogate endpoint evaluations: doi.org/10.1002/bimj... We propose a bias-adjusted MLE for the variance component, present simulation results, and illustrate the method with case studies.
A New Frequentist Implementation of the Daniels and Hughes Bivariate Meta‐Analysis Model for Surrogate Endpoint Evaluation
Surrogate endpoints are used when the primary outcome is difficult to measure accurately. Determining if a measure is suitable to use as a surrogate endpoint is a challenging task and a variety of me...
doi.org
March 19, 2025 at 1:05 PM
New paper giving a likelihood-based implementation of the Daniels & Hughes bivariate meta-analysis model for surrogate endpoint evaluations: doi.org/10.1002/bimj... We propose a bias-adjusted MLE for the variance component, present simulation results, and illustrate the method with case studies.
Reposted by Sylwia Bujkiewicz
David Glynn, Pedro Saramago, Janharpreet Singh, Sylwia Bujkiewicz, Sofia Dias, Stephen Palmer, Marta Soares
Methods of multi-indication meta-analysis for health technology assessment: a simulation study
https://arxiv.org/abs/2502.13844
Methods of multi-indication meta-analysis for health technology assessment: a simulation study
https://arxiv.org/abs/2502.13844
February 20, 2025 at 5:24 AM
David Glynn, Pedro Saramago, Janharpreet Singh, Sylwia Bujkiewicz, Sofia Dias, Stephen Palmer, Marta Soares
Methods of multi-indication meta-analysis for health technology assessment: a simulation study
https://arxiv.org/abs/2502.13844
Methods of multi-indication meta-analysis for health technology assessment: a simulation study
https://arxiv.org/abs/2502.13844
📢Funded PhD on "Analytic methods for leveraging complex data to inform effective evaluation of cancer therapies", supervised by myself, @richarddriley.bsky.social , S Khan and J Singh, collaborating with AstraZeneca; D Jackson, S Khosla. For further information follow more.bham.ac.uk/mrc-aim/phd-...
PhD Opportunities – MRC AIM
more.bham.ac.uk
December 5, 2024 at 8:19 PM
📢Funded PhD on "Analytic methods for leveraging complex data to inform effective evaluation of cancer therapies", supervised by myself, @richarddriley.bsky.social , S Khan and J Singh, collaborating with AstraZeneca; D Jackson, S Khosla. For further information follow more.bham.ac.uk/mrc-aim/phd-...