Sangsoo Lee
@sangsoolee.bsky.social
Research Associate at Johns Hopkins Neurology/Neuroscience
Sleep, Circadian Rhythms, and more!
Sleep, Circadian Rhythms, and more!
Pinned
Sangsoo Lee
@sangsoolee.bsky.social
· Jul 11
linkedin.com
It’s been a rewarding journey studying sleep as a postdoc, and I’m now exploring faculty positions in neuroscience.
My latest work uncovers a neural mechanism for homeostatic sleep.
Open to opportunities and always happy to chat!
🔗 linkedin.com/in/sang-soo-lee-55b395295
My latest work uncovers a neural mechanism for homeostatic sleep.
Open to opportunities and always happy to chat!
🔗 linkedin.com/in/sang-soo-lee-55b395295
The Wu Lab at @JohnsHopkins is looking for a new postdoc fellow to study sleep and/or circadian-related behaviors in mice. If you're interested in, please contact us.
www.markwulab.net
www.markwulab.net
Wu Lab
www.markwulab.net
August 10, 2025 at 6:48 PM
The Wu Lab at @JohnsHopkins is looking for a new postdoc fellow to study sleep and/or circadian-related behaviors in mice. If you're interested in, please contact us.
www.markwulab.net
www.markwulab.net
Reposted by Sangsoo Lee
Our latest preprint is out, focusing on characterizing the response of Lhx6-positive neurons of the zona incerta (ZI) to naturally-occurring and experimentally-induced changes in the need to sleep, also known as sleep pressure.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Sleep pressure is differentially regulated by molecularly distinct subtypes of Lhx6-positive and Lhx6-negative neurons of the zona incerta
Sleep pressure, the accumulating drive towards sleep during wakefulness, is shaped by Lhx6-positive GABAergic neurons in the zona incerta (ZI). Here, we show that these neurons are broadly activated b...
www.biorxiv.org
August 5, 2025 at 2:04 PM
Our latest preprint is out, focusing on characterizing the response of Lhx6-positive neurons of the zona incerta (ZI) to naturally-occurring and experimentally-induced changes in the need to sleep, also known as sleep pressure.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A new paper from the Wu lab: "A subcircuit in the suprachiasmatic nucleus generates wakefulness", now published online in Advanced Science.
Congrats all, in particular Qiang Liu!
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Congrats all, in particular Qiang Liu!
advanced.onlinelibrary.wiley.com/doi/10.1002/...
A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness
This study identifies a sub-circuit within the circadian pacemaker suprachiasmatic nucleus (SCN) that promotes arousal. This sub-circuit is labeled by the clock output molecule mWAKE, which suppresse...
advanced.onlinelibrary.wiley.com
July 23, 2025 at 2:10 AM
A new paper from the Wu lab: "A subcircuit in the suprachiasmatic nucleus generates wakefulness", now published online in Advanced Science.
Congrats all, in particular Qiang Liu!
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Congrats all, in particular Qiang Liu!
advanced.onlinelibrary.wiley.com/doi/10.1002/...
It’s been a rewarding journey studying sleep as a postdoc, and I’m now exploring faculty positions in neuroscience.
My latest work uncovers a neural mechanism for homeostatic sleep.
Open to opportunities and always happy to chat!
🔗 linkedin.com/in/sang-soo-lee-55b395295
My latest work uncovers a neural mechanism for homeostatic sleep.
Open to opportunities and always happy to chat!
🔗 linkedin.com/in/sang-soo-lee-55b395295
linkedin.com
July 11, 2025 at 1:29 PM
It’s been a rewarding journey studying sleep as a postdoc, and I’m now exploring faculty positions in neuroscience.
My latest work uncovers a neural mechanism for homeostatic sleep.
Open to opportunities and always happy to chat!
🔗 linkedin.com/in/sang-soo-lee-55b395295
My latest work uncovers a neural mechanism for homeostatic sleep.
Open to opportunities and always happy to chat!
🔗 linkedin.com/in/sang-soo-lee-55b395295
I'm thrilled to share that my postdoctoral work is now published in @science.org. We uncovered a new circuit mechanism that regulates homeostatic sleep in mice. Huge thanks to all collaborators and supporters!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Sleep need–dependent plasticity of a thalamic circuit promotes homeostatic recovery sleep
Prolonged wakefulness leads to persistent, deep recovery sleep (RS). However, the neuronal circuits that mediate this process remain elusive. From a circuit screen in mice, we identified a group of th...
www.science.org
June 20, 2025 at 7:02 PM
I'm thrilled to share that my postdoctoral work is now published in @science.org. We uncovered a new circuit mechanism that regulates homeostatic sleep in mice. Huge thanks to all collaborators and supporters!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
I'm excited to share my first post with some great news;
our study on sleep homeostasis has been accepted! I’ll share more details once it’s published!
our study on sleep homeostasis has been accepted! I’ll share more details once it’s published!
April 30, 2025 at 4:46 PM
I'm excited to share my first post with some great news;
our study on sleep homeostasis has been accepted! I’ll share more details once it’s published!
our study on sleep homeostasis has been accepted! I’ll share more details once it’s published!
Just moved! I’ll be posting updates about my research and scientific things here!
April 30, 2025 at 4:22 PM
Just moved! I’ll be posting updates about my research and scientific things here!