We’ll build synthetic chromosomes for plants with new stress tolerance and nutrient traits. At Cai Lab, we’re rewiring DNA for more resilient, higher-value organisms.

www.manchester.ac.uk/about/news/f...

Excited to share my first contribution here at Illumina! We developed PromoterAI, a deep neural network that accurately identifies non-coding promoter variants that disrupt gene expression.🧵 (1/)

👀 On the cover. Building on our agarwood sesquiterpenoid recreation approach, this shows how photosynthetic machinery can drive P450-mediated functionalization – another step toward sustainable production of terpenes. shorturl.at/ge3lX
#GreenChemistry #synbio #algae

Today, James not only defended his PhD in genetic code expansion with precision but has been teaching me fascinating scientific insights throughout our work together. Proud to witness his academic milestone. 🧬 #SyntheticBiology #PhDSuccess

2011: Colombian kid dreams of being a surgeon
2024: PhD Bioengineering, from fighting superbugs to engineering microalgae to synthetic genomes

8 years, 3 degrees, 3 continents, 4 amazing mentors, countless experiments later.

From Colombia to Saudi Arabia to the United Kingdom.

#Latin #Scientist

🧪 Final PhD paper published! We compartmentalized sesquiterpenoid biosynthesis in algal chloroplasts, using photosynthetic electrons to drive P450-mediated oxidation without reductase partners. #algae #synbio #terpenoids

chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...