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rpeptide.bsky.social
rPeptide
@rpeptide.bsky.social
R&D Starts Here! Recombinant peptides, proteins, antibodies, reagents, and custom services for Alzheimer’s, Parkinson’s, and other neurodegenerative research.
Do you know what this could be?

#Riddle #Fun #rPeptide
February 18, 2026 at 1:15 PM
How does the brain clear toxic Tau? This Nature study found that loss of microglial REV-ERBα increases inflammation, lipid buildup, and worsens Tau pathology.

Researchers used #rPeptide’s FITC Tau-441 (T-1113) to visualize microglial Tau uptake in culture

t.ly/k0Iab

#Alzheimers #Tau #Neuroscience
Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice - Nature Communications
The circadian clock protein REV-ERBα has been implicated in neuroinflammation but mechanisms are poorly understood. Here, the authors show that microglial REV-ERBα regulates inflammatory signaling and...
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February 16, 2026 at 3:57 PM
Supporting our brain isn’t about perfection, it’s about awareness.

Small daily habits add up in powerful ways!

Let's give our minds the same care it gives us. 🧠 ✨

#BrainHealth #ScienceAndWellness #rPeptide
February 13, 2026 at 1:58 PM
Designer foldamers are helping researchers map how α-Synuclein forms toxic aggregates in Parkinson’s Disease.

By identifying the regions that drive harmful clustering, new therapeutic targets are emerging.

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#ParkinsonsResearch #ProteinAggregation #rPeptide
Foldamers reveal and validate therapeutic targets associated with toxic α-synuclein self-assembly - Nature Communications
Inhibiting alpha-synuclein self-assembly into amyloid structures, associated with Parkinson’s disease, is a potential therapeutic intervention. Here, the authors identify the domains/sequences that ar...
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February 11, 2026 at 8:16 PM
A 25-year Swedish study found that higher intake of full-fat cheese and cream was linked to a lower risk of dementia in adults without genetic Alzheimer’s risk, though balanced diet and lifestyle likely play a big role too 🧀

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#BrainHealth #DementiaResearch #NutritionScience #Neuroscience
A 25-year study found an unexpected link between cheese and dementia
A massive Swedish study tracking nearly 28,000 people for 25 years found an unexpected link between full-fat dairy and brain health. Among adults without a genetic risk for Alzheimer’s, eating more fu...
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February 9, 2026 at 6:51 PM
Curiosity is what keeps the fire alive ✨

#MindfulScience #Curiosity #BrainWellness #rPeptide
February 6, 2026 at 2:01 PM
A new study highlights how astaxanthin may help protect the brain by supporting Beta-Amyloid clearance and reducing inflammation associated with Alzheimer’s Disease.

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#Neuroscience #AlzheimersDisease #Inflammation #rPeptide
Astaxanthin enhances autophagy, amyloid beta clearance and exerts anti-inflammatory effects in in vitro models of Alzheimer’s disease-related blood brain barrier dysfunction and inflammation
Defective degradation and clearance of amyloid-β as well as inflammation per se are crucial players in the pathology of Alzheimer’s disease (AD). A de…
t.ly
February 4, 2026 at 6:10 PM
Giving your brain a moment to reset can support clarity, calm, and sustained focus throughout the day. ✨

#BrainHealth #NervousSystemReset #Wellbeing
February 2, 2026 at 5:31 PM
New research suggests Alzheimer’s may trick the brain into erasing memories by activating a receptor that tells neurons to prune synapses, linking amyloid and inflammation in the same pathway.

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#AlzheimersResearch #Neuroscience #BrainHealth #Neurodegeneration
Alzheimer’s may trick the brain into erasing its own memories
Alzheimer’s may destroy memory by flipping a single molecular switch that tells neurons to prune their own connections. Researchers found that both amyloid beta and inflammation converge on the same r...
t.ly
January 30, 2026 at 7:07 PM
New research shows antisense oligonucleotides can reliably lower Tau, including pathological forms, in mouse models of Alzheimer’s and tauopathies.

rPeptide’s Tau-441 (T-1001) was used as a standard to track Tau reduction.

t.ly/wTqY_

#Neuroscience #Tau #Alzheimers #rPeptide
Frontiers | Evaluating the efficacy of purchased antisense oligonucleotides to reduce mouse and human tau in vivo
Many preclinical and clinical studies support the use of antisense oligonucleotides (ASOs) as effective therapeutic strategies. However, acquiring ASOs for r...
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January 28, 2026 at 1:59 PM
Reposted by rPeptide
Explore @rpeptide.bsky.social expert products for #Alzheimers and #Parkinsons disease research

including antibodies recombinant #proteins, #peptides, preformed #fibrils for #BetaAmyloid, #Tau, #Synuclein, #Calmodulin...

Learn More here: www.stratech.co.uk/our-partners...

#neuroscience #neurology
January 23, 2026 at 3:02 PM
Our January Raffle Riddle winner is Nicole! 🎉

Please check your email to claim your prize.

Thank you to everyone who participated!

#WinnerAnnouncement #rPeptide #Raffle #Prize
January 23, 2026 at 3:52 PM
January 21, 2026 at 7:46 PM
Early loss of smell may be more than a symptom, it may reflect early #Parkinsons pathology.

A new study shows #AlphaSynuclein aggregation drives both neuron loss and olfactory deficits in PD models. rPeptide’s Alpha-Synuclein and ready-to-use PFFs supported this work.

t.ly/ouvq9

#rPeptide
Dopaminergic neurodegeneration in the substantia nigra is associated with olfactory dysfunction in mice models of Parkinson’s disease - Cell Death Discovery
Cell Death Discovery - Dopaminergic neurodegeneration in the substantia nigra is associated with olfactory dysfunction in mice models of Parkinson’s disease
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January 19, 2026 at 6:42 PM
When your lab equipment takes learning seriously!

#ScienceFun #LabJokes #ResearchHumor #RDStartsHere #rPeptide
January 16, 2026 at 1:54 PM
This month’s riddle lives in every experiment…take a guess!

#RaffleRiddle #ScienceFun #rPeptide
January 14, 2026 at 1:47 PM
New research maps how #BetaAmyloid 1-40 aggregates over time, showing how factors like temperature shape fibril formation in Alzheimer’s disease.

#rPeptide Beta-Amyloid 1-40 (A-1001) was used to track aggregation kinetics and morphology.

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#Neuroscience #Alzheimers #ProteinAggregation
The kinetics of aggregation of the Aβ1-40 peptide monitored by magnetooptical methods
Protein misfolding leads to the formation of amyloid fibrils, which presence is characterized for many serious diseases affecting millions of people w…
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January 12, 2026 at 4:57 PM
Tiny cellular systems, big impact on brain health!

#BrainFacts #Neuroscience #TakingCareOfYourMind #rPeptide
January 9, 2026 at 1:50 PM
New research shows eMI and CMA work together to clear aggregation-prone proteins under stress, pathways disrupted in AD and PD.

Our Tau-441 (T-1001) and α-Synuclein (S-1001) were used to track how cells manage these proteins.

t.ly/7Tgdo

#Neuroscience #Autophagy #Neurodegeneration #rPeptide
Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy
Krause et al. show compensatory mechanisms between chaperone-mediated autophagy and endosomal microautophagy (eMI) facilitated by Bag6, which is required for substrate internalization by eMI. Changes ...
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January 7, 2026 at 5:17 PM
New research shows Alzheimer’s damage can be reversed in mice by restoring brain energy balance, even after symptoms appear. 🧠⚡️

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#Alzheimers #Neuroscience #BrainHealth #Research #rPeptide
Scientists reverse Alzheimer’s in mice and restore memory
Alzheimer’s has long been considered irreversible, but new research challenges that assumption. Scientists discovered that severe drops in the brain’s energy supply help drive the disease—and restorin...
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January 5, 2026 at 3:43 PM
Just like good research, brain health is built step by step 🧠 ✨

#Neuroscience #BrainHealth #NewYear #rPeptide
January 2, 2026 at 1:26 PM
Did you know numbers influence how your brain perceives space? 🧠🔢

A new study reveals that numerical understanding and spatial vision are tightly linked! Offering fresh insight into how we think and navigate the world.

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#Numbers #Perception #Neuroscience #rPeptide
Numbers in Vision Can Shift How We Perceive Space - Neuroscience News
New research reveals that numbers in our visual field can subtly distort how we judge spatial positions, showing that perception is shaped by both numerical magnitude and object-based processing.
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December 31, 2025 at 3:47 PM
New research shows #APP helps aging immune cells protect their mitochondria and fight tumors, linking Alzheimer’s biology to aging, metabolism, and cancer. Amyloid pathways may reach far beyond the brain. 🧠⚡️

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#Neuroscience #Alzheimers #Aging #Amyloid #BrainFacts
Alzheimer’s Disease-Associated Amyloid Beta Precursor Protein Prevents Aging Stress-Induced Mitophagy and Fumarate Depletion to Improve Anti-Tumor Immunity
Alzheimer’s disease (AD) patients have a decreased incidence of cancer., with a cross-sectional analysis of a nationwide sample of adults finding 21-fold higher odds of cancer diagnosis in non-AD compared to AD patients. Here, we demonstrated that ...
t.ly
December 29, 2025 at 1:40 PM
December 24, 2025 at 3:22 PM
Researchers found monomeric Alpha-Synuclein is flexible but mechanically weak—key traits linked to aggregation in neurodegenerative disease. rPeptide’s Alpha-Synuclein (cat# S-1001) supported this work.

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#Neuroscience #ParkinsonsResearch #AlzheimersResearch #RDStartsHere #rPeptide
Physical and Mechanical Properties of Monomeric Alpha-Synuclein Provide Leads to Molecular Function
The activity of the intrinsically disordered protein, α-synuclein, in human brain neurons is associated with neurotransmitter storage, trafficking, and release, and its dysfunctional aggregation is li...
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December 22, 2025 at 4:41 PM