Ron Geller
@rongellerlab.bsky.social
Group Leader of the Viral Biology group at I2SysBio. RNA viruses, experimental evolution, amateur farming, and rock climbing. Opinions are mine, not those of the lab. 🇮🇱🇺🇸🇪🇸
You know something exciting is happening when three lab members are working together to get it done!
October 29, 2025 at 2:41 PM
You know something exciting is happening when three lab members are working together to get it done!
Reposted by Ron Geller
🚨JOB ALERT
Dr. Buceta at @i2sysbio.es welcome applications for 36-month postdocs on:
👉 Mechanical markers of tissue dysfunction due to ageing – digital twins & machine learning
Details here: fgcsic.es/convocatoria...
📩 Contact javier.buceta@csic.es to shape your proposal!
@epimechfc.bsky.social
Dr. Buceta at @i2sysbio.es welcome applications for 36-month postdocs on:
👉 Mechanical markers of tissue dysfunction due to ageing – digital twins & machine learning
Details here: fgcsic.es/convocatoria...
📩 Contact javier.buceta@csic.es to shape your proposal!
@epimechfc.bsky.social
ComFuturo Fourth Edition: ComFuturo iAGE Call - FGCSIC
The Fundación General CSIC (FGCSIC) launches the fourth edition of its ComFuturo programme: ComFuturo iAGE, a postdoctoral initiative co-financed by the Marie Skłodowska-Curie Actions COFUND scheme of...
fgcsic.es
October 13, 2025 at 1:04 PM
🚨JOB ALERT
Dr. Buceta at @i2sysbio.es welcome applications for 36-month postdocs on:
👉 Mechanical markers of tissue dysfunction due to ageing – digital twins & machine learning
Details here: fgcsic.es/convocatoria...
📩 Contact javier.buceta@csic.es to shape your proposal!
@epimechfc.bsky.social
Dr. Buceta at @i2sysbio.es welcome applications for 36-month postdocs on:
👉 Mechanical markers of tissue dysfunction due to ageing – digital twins & machine learning
Details here: fgcsic.es/convocatoria...
📩 Contact javier.buceta@csic.es to shape your proposal!
@epimechfc.bsky.social
New study! We compared the first two full-proteome Enterovirus DMS datasets and found both shared and unique selection pressures—plus conserved druggable pockets. Great collaboration with @ptdolan.bsky.social ’s team!
dx.doi.org/10.21203/rs....
@bealro.bsky.social @i2sysbio.es
dx.doi.org/10.21203/rs....
@bealro.bsky.social @i2sysbio.es
Comparative Analysis of Deep Mutational Scanning Datasets in Enteroviruses A and B Identifies Functional Divergence and Therapeutic Targets
Deep mutational scanning (DMS) can define functional constraints acting on viral proteomes by quantifying the effects of mutations on viral fitness. However, DMS analyses do not discern type-specific ...
dx.doi.org
September 8, 2025 at 9:30 AM
New study! We compared the first two full-proteome Enterovirus DMS datasets and found both shared and unique selection pressures—plus conserved druggable pockets. Great collaboration with @ptdolan.bsky.social ’s team!
dx.doi.org/10.21203/rs....
@bealro.bsky.social @i2sysbio.es
dx.doi.org/10.21203/rs....
@bealro.bsky.social @i2sysbio.es
Quedan 2 semanas para postular a un doctorado en nuestro laboratorio (interacciones arbovirus-hospedador).
🎓 Título universitario (fuera de la UE, >2020) + máster relevante requeridos.
🔍 Detalles: i2sysbio.es/position/7/.
#PhDposition #Virología #Arbovirus 🦟🧬🌍
🎓 Título universitario (fuera de la UE, >2020) + máster relevante requeridos.
🔍 Detalles: i2sysbio.es/position/7/.
#PhDposition #Virología #Arbovirus 🦟🧬🌍
i2sysbio - Position
i2sysbio.es
May 17, 2025 at 5:56 AM
Quedan 2 semanas para postular a un doctorado en nuestro laboratorio (interacciones arbovirus-hospedador).
🎓 Título universitario (fuera de la UE, >2020) + máster relevante requeridos.
🔍 Detalles: i2sysbio.es/position/7/.
#PhDposition #Virología #Arbovirus 🦟🧬🌍
🎓 Título universitario (fuera de la UE, >2020) + máster relevante requeridos.
🔍 Detalles: i2sysbio.es/position/7/.
#PhDposition #Virología #Arbovirus 🦟🧬🌍
Reposted by Ron Geller
📢 Exciting news! We will soon open two PhD positions at @i2sysbio.bsky.social @csic.es, in research projects in collaboration with the @bsc-cns.bsky.social. Both are related to tools to simulate biological tissues. Here’s the description of the open positions. #PhDpositions #PhDOpportunities
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May 6, 2025 at 8:46 AM
📢 Exciting news! We will soon open two PhD positions at @i2sysbio.bsky.social @csic.es, in research projects in collaboration with the @bsc-cns.bsky.social. Both are related to tools to simulate biological tissues. Here’s the description of the open positions. #PhDpositions #PhDOpportunities
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A recent effort from the enterovirologists in the @rongellerlab.bsky.social. Interested in making or utilizing fluorescent reporter enteroviruses? Take a look. A Fluorescent Reporter Virus Toolkit for Interrogating Enterovirus Biology and Host Interactions www.preprints.org/manuscript/2...
www.preprints.org
May 6, 2025 at 4:03 AM
A recent effort from the enterovirologists in the @rongellerlab.bsky.social. Interested in making or utilizing fluorescent reporter enteroviruses? Take a look. A Fluorescent Reporter Virus Toolkit for Interrogating Enterovirus Biology and Host Interactions www.preprints.org/manuscript/2...
4-year PhD fellowship in Virology available in our group @i2sysbio.bsky.social. Eligibility requires having a relevant university degree from outside of the EU obtained after 1/1/2020 and having (or soon to have) a relevant Master degree (preferably from Spain). See i2sysbio.es/position/7/
i2sysbio.es
April 24, 2025 at 12:07 PM
4-year PhD fellowship in Virology available in our group @i2sysbio.bsky.social. Eligibility requires having a relevant university degree from outside of the EU obtained after 1/1/2020 and having (or soon to have) a relevant Master degree (preferably from Spain). See i2sysbio.es/position/7/
Our recent collaborative work showing the promising broad-spectrum antiviral activity of chitosan sulfate derivatives against SARS-CoV-2, RSV, and Sindbis virus is finally online. Check it out! Detailed mechanisms and in vivo characterization included! rdcu.be/eb9IQ
Synthetic heparan sulfate mimics based on chitosan derivatives show broad-spectrum antiviral activity
Communications Biology - Identification of safe and effective broad-spectrum antivirals based on modified chitosan sulfate derivatives.
rdcu.be
March 4, 2025 at 12:03 PM
Our recent collaborative work showing the promising broad-spectrum antiviral activity of chitosan sulfate derivatives against SARS-CoV-2, RSV, and Sindbis virus is finally online. Check it out! Detailed mechanisms and in vivo characterization included! rdcu.be/eb9IQ
Reposted by Ron Geller
Latest #virology research from the lab! 👇
Using genetic approaches and live-cell imaging, we show that the viral 2A protease plays a critical role in subverting antiviral responses and establishing a favorable host environment to expedite enterovirus replication.
www.biorxiv.org/content/10.1...
Using genetic approaches and live-cell imaging, we show that the viral 2A protease plays a critical role in subverting antiviral responses and establishing a favorable host environment to expedite enterovirus replication.
www.biorxiv.org/content/10.1...
The critical role of enterovirus 2A protease in viral translation, replication, and antagonism of host antiviral responses
Enteroviruses dramatically remodel the cellular infrastructure for efficient replication and curtailing host antiviral responses. Proteases 2Apro and 3Cpro have been implicated in these processes base...
www.biorxiv.org
February 23, 2025 at 12:56 PM
Latest #virology research from the lab! 👇
Using genetic approaches and live-cell imaging, we show that the viral 2A protease plays a critical role in subverting antiviral responses and establishing a favorable host environment to expedite enterovirus replication.
www.biorxiv.org/content/10.1...
Using genetic approaches and live-cell imaging, we show that the viral 2A protease plays a critical role in subverting antiviral responses and establishing a favorable host environment to expedite enterovirus replication.
www.biorxiv.org/content/10.1...
Yesterday we had the first #ValenciaVirologyMeeting. Great to see we have a solid virology community right here! Thanks Rafa Sanjuan and @SantiagoFElena for helping to chair our discussion on de novo virus design and synthetic viruses and Jesus Rodriguez Diaz for co-organizing.
February 6, 2025 at 11:08 AM
Yesterday we had the first #ValenciaVirologyMeeting. Great to see we have a solid virology community right here! Thanks Rafa Sanjuan and @SantiagoFElena for helping to chair our discussion on de novo virus design and synthetic viruses and Jesus Rodriguez Diaz for co-organizing.
Making recombinant VSV? Our codon-optimized helper plasmids are now available at @Addgene: www.addgene.org/Ron_Geller/. Method details here: www.nature.com/articles/s41...
Addgene: Ron Geller Lab Materials
www.addgene.org
January 31, 2025 at 8:22 AM
Making recombinant VSV? Our codon-optimized helper plasmids are now available at @Addgene: www.addgene.org/Ron_Geller/. Method details here: www.nature.com/articles/s41...
Just shipped our optimized helper plasmids for producing recombinant VSV to Addgene/@addgene.bsky.social from our recent paper (www.nature.com/articles/s41...). Keep an eye out for them if you make recombinant VSV.
An efficient plasmid-based system for the recovery of recombinant vesicular stomatitis virus encoding foreign glycoproteins - Scientific Reports
Scientific Reports - An efficient plasmid-based system for the recovery of recombinant vesicular stomatitis virus encoding foreign glycoproteins
www.nature.com
December 20, 2024 at 10:03 AM
Just shipped our optimized helper plasmids for producing recombinant VSV to Addgene/@addgene.bsky.social from our recent paper (www.nature.com/articles/s41...). Keep an eye out for them if you make recombinant VSV.
A farewell lunch to Marianoel Pereira from Pasteur Institute of Montevideo in Uruguay who spent a couple of months in our lab learning high-fidelity Illumina sequencing of viruses.
November 30, 2024 at 6:18 PM
A farewell lunch to Marianoel Pereira from Pasteur Institute of Montevideo in Uruguay who spent a couple of months in our lab learning high-fidelity Illumina sequencing of viruses.