Ryan O'Keefe
rokeefemd.bsky.social
Ryan O'Keefe
@rokeefemd.bsky.social
MD/MBA PennMedicine/Wharton | Hospitalist | Onc, Pall Care, MedEd | Creator Point of Care Medicine | Clinical threads and pearls
⚕️September IM and Hospitalist Recap!⚕️

Hepatitis C: Are We There Yet? (UCSF Grand Rounds)

Such a fascinating history - we've come a long way, and yet there is so much to be done!

My favorite lessons below.

www.youtube.com/watch?v=XrJ...
Hepatitis C: Are We There Yet? Updates and the Road Ahead
Although curative therapies have transformed hepatitis C care, gaps in diagnosis, access, and prevention still stand in the way of its elimination. In this G...
www.youtube.com
October 30, 2025 at 8:58 PM
⚕️September IM and Hospitalist Recap!⚕️

All things HFpEF!

An oldie but a goodie! Glad this one got revisited!

Check out the linked @thecurbsiders post, and then some of my top takeaways below.

x.com/thecurbside...
October 29, 2025 at 9:00 PM
Questions from the Wards!

Check out the most recent Substack post published this AM!

After each month working in the hospital, I try to do a deep dive into a few topics / questions that came up. Here are a few of my recent favorites!

Zero fluff, high-yield. Subscribe for more to come.

Link below
October 29, 2025 at 4:00 PM
⚕️September IM and Hospitalist Recap!⚕️

One Detail Completely Changed This Case (An Unexpected Outcome) - Conan Liu MD

My takeaways, and additional thoughts on approaching hypoalbuminemia below!

www.youtube.com/watch?v=KB_...
One Detail Completely Changed This Case (An Unexpected Outcome)
Sometimes you will run across a case where one small detail completely changes the diagnostic momentum, and results in an entirely different outcome. Here is...
www.youtube.com
October 28, 2025 at 8:58 PM
⚕️September IM and Hospitalist Recap!⚕️

DOAC Failure (Curbsiders)

I've seen this a few times recently, and could have really used these insights!

Check out the linked @thecurbsiders post, and then some of my top takeaways below.

x.com/thecurbside...
October 27, 2025 at 8:58 PM
⚕️September IM and Hospitalist Recap!⚕️

Orthostatic Hypotension (Core IM)

Despite taking care of at least 1-2 patients with orthostasis each week, I still learned so much!

Check out the linked CORE IM thread, and then some of my top takeaways below.

x.com/COREIMpodca...
October 22, 2025 at 9:00 PM
IM and Hospital Medicine Recap - Best of Podcasts and YouTube from September 2025!

Check out the most recent Substack post!

My favorite lessons from podcasts across various clinic topics including orthostatic hypotension, HFpEF, DOAC failure, and more!

Zero fluff, high-yield.

Link below!
October 22, 2025 at 4:04 PM
⚕️September IM and Hospitalist Recap!⚕️

Tumor Lysis Syndrome (Review, NEJM)

Fun to read this update to their 2011 review! Always good to remind ourselves why some patients are getting q8 labs, and when to pull the trigger on rasburicase!

- Thread 🧵 -
October 21, 2025 at 8:57 PM
Some practical tips for taking care of patients with CKD in the hospital!

#TipsForHospitalists #MedEd #POCM
October 20, 2025 at 9:01 PM
IM and Hospital Medicine Recap - Best of Podcasts and YouTube from September 2025!

Check out the most recent Substack post!

My favorite lessons from podcasts across various clinic topics including orthostatic hypotension, HFpEF, DOAC failure, and more!

Zero fluff, high-yield.

Link below!
October 18, 2025 at 4:00 PM
⚕️September IM and Hospitalist Recap!⚕️

Chronic Kidney Disease (Annals of IM)

A majority of patients with CKD will die from cardiovascular disease rather than progressing to ESKD.

Here are some of my takeaways, from staging, to the 4 pillars, anemia, and inpatient pitfalls.

🧵

#MedEd #IMRecaps
October 16, 2025 at 8:59 PM
⚕️September IM and Hospitalist Recap!⚕️

Hypertrophic Cardiomyopathy Review (NEJM)

Just took care of a patient with HCM on the wards, and this came in handy!

Here are some of my favorite lessons and pearls for clinical practice!

- Thread 🧵 -

#MedEd #IMRecaps
October 15, 2025 at 9:01 PM
⚕️September IM and Hospitalist Recap!⚕️

Hypothyroidism: A Review (JAMA)

This one is absolutely LOADED with pearls!

Read on for some of my favorite lessons for clinical practice!

- Thread 🧵 -

#MedEd #IMRecaps
October 14, 2025 at 8:58 PM
⚕️September IM and Hospitalist Recap!⚕️

Large Vessel Vasculitis Review (The Lancet)

GCA is not just a disease of the temporal arteries and there's more to know than just jaw claudication and vision loss!

Read on for some of my favorite lessons for clinical practice!

- Thread 🧵 -

#MedEd #IMRecaps
October 13, 2025 at 9:01 PM
⚕️September IM and Hospitalist Recap!⚕️

Lymphadenopathy Evaluation and DDx @aafp

Not sure whether to watch and wait or go straight to biopsy?

Read on for some of my favorite lessons and pearls for clinical practice!

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#IMRecaps #MedEd
October 12, 2025 at 8:56 PM
⚕️September IM and Hospitalist Recap!⚕️

🧫Management of Staph Aureus Bacteremia Review (JAMA)

Staph aureus bacteremia has mortality worldwide of almost 30%!

Here are some of the most important things to know when co-managing these patients with your ID colleagues!

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#IMRecaps #MedEd
October 10, 2025 at 8:59 PM
⚕️September IM and Hospitalist Recap!⚕️

🦠Shigellosis Review - The Lancet

Saw this on the wards a few weeks ago and this @TheLancet review really came in handy!

Read on for some of my favorite lessons for clinical practice!

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#IMRecaps #MedEd #InfectiousDisease
October 9, 2025 at 8:58 PM
September IM and Hospitalist Recap!

Vitamin B12 Deficiency: Common Questions and Answers (AAFP)

I enjoyed this read! I see a lot of B12 deficiency in the heme/onc populations, so it felt very relevant!

Here are the most important lessons, along with some interesting factoids!

- Thread -
October 7, 2025 at 12:02 PM