Target prioritization is to bio foundation models as next token prediction is to language models

Let’s train a simple Generative Pre-trained Transformer (GPT) model and analyze its training thermodynamics using tools from statistical physics 🧵

🎉 Congratulations to Newton Cho, the 2025 winner of the Science & PINS Prize for Neuromodulation for his work identifying a novel therapeutic target to improve walking after spinal cord injury.

Learn more: scim.ag/44WlGF0

Let’s dive into Sarepta’s recent feud with FDA by building a RAG application on publicly accessible FDA documents, SEC filings, Press Reports, Publications, and Abstracts 🧵

Let’s build a data-driven, biologically relevant Liver Injury risk score using Open Targets, Pathway Commons, and FDA DILI rank dataset (100% open source) 🧵