rkothari.bsky.social
@rkothari.bsky.social
Reposted
Meningeal mast cells, via the receptor Mrgprb2/X2, orchestrate brain inflammation after stroke by recruiting and promoting the transfer of skull bone marrow neutrophils into the brain @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
July 25, 2025 at 2:11 AM
Reposted
Very excited to share our new work out today @cellpress.bsky.social. Here, we propose that meningeal mast cells regulate brain inflammation after stroke by coordinating immune infiltration from the skull bone marrow, through the meninges, and into the brain!

www.cell.com/cell/fulltex...
A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis
Meningeal mast cells, via the receptor Mrgprb2/X2, orchestrate brain inflammation after stroke by recruiting and promoting the transfer of skull bone marrow neutrophils into the brain, highlighting th...
www.cell.com
July 24, 2025 at 5:21 PM
Reposted
MrgprB2 back in the news. Stroke! Big new @cellpress.bsky.social paper with a lot of good friends on it: www.sciencedirect.com/science/arti... congrats to Ruchita, Risheng, Dr. Dong and the great @nathachitlim.bsky.social
A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis
The immune environment surrounding the brain plays a fundamental role in monitoring signs of injury. Insults, including ischemic stroke, can disrupt t…
www.sciencedirect.com
July 24, 2025 at 3:24 PM