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Paper of the day · 09.01.26
Discovery of PPARγ Partial Agonists for Treatment of Type 2 Diabetes Based on an Integrated Virtual Screening Strategy that Combines Fragment Molecular Orbital Calculations, Machine Learning, Molecular Docking, Inte...
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Discovery of PPARγ Partial Agonists for Treatment of Type 2 Diabetes Based on an Integrated Virtual Screening Strateg...

Peroxisome proliferator-activated receptor γ (PPARγ) is a key therapeutic target for type 2 diabetes and cardiovascular diseases due to its central role in regulating glucose and lipid metabolism....

doi.org

January 9, 2026 at 3:16 PM

Recep Adiyaman

@recep44.bsky.social

Job of the day · 08.01.26
European Bioinformatics Institute | EMBL-EBI hiring Research Management Office Lead in England, United Kingdom - LinkedIn (Bioinformatics Careers)
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

European Bioinformatics Institute | EMBL-EBI hiring Research Management Office Lead in England, United Kingdom - Link...

news.google.com

January 8, 2026 at 1:36 AM

Recep Adiyaman

@recep44.bsky.social

Industry news of the day · 08.01.26
Rice-led biotech symposium highlights collaboration at Texas Medical Center research hub - Rice University
Rice-led biotech symposium highlights collaboration at Texas Medical C...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Rice-led biotech symposium highlights collaboration at Texas Medical Center research hub - Rice University

Rice-led biotech symposium highlights collaboration at Texas Medical Center research hub    Rice University

news.google.com

January 8, 2026 at 1:36 AM

Recep Adiyaman

@recep44.bsky.social

AI news of the day · 08.01.26
Metabolic Reprogramming and Transcriptomic Adaptation Contribute to Glyphosate Resistance in Potato Cultivars - Frontiers
Metabolic Reprogramming and Transcriptomic Adaptation Contrib...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Metabolic Reprogramming and Transcriptomic Adaptation Contribute to Glyphosate Resistance in Potato Cultivars - Front...

Metabolic Reprogramming and Transcriptomic Adaptation Contribute to Glyphosate Resistance in Potato Cultivars    Frontiers

news.google.com

January 8, 2026 at 1:36 AM

Recep Adiyaman

@recep44.bsky.social

Paper of the day · 08.01.26
Discovery of PPARγ Partial Agonists for Treatment of Type 2 Diabetes Based on an Integrated Virtual Screening Strategy that Combines Fragment Mo...
https://doi.org/10.1021/acs.jpcb.5c06470
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

A screening strategy for bioactive components from Amaranth: An integrated approach of network pharmacology, molecula...

Amaranth is a traditional medicinal and forage plant with promising anti-inflammatory properties. To enhance its utilization in livestock and feed industries, this study investigated the bioactive...

doi.org

January 8, 2026 at 1:36 AM

Recep Adiyaman

@recep44.bsky.social

Job of the day · 07.01.26
Mercor hiring Bioinformatics Data-Science Specialist in Greater Montreal Metropolitan Area - LinkedIn (Bioinformatics Careers)
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Mercor hiring Bioinformatics Data-Science Specialist in Greater Montreal Metropolitan Area - LinkedIn (Bioinformatics...

news.google.com

January 7, 2026 at 4:55 AM

Recep Adiyaman

@recep44.bsky.social

Industry news of the day · 07.01.26
Evidence Supports Safe, Effective Switching to Etanercept Biosimilars - Center for Biosimilars
Evidence Supports Safe, Effective Switching to Etanercept Biosimilars ...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Evidence Supports Safe, Effective Switching to Etanercept Biosimilars - Center for Biosimilars

Evidence Supports Safe, Effective Switching to Etanercept Biosimilars    Center for Biosimilars

news.google.com

January 7, 2026 at 4:55 AM

Recep Adiyaman

@recep44.bsky.social

AI news of the day · 07.01.26
Monte Rosa Therapeutics to Present Interim MRT-8102 Phase 1 Study Results - The Manila Times
Monte Rosa Therapeutics to Present Interim MRT-8102 Phase 1 Study Results The...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Monte Rosa Therapeutics to Present Interim MRT-8102 Phase 1 Study Results - The Manila Times

Monte Rosa Therapeutics to Present Interim MRT-8102 Phase 1 Study Results    The Manila Times

news.google.com

January 7, 2026 at 4:55 AM

Recep Adiyaman

@recep44.bsky.social

Paper of the day · 07.01.26
SMARTDock: A Toolkit for the Automated Development of Target-Specific Scoring Functions Using Bioactivity Data.
Molecular docking has become an...
https://doi.org/10.1021/acs.jcim.5c01490
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

SMARTDock: A Toolkit for the Automated Development of Target-Specific Scoring Functions Using Bioactivity Data.

Molecular docking has become an essential tool in the early stages of structure-based drug discovery, enabling rapid virtual screening of large compound libraries against biological targets. Howeve...

doi.org

January 7, 2026 at 4:55 AM

Recep Adiyaman

@recep44.bsky.social

Job of the day · 05.01.26
Job Application for Research Associate I (Protein Scienc...
https://news.google.com/rss/articles/CBMickFVX3lxTE5CUHRjdV9TRHF4MzFMZ3dLczNsNVV4SDk3ZldJWDNlTmkxdmtKY0hqeUd4a1hjcHJZajc4SEQtTWVSaUR6REpSaVB1VzU3eGxyQWlNOVVteUo0TF8xeHpnajR1eTRHNmY4aEdfWEZ5bzR1QQ?oc=5
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Job Application for Research Associate I (Protein Science & Analytics) at EVERY™ - job-boards.greenhouse.io (Greenhouse)

news.google.com

January 5, 2026 at 8:36 PM

Recep Adiyaman

@recep44.bsky.social

Paper of the day · 05.01.26
AlphaFold for Docking Screens.
AlphaFold is an AI system developed by Google DeepMind to generate three-dimensional structures of proteins w...
https://doi.org/10.1007/978-1-0716-4949-7_13
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Assessing the validity of leucine zipper constructs predicted by AlphaFold.

AP-1 transcription factors are a network of cellular regulators that combine in different dimer pairs to control a range of pathways involved in differentiation, growth, and cell death. They dimeri...

doi.org

January 5, 2026 at 8:36 PM

Recep Adiyaman

@recep44.bsky.social

Industry news of the day · 04.01.26
Protein Engineering for Pharmaceutical Biotechnology Training Course: Understand How to Advance Ther - PharmiWeb.com
Protein Engineering for Pharmaceutical Biotechnology Trainin...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Protein Engineering for Pharmaceutical Biotechnology Training Course: Understand How to Advance Ther - PharmiWeb.com

Protein Engineering for Pharmaceutical Biotechnology Training Course: Understand How to Advance Ther    PharmiWeb.com

news.google.com

January 4, 2026 at 2:24 AM

Recep Adiyaman

@recep44.bsky.social

AI news of the day · 04.01.26
Bets on Generative AI to Redefine Drug Discovery——IntelliGenAI and Their Foundation Model Approach - Pandaily
Bets on Generative AI to Redefine Drug Discovery——IntelliGenAI and Their...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Bets on Generative AI to Redefine Drug Discovery——IntelliGenAI and Their Foundation Model Approach - Pandaily

Bets on Generative AI to Redefine Drug Discovery——IntelliGenAI and Their Foundation Model Approach    Pandaily

news.google.com

January 4, 2026 at 2:24 AM

Recep Adiyaman

@recep44.bsky.social

Paper of the day · 04.01.26
AlphaFold for Docking Screens.
AlphaFold is an AI system developed by Google DeepMind to generate three-dimensional structures of proteins w...
https://doi.org/10.1007/978-1-0716-4949-7_13
Subnewsletter
#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

AlphaFold for Docking Screens.

AlphaFold is an AI system developed by Google DeepMind to generate three-dimensional structures of proteins without experimental data. The models created with AlphaFold are available on the AlphaFo...

doi.org

January 4, 2026 at 2:24 AM

Recep Adiyaman

@recep44.bsky.social

🕯️ Protein Design Digest 🧬
A daily curated briefing for protein engineering, computational biology, and AI-driven molecular science.

🧪 Research papers that matter
🧠 structure–function insight
⚙️ Industry & biotech signals
💼 Jobs in protein design

Curated by me
📜
recep2244.github.io/portfolio/#n...

Recep Adiyaman | Bioinformatician

Bioinformatician specializing in Protein Structure Prediction and Molecular Dynamics

recep2244.github.io

January 4, 2026 at 1:03 AM

Recep Adiyaman

@recep44.bsky.social

It was an honor to meet Nobel Laureate John Jumper at ISMB/ECCB 2025 in Liverpool just before his distinguished keynote. We had a fascinating discussion about AlphaFold2, AlphaFold3, and the future of the field—truly inspiring! @instadeepai
@UniofReading @IntFOLD @JohnJumperSci #ismbeccb2025

July 21, 2025 at 3:28 AM

Reposted by Recep Adiyaman

IntFOLD

@intfold.bsky.social

Our new paper is out: Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers
academic.oup.com/nar/advance-...

Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers

Abstract. Understanding the structures of protein complexes is pivotal for breakthroughs in health, agriculture, bioengineering, and beyond. MultiFOLD2 and

academic.oup.com

April 28, 2025 at 8:54 AM

Reposted by Recep Adiyaman

Liam McGuffin

@liammcguffin.bsky.social

Yesterday at #CASP16 I presented our new ModFOLDdock2 servers for the quality assessment of multimer models. It's great to see progress in the field but there are still many challenges ahead!

December 3, 2024 at 1:43 PM

Reposted by Recep Adiyaman

Liam McGuffin

@liammcguffin.bsky.social

My group members, Shaima and @recep44.bsky.social, presented their posters on MultiFOLD2 for multimer modelling and FunFOLD5 for predicting protein-ligand interactions at #CASP16. Lots of interest and positive feedback!

December 3, 2024 at 1:47 PM

Reposted by Recep Adiyaman

Liam McGuffin

@liammcguffin.bsky.social

ModFOLDdock2 is the top ranked method for predicting the interface accuracy of modelled protein complexes #CASP16. The server is available here: www.reading.ac.uk/bioinf/ModFO...

December 3, 2024 at 3:37 PM

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