Rebecca Chen
@rebeccachen.bsky.social
PhD candidate @thehoffmanlab.bsky.social working on the genomics of sexual trait expression in black grouse 🧬👩💻🧪
mutation load | inbreeding | population genetics | ecological epigenetics | sexual selection
https://rshuhuachen.github.io/rc/
mutation load | inbreeding | population genetics | ecological epigenetics | sexual selection
https://rshuhuachen.github.io/rc/
Reposted by Rebecca Chen
DNA as street decoration? Of course! Our very own @k-hench.bsky.social made some beautiful pictures of the @eseb2025.bsky.social street decorations at the “Festes de Gràcia”.
Check out some of his pictures and read more about why we were there: thehoffmanlab.com/2025/09/05/e...
Check out some of his pictures and read more about why we were there: thehoffmanlab.com/2025/09/05/e...
ESEB 2025
Four of our lab members presented their work at the Congress of the European Society for Evolutionary Biology (ESEB 2025) in Barcelona in August. Beril presented a pilot study linked to her multi-p…
thehoffmanlab.com
September 5, 2025 at 12:27 PM
DNA as street decoration? Of course! Our very own @k-hench.bsky.social made some beautiful pictures of the @eseb2025.bsky.social street decorations at the “Festes de Gràcia”.
Check out some of his pictures and read more about why we were there: thehoffmanlab.com/2025/09/05/e...
Check out some of his pictures and read more about why we were there: thehoffmanlab.com/2025/09/05/e...
Reposted by Rebecca Chen
The genome and epigenome are not independent, so why analyse them separately? 🤔 Come and discuss our hypotheses on the interplay between deleterious mutations and epigenetic mechanisms today with @rebeccachen.bsky.social at #ESEB2025 poster number 85! 🧪🧬
August 21, 2025 at 8:33 AM
The genome and epigenome are not independent, so why analyse them separately? 🤔 Come and discuss our hypotheses on the interplay between deleterious mutations and epigenetic mechanisms today with @rebeccachen.bsky.social at #ESEB2025 poster number 85! 🧪🧬
Getting excited for @eseb2025.bsky.social next week! Come listen to my talk on mutation load published earlier this week in NEE (Tues 2 pm, meeting room 131), and/or chat with me about the interplay between deleterious mutations and epigenetics at poster session 3 (Thurs 5-7 pm, P03.085) 🔬🧬🐥
Working on mutation load, inbreeding or bottlenecks and attending ESEB2025 Congress of the European Society for Evolutionary Biology next week? Check out our lab's talks and posters 😁 Looking forward to chat with you!
August 15, 2025 at 8:59 AM
Getting excited for @eseb2025.bsky.social next week! Come listen to my talk on mutation load published earlier this week in NEE (Tues 2 pm, meeting room 131), and/or chat with me about the interplay between deleterious mutations and epigenetics at poster session 3 (Thurs 5-7 pm, P03.085) 🔬🧬🐥
The core chapter of my PhD has now been published in Nature E&E! 🧬🥳
In this paper, we investigate whether predicted deleterious mutations reduce fitness and if so, how? Do heterozygous mutations also contribute? And are non-coding mutations more deleterious?
Read all about it here: rdcu.be/eAcM5
In this paper, we investigate whether predicted deleterious mutations reduce fitness and if so, how? Do heterozygous mutations also contribute? And are non-coding mutations more deleterious?
Read all about it here: rdcu.be/eAcM5
Predicted deleterious mutations reveal the genetic architecture of male reproductive success in a lekking bird
Nature Ecology & Evolution - Analysis of whole genomes and life-history data of male black grouse shows that deleterious mutations, especially those in promotors, reduce lifetime reproductive...
rdcu.be
August 11, 2025 at 10:30 AM
The core chapter of my PhD has now been published in Nature E&E! 🧬🥳
In this paper, we investigate whether predicted deleterious mutations reduce fitness and if so, how? Do heterozygous mutations also contribute? And are non-coding mutations more deleterious?
Read all about it here: rdcu.be/eAcM5
In this paper, we investigate whether predicted deleterious mutations reduce fitness and if so, how? Do heterozygous mutations also contribute? And are non-coding mutations more deleterious?
Read all about it here: rdcu.be/eAcM5
Do you work on mutation load? 🔬🧬 Check out our new manuscript where we show that early-life viability selection primarily targets exonic mutations, in contrast to sexual selection which acts on mutations in promoters! 🧑🔬
Pre-print is available now: dx.doi.org/10.2139/ssrn... 🧪 #evolution #popgen
Pre-print is available now: dx.doi.org/10.2139/ssrn... 🧪 #evolution #popgen
Early-Life Viability Selection Targets Deleterious Mutations in Exons
Understanding how deleterious mutations affect fitness is fundamental to both evolutionary and conservation biology. However, most empirical studies rely on inb
dx.doi.org
July 31, 2025 at 1:47 PM
Do you work on mutation load? 🔬🧬 Check out our new manuscript where we show that early-life viability selection primarily targets exonic mutations, in contrast to sexual selection which acts on mutations in promoters! 🧑🔬
Pre-print is available now: dx.doi.org/10.2139/ssrn... 🧪 #evolution #popgen
Pre-print is available now: dx.doi.org/10.2139/ssrn... 🧪 #evolution #popgen
Reposted by Rebecca Chen
There is still lots of time to sign up for our 2025 edition of the #EvoBioCC 🥳💚✨
It is a FREE, online course in Evolutionary Biology, made by students and for students! Please share widely and don't forget to register! 💚💚💚
docs.google.com/forms/d/e/1F...
It is a FREE, online course in Evolutionary Biology, made by students and for students! Please share widely and don't forget to register! 💚💚💚
docs.google.com/forms/d/e/1F...
EvoBio Crash Course 2025 | Registration Form
The fourth edition of the EvoBio Crash Course has opened registration and we are very happy to have you! We are focusing on delivering a rich course on the basics of evolutionary biology so that stude...
docs.google.com
June 15, 2025 at 1:46 AM
There is still lots of time to sign up for our 2025 edition of the #EvoBioCC 🥳💚✨
It is a FREE, online course in Evolutionary Biology, made by students and for students! Please share widely and don't forget to register! 💚💚💚
docs.google.com/forms/d/e/1F...
It is a FREE, online course in Evolutionary Biology, made by students and for students! Please share widely and don't forget to register! 💚💚💚
docs.google.com/forms/d/e/1F...
Publication alert! ✨ Our recent paper in Ecology & Evolution addresses how to make conferences more inclusive. We collected observational and experimental data during Q&A sessions at the Behaviour 2023 congress hosted by Bielefeld University, and circulated a survey among conference attendees [1/4]
July 14, 2025 at 8:25 AM
Publication alert! ✨ Our recent paper in Ecology & Evolution addresses how to make conferences more inclusive. We collected observational and experimental data during Q&A sessions at the Behaviour 2023 congress hosted by Bielefeld University, and circulated a survey among conference attendees [1/4]
Reposted by Rebecca Chen
@anelivb.bsky.social & @rebeccachen.bsky.social emphasise the pre-publication error correction potential of open data in our latest #SORTEEjournal club post:
https://sortee.org/blog/2025/01/23/2025_on_open_science_error_correction_and_the_imperfect_scientist/
https://sortee.org/blog/2025/01/23/2025_on_open_science_error_correction_and_the_imperfect_scientist/
February 10, 2025 at 8:29 AM
@anelivb.bsky.social & @rebeccachen.bsky.social emphasise the pre-publication error correction potential of open data in our latest #SORTEEjournal club post:
https://sortee.org/blog/2025/01/23/2025_on_open_science_error_correction_and_the_imperfect_scientist/
https://sortee.org/blog/2025/01/23/2025_on_open_science_error_correction_and_the_imperfect_scientist/
Our preprint is out! We predicted deleterious mutations and reveal the genomic mechanisms underlying fitness variation in black grouse, a classic lekking bird. Check it out doi.org/10.21203/rs....
#genomics #popgen #genetics
#genomics #popgen #genetics
Predicted deleterious mutations reveal the genomic mechanisms underlying fitness variation in a lekking bird
Deleterious mutations are ubiquitous in natural populations and, when expressed, reduce fitness. However, the specific nature of these mutations and the mechanisms through which they impact fitness r...
doi.org
December 11, 2024 at 7:37 AM
Our preprint is out! We predicted deleterious mutations and reveal the genomic mechanisms underlying fitness variation in black grouse, a classic lekking bird. Check it out doi.org/10.21203/rs....
#genomics #popgen #genetics
#genomics #popgen #genetics