@rantao2023.bsky.social
Honored to contribute to this study! Excited to see the impact of our work.
Today in @nature.com we share our back-to-back stories with Ning Zheng’s lab revealing chemical-genetic convergence between a molecular glue degrader & E3 ligase cancer mutations. 1/5
February 13, 2025 at 6:07 AM
Honored to contribute to this study! Excited to see the impact of our work.
Thrilled to share our recent work published in @naturegenet.bsky.social, where we uncover how ZIC1 is regulated by distinct genetic and epigenetic mechanisms in SHH vs. Group 4 medulloblastoma—revealing it as a context-dependent driver. tinyurl.com/2c3jnhn2
ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip - Nature Genetics
Analysis of medulloblastomas in humans and mice shows that the functional consequences of ZIC1 mutations are exquisitely dependent on the cells of origin that give rise to different subgroups of medul...
tinyurl.com
January 7, 2025 at 3:05 PM
Thrilled to share our recent work published in @naturegenet.bsky.social, where we uncover how ZIC1 is regulated by distinct genetic and epigenetic mechanisms in SHH vs. Group 4 medulloblastoma—revealing it as a context-dependent driver. tinyurl.com/2c3jnhn2