Patrick Aloy
@ptck72.bsky.social
ICREA researcher @ IRB Barcelona
Blending biology, chemistry and AI to enable systems pharmacology
Blending biology, chemistry and AI to enable systems pharmacology
Super happy to present the systematic assessment of microenvironment-dependent transcriptional patters and intracellular communication carried out by @epareja10.bsky.social !
🔬 A new study by #IRBBarcelona reveals the limitations of current methods used to study cell communication.
📰 #GenomeBiology
✍️ @epareja10.bsky.social @ptck72.bsky.social
➡️ bit.ly/4kvcD2a
📌 DOI: 10.1186/s13059-025-03677-5
#IRBScience
🧪 🧵👇
📰 #GenomeBiology
✍️ @epareja10.bsky.social @ptck72.bsky.social
➡️ bit.ly/4kvcD2a
📌 DOI: 10.1186/s13059-025-03677-5
#IRBScience
🧪 🧵👇
July 10, 2025 at 9:58 AM
Super happy to present the systematic assessment of microenvironment-dependent transcriptional patters and intracellular communication carried out by @epareja10.bsky.social !
Reposted by Patrick Aloy
🔬A new computational protocol to explore bioactivity spaces and signatures, out now in @natprot.nature.com!
Researchers at #IRBBarcelona led by @ptck72.bsky.social present a comprehensive pipeline to integrate new bioactivity data into the #ChemicalChecker
Article ➡️ www.nature.com/articles/s41...
Researchers at #IRBBarcelona led by @ptck72.bsky.social present a comprehensive pipeline to integrate new bioactivity data into the #ChemicalChecker
Article ➡️ www.nature.com/articles/s41...
Integration of diverse bioactivity data into the Chemical Checker compound universe - Nature Protocols
The Chemical Checker is a collection of small-molecule bioactivity signatures organized in increasing levels of biological complexity. This protocol describes how to incorporate new data, create novel...
www.nature.com
May 29, 2025 at 8:30 AM
🔬A new computational protocol to explore bioactivity spaces and signatures, out now in @natprot.nature.com!
Researchers at #IRBBarcelona led by @ptck72.bsky.social present a comprehensive pipeline to integrate new bioactivity data into the #ChemicalChecker
Article ➡️ www.nature.com/articles/s41...
Researchers at #IRBBarcelona led by @ptck72.bsky.social present a comprehensive pipeline to integrate new bioactivity data into the #ChemicalChecker
Article ➡️ www.nature.com/articles/s41...
Excellent work, @jsvanleeuwen.bsky.social !!
Some science news to brighten up your timelines ☀️ Our latest work on the modifiers that cause changes in gene essentiality between genetic backgrounds, now on bioRxiv: www.biorxiv.org/content/10.1...
So what did we find?
So what did we find?
The modifiers that cause changes in gene essentiality
www.biorxiv.org
March 9, 2025 at 9:44 PM
Excellent work, @jsvanleeuwen.bsky.social !!