Profolus
@profolus.com
Explainers on business and markets, science and tech, health and medicine, and society and culture. www.profolus.com
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Profolus
@profolus.com
· Sep 3
Recent polls following the first couple of months of Donald Trump in office indicate he is on his way to becoming the most hated U.S. president at first-year mark in U.S. history.
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2025 HIGHLIGHT: Many human genes share conserved counterparts in nematodes, enabling simulation of pathogenic variation. Each engineered worm acts as an avatar reflecting molecular consequences detected in human patients.
How Tiny Worms Are Becoming Avatars for Human Patients in Drug Research - Profolus
Behavioral tracking in Caenorhabditis elegans enables high throughput identification of treatment candidates for ultra rare diseases.
www.profolus.com
December 25, 2025 at 9:30 PM
2025 HIGHLIGHT: Many human genes share conserved counterparts in nematodes, enabling simulation of pathogenic variation. Each engineered worm acts as an avatar reflecting molecular consequences detected in human patients.
The U.S. dollar has been the dominant currency of the world since the Bretton Woods Agreement of 1944 established it as the reserve currency and considering how the U.S. became the largest and most stable economy in the world after World War II.
How U.S. Dollar Dominance Contributes to U.S. Trade Deficit - Profolus
The U.S. dollar has been the dominant currency of the world. This status contributes to the persistent U.S. trade deficit.
www.profolus.com
December 25, 2025 at 9:00 PM
The U.S. dollar has been the dominant currency of the world since the Bretton Woods Agreement of 1944 established it as the reserve currency and considering how the U.S. became the largest and most stable economy in the world after World War II.
AI has a secret thirst that tech companies rarely disclose. A new methodology for estimating the current water footprint of AI reveals that the total water consumption of AI data centers is now comparable to the entire annual global demand for bottled water.
AI Water Use In 2025 Rivals Global Bottled Water Demand - Profolus
Most AI-related water consumption occurs far from servers.
www.profolus.com
December 25, 2025 at 8:30 PM
AI has a secret thirst that tech companies rarely disclose. A new methodology for estimating the current water footprint of AI reveals that the total water consumption of AI data centers is now comparable to the entire annual global demand for bottled water.
Think your local environmental laws are keeping you safe? Think again. The global seafood trade is acting as a "planetary conveyor belt" that ships the notorious "forever chemicals" from industrial hotspots directly to your dinner table.
How the Global Fish Trade Spreads Forever Chemicals - Profolus
Forever chemicals or PFAS are traveling the world through the global seafood trade.
www.profolus.com
December 25, 2025 at 8:00 PM
Think your local environmental laws are keeping you safe? Think again. The global seafood trade is acting as a "planetary conveyor belt" that ships the notorious "forever chemicals" from industrial hotspots directly to your dinner table.
2025 HIGHLIGHT: Diella, which means Sun in Albanian, first appeared in January 2025 as a virtual assistant within the e-Albania digital services. Its functions are set to expand into procurement decision making.
Meet Diella: Albania Becomes First Nation to Appoint an AI Minister - Profolus
Albania appoints Diella, the first artificial intelligence minister in the world, to eliminate corruption in public tenders.
www.profolus.com
December 25, 2025 at 7:30 PM
2025 HIGHLIGHT: Diella, which means Sun in Albanian, first appeared in January 2025 as a virtual assistant within the e-Albania digital services. Its functions are set to expand into procurement decision making.
One of the most popular lore about domestic cats involves a newborn Jesus Christ kept warm by a random cat. Mary later marked its forehead with her initials as a token of gratitude.
The Science Behind the “M” Marking on a Cat’s Forehead - Profolus
All tabby cats have the "M" marking on their foreheads. Even some non-tabbies also feature a faint "M" marking.
www.profolus.com
December 25, 2025 at 7:00 PM
One of the most popular lore about domestic cats involves a newborn Jesus Christ kept warm by a random cat. Mary later marked its forehead with her initials as a token of gratitude.
2025 HIGHLIGHT: The September 2025 report marks the first time a U.N. investigative body has declared that the military campaign of Israel in the Gaza Strip constitutes genocide under the Genocide Convention framework.
United Nations Commission Investigation: Israel Has Committed Genocide in Gaza - Profolus
An independent UN investigation found that the campaign of Israel in Gaza constitutes genocide under international law.
www.profolus.com
December 25, 2025 at 6:30 PM
2025 HIGHLIGHT: The September 2025 report marks the first time a U.N. investigative body has declared that the military campaign of Israel in the Gaza Strip constitutes genocide under the Genocide Convention framework.
Historical Germanic people, including the Anglo-Saxons and followers of the Norse paganism, observed a winter festival called the Yule or Yuletide from late December to early January.
The Pagan Origins of Christmas - Profolus
A brief discussion of the pagan origins of Christmas, including pagan customs incorporated in modern Christmas celebration.
www.profolus.com
December 25, 2025 at 6:00 PM
Historical Germanic people, including the Anglo-Saxons and followers of the Norse paganism, observed a winter festival called the Yule or Yuletide from late December to early January.
Whenever individuals or institutions, including government officials, blame the distant past for the poor performance of specific stocks or the entire stock index, it signals an attempt to deflect from responsibility and shift blame away from current leadership.
Stock Market: Always Reactive, Somewhat Proactive, But Rarely Retroactive - Profolus
The stock market lives in the present and it keeps an eye on the future. It also occasionally glances at the past.
www.profolus.com
December 25, 2025 at 5:30 PM
Whenever individuals or institutions, including government officials, blame the distant past for the poor performance of specific stocks or the entire stock index, it signals an attempt to deflect from responsibility and shift blame away from current leadership.
The best performers in the world were often unremarkable as children. A large review finds that early success predicts little about adult excellence, while broad experience, delayed specialization, and steady improvement matter far more.
Early Prodigies Rarely Succeed As Adults But Most Late Bloomers Excel - Profolus
Most best performers in the world were often unremarkable as children.
www.profolus.com
December 25, 2025 at 5:00 PM
The best performers in the world were often unremarkable as children. A large review finds that early success predicts little about adult excellence, while broad experience, delayed specialization, and steady improvement matter far more.
2025 HIGHLIGHT: Albania has taken an unprecedented step by appointing the artificial intelligence entity Diella as what has been described as a minister.
Meet Diella: Albania Becomes First Nation to Appoint an AI Minister - Profolus
Albania appoints Diella, the first artificial intelligence minister in the world, to eliminate corruption in public tenders.
www.profolus.com
December 25, 2025 at 7:30 AM
2025 HIGHLIGHT: Albania has taken an unprecedented step by appointing the artificial intelligence entity Diella as what has been described as a minister.
A particular executive order of the second Trump administration outlines a federal strategy to prevent states from enforcing independent AI regulations. Rather than voiding laws directly, it relies on litigation, funding pressure, and federal standards.
How the Trump Executive Order Plans to Block State AI Regulation - Profolus
The executive order positions artificial intelligence as a matter of interstate commerce and national security.
www.profolus.com
December 25, 2025 at 7:15 AM
A particular executive order of the second Trump administration outlines a federal strategy to prevent states from enforcing independent AI regulations. Rather than voiding laws directly, it relies on litigation, funding pressure, and federal standards.
While the dominance of the U.S. dollar has afforded both the American economy and government several advantages and privileges, it also contributes to the persistent U.S. trade deficit.
How U.S. Dollar Dominance Contributes to U.S. Trade Deficit - Profolus
The U.S. dollar has been the dominant currency of the world. This status contributes to the persistent U.S. trade deficit.
www.profolus.com
December 25, 2025 at 7:00 AM
While the dominance of the U.S. dollar has afforded both the American economy and government several advantages and privileges, it also contributes to the persistent U.S. trade deficit.
2025 HIGHLIGHT: The Independent International Commission of Inquiry on the Occupied Palestinian Territory of the Human Rights Council of the United Nations has concluded that the military campaign of Israel in the Gaza Strip constitutes genocide.
United Nations Commission Investigation: Israel Has Committed Genocide in Gaza - Profolus
An independent UN investigation found that the campaign of Israel in Gaza constitutes genocide under international law.
www.profolus.com
December 25, 2025 at 6:45 AM
2025 HIGHLIGHT: The Independent International Commission of Inquiry on the Occupied Palestinian Territory of the Human Rights Council of the United Nations has concluded that the military campaign of Israel in the Gaza Strip constitutes genocide.
Researchers have identified small household appliances, such as air friers, toasters, and hair dryers, as significant sources of ultrafine particles. These invisible pollutants can reach concentrations 10 to 100 times higher than typical indoor levels.
Electric Home Appliances Emit Trillions Of Ultrafine Particles - Profolus
A study highlights indoor air pollution as an underappreciated health issue linked to everyday technology.
www.profolus.com
December 25, 2025 at 6:30 AM
Researchers have identified small household appliances, such as air friers, toasters, and hair dryers, as significant sources of ultrafine particles. These invisible pollutants can reach concentrations 10 to 100 times higher than typical indoor levels.
KONSYSE: Trump's executive directs the executive branch to fast-track the reclassification of marijuana and expands the framework for CBD research and access. It reclassified marijuana from Schedule I to Schedule III under the Controlled Substances Act.
Why Trump Signs EO to Fast-Track Marijuana Schedule III Reclassification — Konsyse
U.S. President Trump signed the "Increasing Medical Marijuana and Cannabidiol Research" executive order.
www.konsyse.com
December 25, 2025 at 6:15 AM
KONSYSE: Trump's executive directs the executive branch to fast-track the reclassification of marijuana and expands the framework for CBD research and access. It reclassified marijuana from Schedule I to Schedule III under the Controlled Substances Act.
2025 HIGHLIGHT: Researchers at Oregon Health and Science University have engineered a striking proof of concept. They were able to convert human skin cell nuclei into functional egg cells that can be fertilized.
Mitomeiosis: Scientists Made Human Egg Cells From Skin Cells - Profolus
Scientists have converted human skin cells into functional eggs using a new process called mitomeiosis.
www.profolus.com
December 25, 2025 at 6:00 AM
2025 HIGHLIGHT: Researchers at Oregon Health and Science University have engineered a striking proof of concept. They were able to convert human skin cell nuclei into functional egg cells that can be fertilized.
In acknowledging the impacts of an uncontrolled outbreak, world powers, including the United States government, have taken prevention and containment measures, even if a particular outbreak is occurring in a distant continent.
The Importance of Global Ebola Prevention Efforts - Profolus
Various state and non-state actors have taken measures to prevent or control Ebola outbreaks—even if one is occurring in a distant continent.
www.profolus.com
December 25, 2025 at 5:45 AM
In acknowledging the impacts of an uncontrolled outbreak, world powers, including the United States government, have taken prevention and containment measures, even if a particular outbreak is occurring in a distant continent.
The “M” marking on the foreheads of cats has inspired several legends across different cultures. One of the most popular lores involves a newborn Jesus Christ kept warm by a random cat. Mary later marked its forehead with her initials as a token of gratitude.
The Science Behind the “M” Marking on a Cat’s Forehead - Profolus
All tabby cats have the "M" marking on their foreheads. Even some non-tabbies also feature a faint "M" marking.
www.profolus.com
December 25, 2025 at 5:30 AM
The “M” marking on the foreheads of cats has inspired several legends across different cultures. One of the most popular lores involves a newborn Jesus Christ kept warm by a random cat. Mary later marked its forehead with her initials as a token of gratitude.
2025 HIGHLIGHT: During his first appearance in the cabinet meeting of the Trump administration, Elon Musk admitted that they accidentally halted all funding related to Ebola prevention efforts while gutting the budget of USAID.
Elon Musk: DOGE Gutted Ebola Efforts. Here's What Happened and Its Impact - Profolus
Elon Musk admitted that his DOGE staffers "accidentally" halted funding related to Ebola prevention efforts while gutting USAID budget.
www.profolus.com
December 25, 2025 at 5:15 AM
2025 HIGHLIGHT: During his first appearance in the cabinet meeting of the Trump administration, Elon Musk admitted that they accidentally halted all funding related to Ebola prevention efforts while gutting the budget of USAID.
The platform, described as an artificial intelligence-generated encyclopedia powered by Grok, aims to offer a truthful alternative to Wikipedia while promising factual independence and ideological balance.
Grokipedia Review: Advantages and Disadvantages - Profolus
Grokipedia is a bold AI experiment from Elon Musk that aims to replace Wikipedia and reinvent online knowledge.
www.profolus.com
December 25, 2025 at 5:00 AM
The platform, described as an artificial intelligence-generated encyclopedia powered by Grok, aims to offer a truthful alternative to Wikipedia while promising factual independence and ideological balance.
English anthropologist Sir Edward Burnett Taylor explained that one hypothesis about the origins of Christmas argued that the modern date of the festivity was intentionally chosen to coincide the founding of the Sol Invictus cult.
The Pagan Origins of Christmas - Profolus
A brief discussion of the pagan origins of Christmas, including pagan customs incorporated in modern Christmas celebration.
www.profolus.com
December 25, 2025 at 4:45 AM
English anthropologist Sir Edward Burnett Taylor explained that one hypothesis about the origins of Christmas argued that the modern date of the festivity was intentionally chosen to coincide the founding of the Sol Invictus cult.
2025 HIGHLIGHT: A simple water-based process turned a common tin compound into ultrathin flakes that generate intense cancer-killing heat when illuminated using LED light.
Tiny Heat-Generating Flakes Target Cancer When Exposed to LED Light - Profolus
A green fabrication process and 810-nm LED illumination show how safer chemistry and accessible tools could reshape photothermal cancer therapy.
www.profolus.com
December 25, 2025 at 4:30 AM
2025 HIGHLIGHT: A simple water-based process turned a common tin compound into ultrathin flakes that generate intense cancer-killing heat when illuminated using LED light.
Dr. Amy H. Herring and her team conducted a national longitudinal study that ran from 1995 to 2009. Findings revealed that 0.5 percent of the pregnancies that occurred in the surveyed group allegedly transpired despite the absence of sexual intercourse.
Study: The Case of Virgin Births in the United States - Profolus
There appears to be an explosion of virgin births in the U.S. based on a 2013 study. An analysis of the data revealed an interesting insight.
www.profolus.com
December 25, 2025 at 4:00 AM
Dr. Amy H. Herring and her team conducted a national longitudinal study that ran from 1995 to 2009. Findings revealed that 0.5 percent of the pregnancies that occurred in the surveyed group allegedly transpired despite the absence of sexual intercourse.
2025 HIGHLIGHT: Elon Musk, during his first appearance in the cabinet meeting of the Trump administration, admitted that DODGE accidentally halted all funding related to Ebola prevention efforts while gutting USAID budget.
Elon Musk: DOGE Gutted Ebola Efforts. Here's What Happened and Its Impact - Profolus
Elon Musk admitted that his DOGE staffers "accidentally" halted funding related to Ebola prevention efforts while gutting USAID budget.
www.profolus.com
December 24, 2025 at 9:00 PM
2025 HIGHLIGHT: Elon Musk, during his first appearance in the cabinet meeting of the Trump administration, admitted that DODGE accidentally halted all funding related to Ebola prevention efforts while gutting USAID budget.