Prachiti Moghe
prachitimoghe.bsky.social
Prachiti Moghe
@prachitimoghe.bsky.social
Postdoc in the Roska Lab at IOB Basel
Previously PhD in the Hiiragi Lab @EMBL @HubrechtInstitute
How do embryos develop robustly despite variability in gene expression, cell properties, and tissue growth? In our new review, we explore how optimal selection of coupled parameters can contribute to robustness in development. Have a look at the article:
doi.org/10.1016/j.tc...
Redirecting
doi.org
October 10, 2025 at 8:18 AM
Reposted by Prachiti Moghe
How do cells find their place in a developing embryo? Scientists have long wondered. A new study by the Hiiragi group uncovers how embryos achieve precise cell organization. Curious what breadcrumbs have to do with this? @prachitimoghe.bsky.social explains it here: www.hubrecht.eu/breadcrumb-t...
February 18, 2025 at 10:24 AM
Delighted to share that my PhD work from the Hiiragi Lab is now published in Nature Cell Biology! We uncover the cellular mechanisms underlying pattern formation and how patterning robustness can be ensured during embryo development. Check out the full story: nature.com/articles/s41556-025-01618-9
Coupling of cell shape, matrix and tissue dynamics ensures embryonic patterning robustness - Nature Cell Biology
Moghe et al. show that mouse embryonic primitive endoderm cells migrate towards the inner cell mass-cavity interface, depositing an extracellular matrix gradient that may guide migration. Primitive en...
nature.com
February 18, 2025 at 10:07 AM