Pobezinsky Lab
pobezinskylab.bsky.social
Pobezinsky Lab
@pobezinskylab.bsky.social
T cell responses, formation of immunological memory. Tumor immunology and infection.
Reposted by Pobezinsky Lab
A Dapl1+ subpopulation of naïve CD8 T cells is enriched for memory-lineage precursors | Science Advances www.science.org/doi/10.1126/...

Our new story just came out in Science Advances! So proud of Adam Lynch and the rest of our team.
A Dapl1+ subpopulation of naïve CD8 T cells is enriched for memory-lineage precursors
Thymic-derived naïve Dapl1+ CD8 T cells contain a subset preprogrammed to form memory-like cells upon activation.
www.science.org
August 22, 2025 at 7:11 PM
Reposted by Pobezinsky Lab
We’re excited to present this integrative analysis of single-cell proteomics and transcriptomics of the human HSPC hierarchy. Now published in @science.org together with @fabiantheis.bsky.social, @erwinschoof.bsky.social, @porsebo.bsky.social.
www.science.org/doi/10.1126/...
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Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics
Single-cell transcriptomics (scRNA-seq) has facilitated the characterization of cell state heterogeneity and recapitulation of differentiation trajectories. However, the exclusive use of mRNA measurem...
www.science.org
August 22, 2025 at 6:03 AM
A Dapl1+ subpopulation of naïve CD8 T cells is enriched for memory-lineage precursors | Science Advances www.science.org/doi/10.1126/...

Our new story just came out in Science Advances! So proud of Adam Lynch and the rest of our team.
A Dapl1+ subpopulation of naïve CD8 T cells is enriched for memory-lineage precursors
Thymic-derived naïve Dapl1+ CD8 T cells contain a subset preprogrammed to form memory-like cells upon activation.
www.science.org
August 22, 2025 at 7:11 PM