Pliotas Group
@pliotasgroup.bsky.social
Mechanosensitive channels & Membrane Proteins - Structural EPR Spectroscopy at The University of Manchester - DEER/PELDOR/PDS
pliotasgroup.org
pliotasgroup.org
We have a new academic post opening for a Lecture/Senior-Lecturer in Structural Biology @mcf-uom.bsky.social @fbmh-uom.bsky.social @manchester.ac.uk The University of Manchester is ranked among the top Universities worldwide. QS world rankings: 34th (2025)
www.jobs.manchester.ac.uk/Job/JobDetai...
www.jobs.manchester.ac.uk/Job/JobDetai...
Lecturer / Senior Lecturer in Structural Biology:Oxford Road
The purpose of this post is to undertake high quality research and also excellent teaching. Hence, the ability to enhance teaching activities within our UG/PG programmes will also be expected.
www.jobs.manchester.ac.uk
October 28, 2025 at 11:07 AM
We have a new academic post opening for a Lecture/Senior-Lecturer in Structural Biology @mcf-uom.bsky.social @fbmh-uom.bsky.social @manchester.ac.uk The University of Manchester is ranked among the top Universities worldwide. QS world rankings: 34th (2025)
www.jobs.manchester.ac.uk/Job/JobDetai...
www.jobs.manchester.ac.uk/Job/JobDetai...
Reposted by Pliotas Group
Congratulations to Maria Chiara Pagliero and Anand Anilkumar who were the winners of the IEPRS Poster Prizes awarded from the International EPR Society at the 10th EFEPR Summer School at The University of Manchester
@officialuom.bsky.social
@officialuom.bsky.social
September 12, 2025 at 11:10 AM
Congratulations to Maria Chiara Pagliero and Anand Anilkumar who were the winners of the IEPRS Poster Prizes awarded from the International EPR Society at the 10th EFEPR Summer School at The University of Manchester
@officialuom.bsky.social
@officialuom.bsky.social
In our study @elife.bsky.social we uncover the mechanism of mPPase inhibition. Over 20x structures to date are in a symmetric form. We use EPR(PELDOR/DEER) and reveal asymmetric binding at the active site while maintaining symmetric conformation at periplasmic site
elifesciences.org/reviewed-pre...
elifesciences.org/reviewed-pre...
July 15, 2025 at 1:44 PM
In our study @elife.bsky.social we uncover the mechanism of mPPase inhibition. Over 20x structures to date are in a symmetric form. We use EPR(PELDOR/DEER) and reveal asymmetric binding at the active site while maintaining symmetric conformation at periplasmic site
elifesciences.org/reviewed-pre...
elifesciences.org/reviewed-pre...
Reposted by Pliotas Group
@Bruker's ELEXSYS E580Q Spectrometer has found its new home at the University of Manchester (@OfficialUoM)!
Watch as an empty lab is turned into a cutting-edge #EPR lab & hear from Prof. Christos Pliotas, who leads the research group driving innovation.
👉 youtu.be/Hz4fCqh8PeY [youtu.be]
Watch as an empty lab is turned into a cutting-edge #EPR lab & hear from Prof. Christos Pliotas, who leads the research group driving innovation.
👉 youtu.be/Hz4fCqh8PeY [youtu.be]
ELEXSYS E580Q Spectrometer Installation, BioEmPiRe Centre for Structural Biological EPR Spectroscopy
YouTube video by Bruker
youtu.be
May 14, 2025 at 11:41 AM
@Bruker's ELEXSYS E580Q Spectrometer has found its new home at the University of Manchester (@OfficialUoM)!
Watch as an empty lab is turned into a cutting-edge #EPR lab & hear from Prof. Christos Pliotas, who leads the research group driving innovation.
👉 youtu.be/Hz4fCqh8PeY [youtu.be]
Watch as an empty lab is turned into a cutting-edge #EPR lab & hear from Prof. Christos Pliotas, who leads the research group driving innovation.
👉 youtu.be/Hz4fCqh8PeY [youtu.be]
Reposted by Pliotas Group
Wednesday, April 23, 9 am EDT / 3 pm CEST, IVEM webinar, Christos Pliotas @pliotasgroup.bsky.social University of Manchester, Accessing uncharted membrane protein ensembles by structural biological EPR spectroscopy www.eprseminars.org #NMRchat #NMR #EPR #ESR 🧲 🧪
April 16, 2025 at 7:21 PM
Wednesday, April 23, 9 am EDT / 3 pm CEST, IVEM webinar, Christos Pliotas @pliotasgroup.bsky.social University of Manchester, Accessing uncharted membrane protein ensembles by structural biological EPR spectroscopy www.eprseminars.org #NMRchat #NMR #EPR #ESR 🧲 🧪
Reposted by Pliotas Group
2025 IES John Weil Young Investigator Award: Nino Wili his outstanding contributions to theory and instrumentation in the field of EPR spectroscopy.
March 17, 2025 at 3:21 PM
2025 IES John Weil Young Investigator Award: Nino Wili his outstanding contributions to theory and instrumentation in the field of EPR spectroscopy.
Reposted by Pliotas Group
2025 IES Medal in Biology/Medicine: awarded to Olav Schiemann for his seminal contributions advancing the field of EPR in Biology via his pioneering efforts to resolve structural aspects of spin labelled nucleic acids and proteins.
March 17, 2025 at 3:22 PM
2025 IES Medal in Biology/Medicine: awarded to Olav Schiemann for his seminal contributions advancing the field of EPR in Biology via his pioneering efforts to resolve structural aspects of spin labelled nucleic acids and proteins.
Reposted by Pliotas Group
Early-career fellowships at the University of Manchester!
To celebrate 200 years of The University of Manchester, the Faculty of Biology Medicine and Health offers a 3-year Postdoctoral Fellowship to support exceptional early-career researchers:
www.bmh.manchester.ac.uk/research/sup...
To celebrate 200 years of The University of Manchester, the Faculty of Biology Medicine and Health offers a 3-year Postdoctoral Fellowship to support exceptional early-career researchers:
www.bmh.manchester.ac.uk/research/sup...
Bicentenary Early Career Research Fellowships | Biology, Medicine and Health | University of Manchester
Find out about and apply for a Bicentenary Early Career Research Fellowship.
www.bmh.manchester.ac.uk
March 4, 2025 at 9:21 PM
Early-career fellowships at the University of Manchester!
To celebrate 200 years of The University of Manchester, the Faculty of Biology Medicine and Health offers a 3-year Postdoctoral Fellowship to support exceptional early-career researchers:
www.bmh.manchester.ac.uk/research/sup...
To celebrate 200 years of The University of Manchester, the Faculty of Biology Medicine and Health offers a 3-year Postdoctoral Fellowship to support exceptional early-career researchers:
www.bmh.manchester.ac.uk/research/sup...
Reposted by Pliotas Group
Apply now for the 10th EFEPR Summer School in Manchester, UK, 31st Aug – 6th Sept 2025.
Attendees will receive training in advanced EPR theory & methods including hands on practical sessions. chemistry.manchester.ac.uk/epr/connect/... Expression of interest deadline: 21st Mar 2025
Attendees will receive training in advanced EPR theory & methods including hands on practical sessions. chemistry.manchester.ac.uk/epr/connect/... Expression of interest deadline: 21st Mar 2025
Events - EPSRC National Service for Electron Paramagnetic Resonance Spectroscopy - The University of Manchester
chemistry.manchester.ac.uk
March 3, 2025 at 3:19 PM
Apply now for the 10th EFEPR Summer School in Manchester, UK, 31st Aug – 6th Sept 2025.
Attendees will receive training in advanced EPR theory & methods including hands on practical sessions. chemistry.manchester.ac.uk/epr/connect/... Expression of interest deadline: 21st Mar 2025
Attendees will receive training in advanced EPR theory & methods including hands on practical sessions. chemistry.manchester.ac.uk/epr/connect/... Expression of interest deadline: 21st Mar 2025
In our recent article we show the YbiO mechanosensitive channel can achieve pore openings of 3nS under membrane tension equalling the largest known gated-pore MscL and we also solve a cryo- EM structure of a YbiO in a sub-open state. Great effort by @lane-b.bsky.social www.cell.com/structure/fu...
The mechanosensitive channel YbiO has a conductance equivalent to the largest gated-pore
Lane et al. demonstrate that the mechanosensitive channel YbiO can achieve conductances
equivalent to the largest gated-pore in nature when subjected to membrane tension.
Single-channel analysis shows...
www.cell.com
February 10, 2025 at 9:49 PM
In our recent article we show the YbiO mechanosensitive channel can achieve pore openings of 3nS under membrane tension equalling the largest known gated-pore MscL and we also solve a cryo- EM structure of a YbiO in a sub-open state. Great effort by @lane-b.bsky.social www.cell.com/structure/fu...
We reviewed recent pulsed EPR Spectroscopy (PELDOR/DEER/PDS) applications on integral membrane proteins, enabled through Spin Labelling. Great to see the field moving forward!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
February 2, 2025 at 6:12 PM
We reviewed recent pulsed EPR Spectroscopy (PELDOR/DEER/PDS) applications on integral membrane proteins, enabled through Spin Labelling. Great to see the field moving forward!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
New starter pack on EPR - ESR spectroscopy: go.bsky.app/KJZ4P8X
January 24, 2025 at 12:32 AM
New starter pack on EPR - ESR spectroscopy: go.bsky.app/KJZ4P8X