Polina Lishko
physiologyiscool.bsky.social
Polina Lishko
@physiologyiscool.bsky.social
Physiologist/reproductive biologist/biophysicist. Ion channels are cool! Views are my own.
Happy to share our latest work on ion channels, published in @natcomms.nature.com. Want to know why testes are external & cool? Nature has evolved a precise system to ensure that sperm are primed for fertilization at the right time. Tour de force work by Dr. Dilip Swain and our team: rdcu.be/eh9W7
The essential calcium channel of sperm CatSper is temperature-gated
Nature Communications - Here they show that the essential sperm calcium channel CatSper is temperature-gated and reversibly inhibited by spermine. This discovery uncovers a key regulatory mechanism...
rdcu.be
April 19, 2025 at 1:40 AM
congratulations to
@alanbrownhms.bsky.social lab, Rui Zhang lab @ruizhangmt.bsky.social and Qingwei Niu
@qingweiniu.bsky.social!
Another wonderful collaboration with @alanbrownhms.bsky.social lab 👇
Zhang lab (co-first author @qingweiniu.bsky.social) contribute the doublet structure from Crithidia fasciculata, a model organism that infects mosquitoes.
I am super excited to share our latest work on the structures of doublet microtubules from trypanosomatid parasites, the causative agents of leishmaniasis, Chagas disease, and African sleeping sickness. tinyurl.com/48sh3xn5
March 14, 2025 at 10:28 PM
Thrilled to share that our 4 years of hard work is finally published in Science Advances! 🚀🎉
Huge congratulations to the dream team:
@monikahaoui, Citlalli Vergara, and our fantastic colleagues from the Marc Spehr group www.science.org/doi/10.1126/...
Kir7.1 is the physiological target for hormones and steroids that regulate uteroplacental function
Progesterone and progestins activate Kir7.1 to control uterine excitability, offering insights for preterm birth therapy.
www.science.org
March 7, 2025 at 1:29 AM