Neural mechanisms underlying flexible learning and decision-making are not fully understood. Using single-cell calcium imaging, authors here found that neurons in orbitofrontal and secondary motor cortex exhibit complementary roles in reward learning, with neurons in the former exerting a sustained role in conditions of uncertainty.

Individuals differ drastically in whether they will cease actions with negative consequences. Using a specially-designed task, we explore the psychological roots for these differences, its stability a...

UNSW researchers uncover why some people persist in harmful behaviours – even when they’ve been shown where they’re going wrong.

Using a gamified punishment task, this study identifies specific learning and decision-making deficits that drive robust, consequential differences in choice within an international, general populatio...