perlstein.bsky.social
@perlstein.bsky.social
New paper alert! We ID resides of CIA targeting complex that recruit clients - in contradiction to what was predicted from previous studies, we find it is the cia1-cia2 interface, not cia1 on its own, that mediates the interaction.

pubs.acs.org/doi/10.1021/...
A Conserved Cia1–Cia2 Interface Mediates Client Recruitment in the Cytosolic Iron–Sulfur Cluster Assembly Pathway
The cytosolic iron–sulfur cluster assembly (CIA) targeting complex maturates over 30 cytosolic and nuclear Fe–S proteins, raising the question of how a single complex recognizes such a diverse set of ...
pubs.acs.org
September 19, 2025 at 12:53 AM
So, I have been learning about machine learning - if you want to learn with me, see our recently published article! Many thanks to all the trainees who wrote and edited this mammoth of a book chapter and the reviewers for their effort.
Check it out!
doi.org/10.1002/cpz1...
Getting Started with Machine Learning for Experimental Biochemists and Other Molecular Scientists
Machine learning (ML) is rapidly gaining traction in many areas of experimental molecular science for elucidating relationships and patterns in large or complex data sets. Historically, ML was largel....
doi.org
April 21, 2025 at 11:53 AM
Thank you to Amit Reddi and Sabeeha Merchant for invitation to speak at your metals-focused symposium at #ASBMB25. I had a great time and learned so much!
April 16, 2025 at 12:57 AM
Reposted
Great news: NIH postbac program is recruiting again! If your grad school plans were affected by program cutbacks or admissions freezes this year I highly encourage you to apply, this could be a perfect opportunity. Please repost.

www.training.nih.gov/research-tra...
www.training.nih.gov
April 10, 2025 at 1:22 AM
Reposted
NSF GRFP Awards by the Year:
2021 - 2074
2022 - 2193
2023 - 2555
2024 - 2036
2025 - 1000

Again, these funding cuts will have drastic longterm effects on the scientific future of the US.......

@jeremymberg.bsky.social @altnih4science.bsky.social
April 8, 2025 at 9:59 AM
Reposted
We are excited to announce our official partnership with @indivisible.org for the National Day of Action on April 5th!

Stand Up for Science says: HANDS OFF OUR SCIENCE!

#standupforscience
#handsoffourscience

Find and register for an event near you: handsoff2025.com?utm_source=s...
March 29, 2025 at 1:16 PM
I am one week late in posting my most sincere congratulations to Jackson Ho - the perlstein lab's newest PhD! He boldly tangled with the cytosolic Fe-S assembly factor Nar1/CIOA3, collecting first evidence for its cluster trafficking function.
March 29, 2025 at 7:55 PM
So excited to get this work out there! We have been working hard to "crack the CIA code" - more to come soon!
www.biorxiv.org/content/10.1...
The Cia1 and Cia2 subunits of the CTC mediate recognition of apo-FeS proteins with a C-terminal targeting complex recognition motif
The cytosolic iron-sulfur cluster assembly (CIA) targeting complex is responsible for maturation of cytosolic and nuclear iron-sulfur enzymes, numbering >30 proteins critical for fundamental processes...
www.biorxiv.org
March 27, 2025 at 11:49 AM
Don't miss Anastasiya's talk at #ACSspring2025 yall! it is going to be FANTASTIC! So proud to be (former) PI of this Emergent Leader - watch out world! Lets go!
March 11, 2025 at 5:46 PM
Standupforscience DC - here for a family thing - here for science
March 8, 2025 at 2:09 AM
Reposted
Welcome to the Bluesky account for Stand Up for Science 2025!

Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!

#scienceforall #sciencenotsilence
February 12, 2025 at 5:04 PM
Reposted
A small positive post in the midst of these uncertain times...
The Molecular Biology & Biochemistry department at Wesleyan is hiring a visiting professor for a Sept start date. Come join us and/or share with prospective applicants!
wesleyan.wd5.myworkdayjobs.com/careers/job/...
Visiting Professor of Molecular Biology and Biochemistry
Wesleyan University’s Department of Molecular Biology and Biochemistry invites applications for a full-time Visiting Professor in Molecular Biology and Biochemistry beginning September 1, 2025. The in...
wesleyan.wd5.myworkdayjobs.com
February 18, 2025 at 9:07 PM
Boston University Department of Chemistry is looking for 4 (four!) postdoctoral associate teacher scholars. These mentored teaching and research experiences aim to prepare future faculty ready to step into teaching focused roles.

Please repost and apply!

academicjobsonline.org/ajo/jobs/29703
Boston University, BU Chemistry
Full service online faculty recruitment and application management system for academic institutions worldwide. We offer unique solutions tailored for academic communities.
academicjobsonline.org
February 13, 2025 at 12:03 PM
Boston University is searching for up to 4 Post-Doctoral Teacher Scholars. These unique positions provide mentored teaching and research experiences to train next generation of professors for PUIs. Please reach out if you want more info!
academicjobsonline.org/ajo/jobs/29703
Boston University, BU Chemistry
Full service online faculty recruitment and application management system for academic institutions worldwide. We offer unique solutions tailored for academic communities.
academicjobsonline.org
February 7, 2025 at 3:46 PM
Had a little party today to welcome a new group member- not a bad Friday the 13th!
December 14, 2024 at 12:25 AM