Partnership for Clean Competition
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pccantidoping.bsky.social
Partnership for Clean Competition
@pccantidoping.bsky.social
We support analytical/social scientists doing anti-doping research via grants, postdoctoral fellowships, tech transfer, & working groups. PIs worldwide may apply.
Time matters when an #antidoping lab has to process 100s or 1,000s of samples quickly for large sporting events. Biotage is innovating their products to increase efficiency and address customers' needs. Learn more from Esraa AboJasser & Dr. Lee Williams.

cleancompetition.org/anti-doping-podcast/161
November 11, 2025 at 9:06 PM
Electroceuticals like spinal cord stimulation (SCS) may have great clinical benefits, but how do these technologies impact fair sport? Authors discuss SCS for people with spinal cord injury, evidence for performance enhancement, potential health risks, and more. 🧪

link.springer.com/article/10.1...
Electroceuticals for Paralympic Athletes: A Fair Play and Classification Concern? - Sports Medicine
Electroceuticals such as brain computer interfaces and spinal cord stimulation (SCS) represent transformative strategies for neuromodulation. Research has demonstrated that SCS can ameliorate motor an...
link.springer.com
November 10, 2025 at 5:51 PM
Prior data shows plant steroids 20E and DSG improve performance, but this study found no performance-enhancing effects of a combined 20E & DSG supplement given 3x/day for 12 weeks, likely due to low concentrations of the steroids & lack of biological activity. 🧪

www.tandfonline.com/doi/10.1080/...
How reliable is the labeling of a commercial phytosteroid product? A 12-week randomized double-blind training study
Phytosteroids like 20-hydroxyecdysone (20E) and diosgenin (DSG) have shown promising anabolic and performance-enhancing effects in in vitro, animal, and human studies. Combining phytosteroids is co...
www.tandfonline.com
November 7, 2025 at 5:53 PM
hCG can ⬆️ performance by ⬆️ testosterone, & biotin can interfere with hCG lab tests. The PCC funded Dr. Miller to examine if biotin could be used as a masking agent in #antidoping tests. This work led to the discovery that biotin supplements can substantially ⬇️ urinary hCG values in immunoassays. 🧪
November 6, 2025 at 6:30 PM
Authors compared the anabolic androgenic steroid (AAS) detection abilities of 2 dried blood spot (DBS) devices to urine analysis. The DBS devices were sensitive for detecting prohibited AAS use & showed benefits vs. urine analysis. 🧪

analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
Detection of Anabolic Androgenic Steroids and Steroid Esters—Comparing Dried Blood Spots Collection Devices and Urine Samples
DBS (Capitainer-B50 and Tasso-M20) enabled detection of testosterone esters in all participants, whereas urine testing (T/E) missed cases including potential UGT2B17 del/del carriers and individuals ...
analyticalsciencejournals.onlinelibrary.wiley.com
November 5, 2025 at 4:25 PM
In episode 2 of our 2-episode feature on @biotage.bsky.social, Esraa AboJasser & Dr. Lee Williams discuss their consumable products, activities in North America, educational endeavors, future goals, preparations for the LA28 Olympic & Paralympic Games, & more. 🧪

cleancompetition.org/anti-doping-...
161 - How Biotage Supports Scientists and Advances Anti-Doping in the North America - Esraa AboJasser and Dr. Lee Williams - PCC - Global Anti-Doping Research Grants for Scientists and Researchers
0.75x 1x 1.25x 1.5x 2x 0:0031:34 161 – How Biotage Supports Scientists and Advances Anti-Doping in the North America – Esraa AboJasser and Dr. Lee Williams Apple PodcastsGoogle PodcastsPlayer EmbedSha...
cleancompetition.org
November 4, 2025 at 3:08 PM
Researchers examined the excretion of metabolites of the anabolic androgenic steroid metandienone (MD). They identified new metabolites & detected E3, a metabolite that could increase the detection window for MD in #antidoping analyses. 🧪

linkinghub.elsevier.com/retrieve/pii/S0960-0760(25)00129-3
November 3, 2025 at 4:46 PM
Limitations in ABP biomarkers make it essential to identify new complimentary biomarkers. Researchers identified hypoxanthine and inosine as 2 novel metabolite biomarkers that showed significant increases after EPO administration. 🧪

analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
Identification of Candidate Blood Biomarkers of Recombinant Human Erythropoietin Administration Using Targeted Polar Metabolomics by HILIC‐MS/MS
Using targeted HILIC-MS/MS metabolomics, inosine and hypoxanthine were identified as potential biomarkers of EPO administration. Their consistent and sensitive plasma responses highlight their promis....
analyticalsciencejournals.onlinelibrary.wiley.com
October 31, 2025 at 3:48 PM
Every lab is different, and Biotage serves a wide range of labs around the world, including many #antidoping labs. Developing solutions that work for each lab's unique situation & needs is key for enhancing and advancing #cleansport.

Learn more in this episode:
cleancompetition.org/anti-doping-...
October 30, 2025 at 5:33 PM
Authors retrospectively analyzed anabolic androgenic steroids (AAS) in non-sport samples & reanalyzed 310 samples for additional AAS. Understanding patterns of drug use helps inform #antidoping education & public health policies. 🧪

analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
October 29, 2025 at 5:15 PM
Partnerships and collaborations are critical for advancing #antidoping approaches & analyses. Dr. Lee Williams and Monika Vezse from @biotage.bsky.social discuss how they work closely with customers to develop solutions & drive innovation in anti-doping & beyond.
cleancompetition.org/anti-doping-...
October 28, 2025 at 3:16 PM
Over-the-counter topical products may contain the steroid clostebol. Authors examined the metabolism of oral vs. topical clostebol & propose using ratios between metabolites as a method to distinguish between administration routes. 🧪
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
Clostebol Metabolism by Different Routes of Administration: Selection of Diagnostic Urinary Markers
The metabolism of clostebol after oral and transdermal applications was described. Ten metabolites were detected after oral administration (M1–M10), but only five (M1–M4 and M9) could be detected aft...
analyticalsciencejournals.onlinelibrary.wiley.com
October 27, 2025 at 4:56 PM
Anti-doping analyses for steroids can be costly & time-intensive. Authors developed & validated an efficient & effective method using liquid chromatography-(low-resolution)-MS3 that detected 17 steroidal esters from dried blood spots.
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
October 24, 2025 at 6:26 PM
Through his 2021 PCC Research Grant, Prof. Nikos Ntoumanis conducted a review and meta-analysis of 200+ studies of psychosocial predictors and correlates of doping intention, use, and inadvertent doping in sport and exercise. 🚫💊 🧪

The results were published last year: bjsm.bmj.com/content/bjsp...
October 23, 2025 at 5:41 PM
Can serum testosterone-to-luteinizing hormone ratio, measured w/ an automated immunoassay platform, benefit routine #antidoping analysis to detect testosterone abuse? Results showed serum ratio was sensitive & may improve detection.

analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
Evaluating the Testosterone‐to‐Luteinizing Hormone Ratio in Male Anti‐Doping Serum Samples: Results From a Transdermal Testosterone Administration Trial and Field Collected Samples
Practicality of serum T/LH ratio was investigated in the context of a transdermal testosterone administration study and a field study where the T/LH ratio was measured using an automated immunoassay ...
analyticalsciencejournals.onlinelibrary.wiley.com
October 22, 2025 at 3:50 PM
In the 1st episode of our 2-episode feature on Biotage, Monika Vezse & Dr. Lee Williams share the company's history, discuss some of their products used by #antidoping labs & researchers, & describe their work to support anti-doping efforts in the EMEA region. 🧪

cleancompetition.org/anti-doping-...
160 - Biotage's Role In Protecting Clean Sport in the EMEA Region - Monika Vezse and Dr. Lee Williams - PCC - Global Anti-Doping Research Grants for Scientists and Researchers
0.75x 1x 1.25x 1.5x 2x 0:0033:07 160 – Biotage’s Role In Protecting Clean Sport in the EMEA Region – Monika Vezse and Dr. Lee Williams Apple PodcastsGoogle PodcastsPlayer EmbedShare Leave a ReviewList...
cleancompetition.org
October 21, 2025 at 2:31 PM
Authors identified 4 motivational profiles with differences in doping risk & protective factors. The profiles & relative risk across profiles were consistent in 2 samples. Identifying at‐risk profiles may inform new screening tools & targeted interventions.

onlinelibrary.wiley.com/doi/10.1111/...
Latent Motivation Profiles and Doping in Sport and Exercise: An Integrative Approach Based on Achievement Goal and Self‐Determination Theories
Utilizing adult sport (Study 1: N = 290; Mage = 25.0 years, SD = 10.9) and exercise (Study 2: N = 501; Mage = 23.9 years, SD = 7.2) samples—competing and training at a range of levels—we identified s...
onlinelibrary.wiley.com
October 20, 2025 at 3:21 PM
#Antidoping efforts in gyms & fitness centers may deter performance & image-enhancing drug use & protect public health. Authors found 35% of countries in this study had anti-doping measures in gyms & fitness centers, & NADOs were key for implementing them. 🚫💊 🧪

www.sciencedirect.com/science/arti...
October 17, 2025 at 4:51 PM
Human growth hormone (hGH) abuse is hard to detect directly, and the PCC was proud to fund research, led by Dr. Andy Hoofnagle, on the use of biomarkers of collagen turnover to indirectly detect doping with hGH. This work led to the development of novel assays to monitor collagen turnover.
🚫💊 🧪
October 16, 2025 at 4:05 PM
Detecting testosterone (T) doping is a challenge in #antidoping, even with advances in the Athlete Biological Passport. Researchers investigated the effects of oral and transdermal T administration on various biomarkers and phase II metabolites in males. 🧪

www.sciencedirect.com/science/arti...
Evaluation of endogenous steroid sulfates and glucuronides in urine after oral and transdermal administration of testosterone. Part I: Male participants
The detection of the performance-enhancing drug testosterone (T) remains a significant challenge in doping control analysis. Longitudinal monitoring t…
www.sciencedirect.com
October 15, 2025 at 3:29 PM
Olympian Shannon Rowbury had to wait 13 years to be recognized as a London 2012 Games bronze medalist because of doping competitors. She shared her hard-fought journey as an athlete, how doping has impacted her and her sport, and what's next on the horizon. 🚫💊

cleancompetition.org/anti-doping-...
October 14, 2025 at 4:35 PM
Through a controlled administration study, researchers found that 2 weeks of daily clenbuterol induced lean mass gain and muscle protein accretion, but it had clear negative effects on cardiorespiratory fitness & muscle oxidative capacity.

pmc.ncbi.nlm.nih.gov/articles/PMC...

#antidoping #science
October 10, 2025 at 3:46 PM
Peptide doping agents can be hard to detect, especially if they are in low abundance in biological matrices. The PCC was excited to support a research project led by Dr. Trine Grønhaug Halvorsen which focused on developing & testing a novel smart sampler using affinity capture to address this issue.
October 9, 2025 at 6:05 PM
What leads athletes to dope? New research sheds light on the psychosocial mechanisms of doping, and researchers' findings across 3 countries consistently showed vulnerable narcissism is a critical correlate of doping.

harmreductionjournal.biomedcentral.com/articles/10....

#antidoping #science
The ‘selves’ in doping and its psychosocial mechanisms: harmonised multi-country evidence from high-performing athletes in the UK, US, and China - Harm Reduction Journal
Background Doping remains an ongoing threat to clean competition. To date, global preventive initiatives have not addressed critical psychosocial antecedents of doping thoroughly due to the scarcity of knowledge regarding its psychosocial mechanisms from a harmonised cross-country perspective. We, therefore, conducted a multi-country investigation testing the interplay of two important yet overlooked attributes, namely narcissism and self-compassion, and examined their psychosocial mechanisms underpinning doping. Methods Using a sample of 499 high-performing athletes (80% competing at national level or above) from the UK, US, and China, we performed a series of multi-variate multi-group moderation models to test the narcissism × compassion interaction on doping and examined potential psychosocial mechanisms underlying such effects. In all analyses, we applied cluster control to adjust for coach-/team-level confounds and compared fixed vs. random effects models for cross-country comparisons. Results We found an identical interaction across study countries showing self-compassion alleviates narcissism-related doping willingness (especially that vulnerable narcissism drives). Grandiose narcissism’s protective effect on vulnerable narcissism-related doping moral disengagement was invariant across countries. Resilient coping appears to be a consistent mechanism across study countries that explains narcissism-related risk and compassion-related protection. Fear of failure manifested varied mechanistic effects in different study countries, inferring potential cross-cultural differences. Conclusion Vulnerable narcissism is a critical person-level correlate of doping. Grandiose narcissism, in the presence of self-compassion, can alleviate such risk thanks to enhanced resilient coping. Future education and interventions should tackle these important person-level attributes for anti-doping.
harmreductionjournal.biomedcentral.com
October 8, 2025 at 5:14 PM
New episode! The detrimental impacts of doping extend far beyond a missed medal ceremony for clean athletes. Olympic bronze medalist Shannon Rowbury shared her remarkable athletic career, her commitment to #cleansport, and her story from the London 2012 Games. 🚫💊
cleancompetition.org/anti-doping-...
159 - The 13-Year Battle for Olympic Bronze and the Impacts of Doping on Clean Athletes - Shannon Rowbury - PCC - Global Anti-Doping Research Grants for Scientists and Researchers
0.75x 1x 1.25x 1.5x 2x 0:0053:38 159 – The 13-Year Battle for Olympic Bronze and the Impacts of Doping on Clean Athletes – Shannon Rowbury Apple PodcastsGoogle PodcastsPlayer EmbedShare Leave a Review...
cleancompetition.org
October 7, 2025 at 3:06 PM