Pablo Santos (dos Santos)
@osteocyte.bsky.social
Master's student, Brazilian, aspiring to become a great scientist.
Reposted by Pablo Santos (dos Santos)
Read the latest Special Topic on Endothelial Cell and Pericyte Homeostasis and Pathogenesis in JHC: "Role of the Pancreatic Islet Microvasculature in Health and Disease."
Click to read for FREE: bit.ly/4fihNMw
#capillary #diabetes #endothelialcell
Click to read for FREE: bit.ly/4fihNMw
#capillary #diabetes #endothelialcell
January 27, 2025 at 9:06 PM
Read the latest Special Topic on Endothelial Cell and Pericyte Homeostasis and Pathogenesis in JHC: "Role of the Pancreatic Islet Microvasculature in Health and Disease."
Click to read for FREE: bit.ly/4fihNMw
#capillary #diabetes #endothelialcell
Click to read for FREE: bit.ly/4fihNMw
#capillary #diabetes #endothelialcell
Reposted by Pablo Santos (dos Santos)
"Intestinal Tuft Cells Are Enriched With Protocadherins."
Click to read: bit.ly/4hlyARd
#epithelium #gut #immunostaining
Click to read: bit.ly/4hlyARd
#epithelium #gut #immunostaining
February 7, 2025 at 11:14 PM
"Intestinal Tuft Cells Are Enriched With Protocadherins."
Click to read: bit.ly/4hlyARd
#epithelium #gut #immunostaining
Click to read: bit.ly/4hlyARd
#epithelium #gut #immunostaining
Reposted by Pablo Santos (dos Santos)
Human coronavirus OC43 infection remodels Connexin 43 mediated gap junction intercellular communication in vitro https://www.biorxiv.org/content/10.1101/2023.11.20.567927v1
Human coronavirus OC43 infection remodels Connexin 43 mediated gap junction intercellular communication in vitro https://www.biorxiv.org/content/10.1101/2023.11.20.567927v1
{beta}-coronaviruses cause acute infection in the upper respiratory tract, resulting in various symp
www.biorxiv.org
November 22, 2023 at 3:03 AM
Human coronavirus OC43 infection remodels Connexin 43 mediated gap junction intercellular communication in vitro https://www.biorxiv.org/content/10.1101/2023.11.20.567927v1
Reposted by Pablo Santos (dos Santos)
Structural basis of connexin-36 gap junction channel inhibition https://www.biorxiv.org/content/10.1101/2023.12.09.570920v1
Structural basis of connexin-36 gap junction channel inhibition https://www.biorxiv.org/content/10.1101/2023.12.09.570920v1
Connexin gap junction channels and hemichannels play important roles in intercellular communication
www.biorxiv.org
December 9, 2023 at 11:52 PM
Structural basis of connexin-36 gap junction channel inhibition https://www.biorxiv.org/content/10.1101/2023.12.09.570920v1
Reposted by Pablo Santos (dos Santos)
Orally Delivered Milk-Derived Nanovesicles Loaded with Connexin 43 Peptides forTargeted Cardiac Ischemia-Reperfusion Therapy https://www.biorxiv.org/content/10.1101/2025.01.01.630994v1
January 2, 2025 at 6:46 PM
Orally Delivered Milk-Derived Nanovesicles Loaded with Connexin 43 Peptides forTargeted Cardiac Ischemia-Reperfusion Therapy https://www.biorxiv.org/content/10.1101/2025.01.01.630994v1
Reposted by Pablo Santos (dos Santos)
17β-Estradiol Counteracts Pathological Microtubule Remodeling To Enhance Cardiac Function https://www.biorxiv.org/content/10.1101/2025.01.22.634271v1
January 25, 2025 at 4:04 AM
17β-Estradiol Counteracts Pathological Microtubule Remodeling To Enhance Cardiac Function https://www.biorxiv.org/content/10.1101/2025.01.22.634271v1
Reposted by Pablo Santos (dos Santos)
TGR5-mediated Ca2+ signaling in cholangiocytes https://www.biorxiv.org/content/10.1101/2025.01.23.634480v1
January 26, 2025 at 8:02 PM
TGR5-mediated Ca2+ signaling in cholangiocytes https://www.biorxiv.org/content/10.1101/2025.01.23.634480v1
Reposted by Pablo Santos (dos Santos)
Targeting Runx1 protects against heart failure with preserved ejection fraction https://www.biorxiv.org/content/10.1101/2025.01.24.634831v1
January 27, 2025 at 2:03 PM
Targeting Runx1 protects against heart failure with preserved ejection fraction https://www.biorxiv.org/content/10.1101/2025.01.24.634831v1
Reposted by Pablo Santos (dos Santos)
Perilysosomal Ca2+ overload impairs autophagic degradation in β-cell lipotoxicity https://www.biorxiv.org/content/10.1101/2025.01.27.635047v1
January 29, 2025 at 9:02 PM
Perilysosomal Ca2+ overload impairs autophagic degradation in β-cell lipotoxicity https://www.biorxiv.org/content/10.1101/2025.01.27.635047v1
Reposted by Pablo Santos (dos Santos)
🧪 #Bone meets the scanning electron microscope 🦴🔬
Detailed description in Alt text
#MicroscopyMonday #science #biology #biomineralization #biomaterials #imaging #bioimaging #electronmicroscopy #mineral #collagen #apatite
www.nature.com/articles/s41...
Detailed description in Alt text
#MicroscopyMonday #science #biology #biomineralization #biomaterials #imaging #bioimaging #electronmicroscopy #mineral #collagen #apatite
www.nature.com/articles/s41...
December 2, 2024 at 10:07 AM
🧪 #Bone meets the scanning electron microscope 🦴🔬
Detailed description in Alt text
#MicroscopyMonday #science #biology #biomineralization #biomaterials #imaging #bioimaging #electronmicroscopy #mineral #collagen #apatite
www.nature.com/articles/s41...
Detailed description in Alt text
#MicroscopyMonday #science #biology #biomineralization #biomaterials #imaging #bioimaging #electronmicroscopy #mineral #collagen #apatite
www.nature.com/articles/s41...
Reposted by Pablo Santos (dos Santos)
Moesin activation controls bone resorption and tunneling nanotube-dependent osteoclast fusion https://www.biorxiv.org/content/10.1101/2024.05.13.593799v1
Moesin activation controls bone resorption and tunneling nanotube-dependent osteoclast fusion https://www.biorxiv.org/content/10.1101/2024.05.13.593799v1
Osteoclasts are multinucleated cells unique in their ability to resorb bone. Osteoclastogenesis invo
www.biorxiv.org
May 15, 2024 at 8:31 PM
Moesin activation controls bone resorption and tunneling nanotube-dependent osteoclast fusion https://www.biorxiv.org/content/10.1101/2024.05.13.593799v1
Reposted by Pablo Santos (dos Santos)
Did you know it’s Osteoclast Appreciation Day, today? It’s not really, I’m just kidding. But they’re my favourite cells, & don’t you think they deserve their own special day?
December 1, 2024 at 6:18 AM
Did you know it’s Osteoclast Appreciation Day, today? It’s not really, I’m just kidding. But they’re my favourite cells, & don’t you think they deserve their own special day?
Reposted by Pablo Santos (dos Santos)
Mechanosensing by Piezo1 regulates osteoclast differentiation via PP2A-Akt axis in periodontitis https://www.biorxiv.org/content/10.1101/2024.09.04.611049v1
Mechanosensing by Piezo1 regulates osteoclast differentiation via PP2A-Akt axis in periodontitis https://www.biorxiv.org/content/10.1101/2024.09.04.611049v1
Mechanical stimulus to the multicellular bone unit (MBU) plays a key role in normal bone remodeling,
www.biorxiv.org
September 5, 2024 at 2:31 PM
Mechanosensing by Piezo1 regulates osteoclast differentiation via PP2A-Akt axis in periodontitis https://www.biorxiv.org/content/10.1101/2024.09.04.611049v1
Reposted by Pablo Santos (dos Santos)
Pages 23-31 of 'Osteon/Osteoclast,'fast(ish) works made to help ease the mind, or allow the subconscious to breathe
Older camera, older images. I am shy of sharing them, as it seems an atypical artwork related to Gaster
But, for now, it seems the time to be shy is over. Better simply to be as I am
Older camera, older images. I am shy of sharing them, as it seems an atypical artwork related to Gaster
But, for now, it seems the time to be shy is over. Better simply to be as I am
November 6, 2024 at 2:44 PM
Pages 23-31 of 'Osteon/Osteoclast,'fast(ish) works made to help ease the mind, or allow the subconscious to breathe
Older camera, older images. I am shy of sharing them, as it seems an atypical artwork related to Gaster
But, for now, it seems the time to be shy is over. Better simply to be as I am
Older camera, older images. I am shy of sharing them, as it seems an atypical artwork related to Gaster
But, for now, it seems the time to be shy is over. Better simply to be as I am
Reposted by Pablo Santos (dos Santos)
Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast https://www.biorxiv.org/content/10.1101/2024.02.20.581167v1
Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast https://www.biorxiv.org/content/10.1101/2024.02.20.581167v1
It has been well-validated that chronic psychological stress leads to bone loss, but the underlying
www.biorxiv.org
February 23, 2024 at 7:17 PM
Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast https://www.biorxiv.org/content/10.1101/2024.02.20.581167v1
Reposted by Pablo Santos (dos Santos)
I really must start posting here - work and personal life have been crazy.
In the mean time enjoy this osteoclast - a bit like Bluesky joining together in clearance renewal.
In the mean time enjoy this osteoclast - a bit like Bluesky joining together in clearance renewal.
November 24, 2024 at 4:05 PM
I really must start posting here - work and personal life have been crazy.
In the mean time enjoy this osteoclast - a bit like Bluesky joining together in clearance renewal.
In the mean time enjoy this osteoclast - a bit like Bluesky joining together in clearance renewal.
Reposted by Pablo Santos (dos Santos)
December 27, 2024 at 2:26 AM
Reposted by Pablo Santos (dos Santos)
American Museum of Natural History
January 21, 2024 at 5:08 PM
American Museum of Natural History
Reposted by Pablo Santos (dos Santos)
🦴🔬#Osteocyte – the master orchestrator of #bone #remodeling. ~42 billion in the average adult human skeleton, #osteocytes make up ~90–95% of all #cells within bone, interconnected by ~3.7 trillion dendritic projections with an estimated, total end-to-end length of 175,000 km 🔍
December 28, 2023 at 11:55 PM
🦴🔬#Osteocyte – the master orchestrator of #bone #remodeling. ~42 billion in the average adult human skeleton, #osteocytes make up ~90–95% of all #cells within bone, interconnected by ~3.7 trillion dendritic projections with an estimated, total end-to-end length of 175,000 km 🔍
Porra cara, eu amo muito a minha namorada
September 3, 2024 at 9:43 PM
Porra cara, eu amo muito a minha namorada