Rob Beynon
@originalastacus.bsky.social
Retired biochemist. Technologically overstimulated ex-scientist. 🏴 Proudly a FLSW, currently VP STEMM 🏴
Keen 📷 of mostly 🦜. See Bird pics: http://rjbwild.smugmug.com
Inventor of Zwitter!
Web site: http://www.phbuffers.org
Keen 📷 of mostly 🦜. See Bird pics: http://rjbwild.smugmug.com
Inventor of Zwitter!
Web site: http://www.phbuffers.org
One for the scientists
My site for calculation of recipes for thermodynamically correct pH buffers has data about the buffers that are made.
phbuffers.org/BuffferCalc/...
Analysis of about 40,000 buffers. -> lot of the five most common buffer species. Anyone care to guess what these top 5 are?
My site for calculation of recipes for thermodynamically correct pH buffers has data about the buffers that are made.
phbuffers.org/BuffferCalc/...
Analysis of about 40,000 buffers. -> lot of the five most common buffer species. Anyone care to guess what these top 5 are?
August 15, 2025 at 8:49 PM
One for the scientists
My site for calculation of recipes for thermodynamically correct pH buffers has data about the buffers that are made.
phbuffers.org/BuffferCalc/...
Analysis of about 40,000 buffers. -> lot of the five most common buffer species. Anyone care to guess what these top 5 are?
My site for calculation of recipes for thermodynamically correct pH buffers has data about the buffers that are made.
phbuffers.org/BuffferCalc/...
Analysis of about 40,000 buffers. -> lot of the five most common buffer species. Anyone care to guess what these top 5 are?
Many of you (say, about one million) have used my buffer site to calculate thermodynamically correct buffers. Well, today, I upgraded the site with added security, becuase it was stopping soem people connecting. Should all be fine now. https rather than http. Enjoy!
phbuffers.org/BuffferCalc/...
phbuffers.org/BuffferCalc/...
July 11, 2025 at 6:38 PM
Many of you (say, about one million) have used my buffer site to calculate thermodynamically correct buffers. Well, today, I upgraded the site with added security, becuase it was stopping soem people connecting. Should all be fine now. https rather than http. Enjoy!
phbuffers.org/BuffferCalc/...
phbuffers.org/BuffferCalc/...
Just before the Beynfest! Claude continues to impress. I asked it to write a simple protein dotplot tool to explain to a PhD student how two sequences are related, and 20 minutes later:
phbuffers.org/Claude/DotPl...
Free for all to use...
phbuffers.org/Claude/DotPl...
Free for all to use...
July 7, 2025 at 12:19 PM
Just before the Beynfest! Claude continues to impress. I asked it to write a simple protein dotplot tool to explain to a PhD student how two sequences are related, and 20 minutes later:
phbuffers.org/Claude/DotPl...
Free for all to use...
phbuffers.org/Claude/DotPl...
Free for all to use...
Slight ambarassed to be at the ’Putting Beynon out to pasture’ celebration at @ukbspr.bsky.social tomorrow. Thanks to the organisers…
July 6, 2025 at 9:31 PM
Slight ambarassed to be at the ’Putting Beynon out to pasture’ celebration at @ukbspr.bsky.social tomorrow. Thanks to the organisers…
Here's the annotation language for peptidemapper
phbuffers.org/Claude/pepti...
phbuffers.org/Claude/pepti...
PeptideMapper Annotation Syntax Guide
phbuffers.org
June 25, 2025 at 9:36 PM
Here's the annotation language for peptidemapper
phbuffers.org/Claude/pepti...
phbuffers.org/Claude/pepti...
"I Claudiused" - tragic tale.
My tool is now silly. (haven't quite made a mess-alina of it though!). Has a flexible annotation language, which was not easy to get right. But "P14 sequence blue out above L1" means "Label P14 with its sequence in blue outside the map" @catfranco.bsky.social
My tool is now silly. (haven't quite made a mess-alina of it though!). Has a flexible annotation language, which was not easy to get right. But "P14 sequence blue out above L1" means "Label P14 with its sequence in blue outside the map" @catfranco.bsky.social
June 25, 2025 at 9:27 PM
"I Claudiused" - tragic tale.
My tool is now silly. (haven't quite made a mess-alina of it though!). Has a flexible annotation language, which was not easy to get right. But "P14 sequence blue out above L1" means "Label P14 with its sequence in blue outside the map" @catfranco.bsky.social
My tool is now silly. (haven't quite made a mess-alina of it though!). Has a flexible annotation language, which was not easy to get right. But "P14 sequence blue out above L1" means "Label P14 with its sequence in blue outside the map" @catfranco.bsky.social
Oh yes, the URL of the peptide mapper:
phbuffers.org/Claude/pepti...
phbuffers.org/Claude/pepti...
PeptideMapper by Rob Beynon
phbuffers.org
June 24, 2025 at 4:52 PM
Oh yes, the URL of the peptide mapper:
phbuffers.org/Claude/pepti...
phbuffers.org/Claude/pepti...
So, I rewrote my little peptide mapping tool
And, in conversation with @catfranco.bsky.social she suggested a feature - so, in 5 minutes, it was implemented.with an annotation language
K fill cyan
C circle yellow in
V diamond green out below
P45 fill orange
Fun!
And, in conversation with @catfranco.bsky.social she suggested a feature - so, in 5 minutes, it was implemented.with an annotation language
K fill cyan
C circle yellow in
V diamond green out below
P45 fill orange
Fun!
June 24, 2025 at 9:13 AM
So, I rewrote my little peptide mapping tool
And, in conversation with @catfranco.bsky.social she suggested a feature - so, in 5 minutes, it was implemented.with an annotation language
K fill cyan
C circle yellow in
V diamond green out below
P45 fill orange
Fun!
And, in conversation with @catfranco.bsky.social she suggested a feature - so, in 5 minutes, it was implemented.with an annotation language
K fill cyan
C circle yellow in
V diamond green out below
P45 fill orange
Fun!
OK, I have been playing with AI for coding (Claude) and I am stunned. This was to develop a web app for decoding a highly compressed/efficient data logger, binary file and unpack into human useable form. I gave Claude the original binary file and the decoded output. 1/
June 19, 2025 at 8:49 AM
OK, I have been playing with AI for coding (Claude) and I am stunned. This was to develop a web app for decoding a highly compressed/efficient data logger, binary file and unpack into human useable form. I gave Claude the original binary file and the decoded output. 1/
Sad to hear of death of Bill Atkinson, inventor of Hypercard.. the first home for my buffer calculator ..now at phbuffers.org ( no fee, no adds, no cookies) @benneely.com
Professor Rob Beynon
phbuffers.org
June 8, 2025 at 9:39 PM
Sad to hear of death of Bill Atkinson, inventor of Hypercard.. the first home for my buffer calculator ..now at phbuffers.org ( no fee, no adds, no cookies) @benneely.com
Pleased to see this very nice paper out by an excellent team. Mass spec where you do not know what you are measuring - this is the sort of area where AI can make a difference.. to be seen. All data sets are public, so lots of opportunity. Open access, of course.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Rapid evaporative ionisation mass spectrometry can age field caught Anopheles gambiae malaria vectors - Scientific Reports
Scientific Reports - Rapid evaporative ionisation mass spectrometry can age field caught Anopheles gambiae malaria vectors
www.nature.com
June 3, 2025 at 7:17 AM
Pleased to see this very nice paper out by an excellent team. Mass spec where you do not know what you are measuring - this is the sort of area where AI can make a difference.. to be seen. All data sets are public, so lots of opportunity. Open access, of course.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Topic for discussion (1978) : @magnuspalmblad.bsky.social @benneely.com
May 17, 2025 at 6:07 AM
Topic for discussion (1978) : @magnuspalmblad.bsky.social @benneely.com
Reposted by Rob Beynon
Sky News CONTINUING to refer to the chancellor as ‘Rachel from
Accounts’, would they have referred to a male chancellor by an insulting nickname? Of course not.
It’s misogynistic and they’re repeating it.
Accounts’, would they have referred to a male chancellor by an insulting nickname? Of course not.
It’s misogynistic and they’re repeating it.
January 29, 2025 at 10:29 AM
Sky News CONTINUING to refer to the chancellor as ‘Rachel from
Accounts’, would they have referred to a male chancellor by an insulting nickname? Of course not.
It’s misogynistic and they’re repeating it.
Accounts’, would they have referred to a male chancellor by an insulting nickname? Of course not.
It’s misogynistic and they’re repeating it.
I let an AI write about Zwitter (phbuffers.org). I'm actually quite impressed with what it produced after a bit of coaching.
January 30, 2025 at 12:12 PM
I let an AI write about Zwitter (phbuffers.org). I'm actually quite impressed with what it produced after a bit of coaching.
Dear Research Fish, I'm retired for five years, and am not pushing out streams of outputs anymore, apart from bird photographs and vegetables. Since these are not reportable, please let me off the hook. In any case, I am not going to take part this year, except at my usual consultancy rates.😀
January 30, 2025 at 9:43 AM
Dear Research Fish, I'm retired for five years, and am not pushing out streams of outputs anymore, apart from bird photographs and vegetables. Since these are not reportable, please let me off the hook. In any case, I am not going to take part this year, except at my usual consultancy rates.😀
I broke DeepSeek-
January 30, 2025 at 7:32 AM
I broke DeepSeek-
Today's bird (sorry if you see these on FB). A black winged stilt, configured for landing. Just a nice atmospheric shot.
December 12, 2024 at 7:45 PM
Today's bird (sorry if you see these on FB). A black winged stilt, configured for landing. Just a nice atmospheric shot.
Today's stunning Malagasay bird. The pygmy kingfisher. Enjoy.
December 11, 2024 at 9:23 AM
Today's stunning Malagasay bird. The pygmy kingfisher. Enjoy.
Debut port - a mouse lemur!
December 10, 2024 at 8:15 PM
Debut port - a mouse lemur!