Organic Syntheses
@orgsynth.bsky.social
Since 1921, Organic Syntheses has provided the chemistry community with detailed, reliable, & carefully checked procedures for syntheses of organic compounds.
Professor Emeritus Tohru Fukuyama (University of Tokyo) presented the Organic Syntheses Lecture at Tohoku University on November 6th, 2025.
November 5, 2025 at 3:19 PM
Professor Emeritus Tohru Fukuyama (University of Tokyo) presented the Organic Syntheses Lecture at Tohoku University on November 6th, 2025.
Discussion Addendum for: Nickel-Catalyzed Synthesis of Ketones from Alkyl Halides and Acid Chlorides: Preparation of Ethyl 4-Oxododecanoate
Omar M. Beleh and Daniel J. Weix
www.orgsyn.org/demo.aspx?pr...
Omar M. Beleh and Daniel J. Weix
www.orgsyn.org/demo.aspx?pr...
November 3, 2025 at 3:15 PM
Discussion Addendum for: Nickel-Catalyzed Synthesis of Ketones from Alkyl Halides and Acid Chlorides: Preparation of Ethyl 4-Oxododecanoate
Omar M. Beleh and Daniel J. Weix
www.orgsyn.org/demo.aspx?pr...
Omar M. Beleh and Daniel J. Weix
www.orgsyn.org/demo.aspx?pr...
Large-Scale Amino-Hydroxylation Using Tethered Nitreniums
Shyam Sathyamoorthi (medchem.ku.edu/research/shy...)
www.orgsyn.org/demo.aspx?pr...
Shyam Sathyamoorthi (medchem.ku.edu/research/shy...)
www.orgsyn.org/demo.aspx?pr...
October 31, 2025 at 1:38 PM
Large-Scale Amino-Hydroxylation Using Tethered Nitreniums
Shyam Sathyamoorthi (medchem.ku.edu/research/shy...)
www.orgsyn.org/demo.aspx?pr...
Shyam Sathyamoorthi (medchem.ku.edu/research/shy...)
www.orgsyn.org/demo.aspx?pr...
Preparation of N-tert-Butylbenzenesulfinimidoyl Chloride
Teruaki Mukaiyama, Yasuo Nakamura, and Jun-ichi Matsuo (yakugaku.w3.kanazawa-u.ac.jp/~gousei/)
www.orgsyn.org/demo.aspx?pr...
Teruaki Mukaiyama, Yasuo Nakamura, and Jun-ichi Matsuo (yakugaku.w3.kanazawa-u.ac.jp/~gousei/)
www.orgsyn.org/demo.aspx?pr...
October 29, 2025 at 12:51 PM
Preparation of N-tert-Butylbenzenesulfinimidoyl Chloride
Teruaki Mukaiyama, Yasuo Nakamura, and Jun-ichi Matsuo (yakugaku.w3.kanazawa-u.ac.jp/~gousei/)
www.orgsyn.org/demo.aspx?pr...
Teruaki Mukaiyama, Yasuo Nakamura, and Jun-ichi Matsuo (yakugaku.w3.kanazawa-u.ac.jp/~gousei/)
www.orgsyn.org/demo.aspx?pr...
Oxidative Nitrogen Atom Insertion into Cyclopentenones
Bence B. Botlik and Bill Morandi (morandi.ethz.ch)
www.orgsyn.org/demo.aspx?pr...
Bence B. Botlik and Bill Morandi (morandi.ethz.ch)
www.orgsyn.org/demo.aspx?pr...
October 8, 2025 at 1:28 PM
Oxidative Nitrogen Atom Insertion into Cyclopentenones
Bence B. Botlik and Bill Morandi (morandi.ethz.ch)
www.orgsyn.org/demo.aspx?pr...
Bence B. Botlik and Bill Morandi (morandi.ethz.ch)
www.orgsyn.org/demo.aspx?pr...
Summer 2026-2027 Research Grants for Faculty at Principally Undergraduate Institutions:
Applications are due by November 1, 2025. For more information, visit orgsyn.org/puigrants.aspx
Applications are due by November 1, 2025. For more information, visit orgsyn.org/puigrants.aspx
October 7, 2025 at 3:28 PM
Summer 2026-2027 Research Grants for Faculty at Principally Undergraduate Institutions:
Applications are due by November 1, 2025. For more information, visit orgsyn.org/puigrants.aspx
Applications are due by November 1, 2025. For more information, visit orgsyn.org/puigrants.aspx
Professor Jeff Gustafson (Stony Brook University) (gustafsongroup.sdsu.edu/wordpress/) presented the Organic Syntheses Lecture at Notre Dame on September 24th, 2025.
September 24, 2025 at 6:56 PM
Professor Jeff Gustafson (Stony Brook University) (gustafsongroup.sdsu.edu/wordpress/) presented the Organic Syntheses Lecture at Notre Dame on September 24th, 2025.
Professor Vy Dong (UC Irvine) (sites.google.com/uci.edu/vydo...) and Dr. Jeff Kallemeyn (abbVie) presented the Organic Syntheses Lectures at Iowa State on September 12th 2025.
September 17, 2025 at 11:34 AM
Professor Vy Dong (UC Irvine) (sites.google.com/uci.edu/vydo...) and Dr. Jeff Kallemeyn (abbVie) presented the Organic Syntheses Lectures at Iowa State on September 12th 2025.
Synthesis of Abietatriene via Nitrogen Deletion
Julia L. Driscoll, Carys E. Obertone, Liao Chen, and Mark D. Levin (levingroup.uchicago.edu)
www.orgsyn.org/demo.aspx?pr...
Julia L. Driscoll, Carys E. Obertone, Liao Chen, and Mark D. Levin (levingroup.uchicago.edu)
www.orgsyn.org/demo.aspx?pr...
September 15, 2025 at 5:59 PM
Synthesis of Abietatriene via Nitrogen Deletion
Julia L. Driscoll, Carys E. Obertone, Liao Chen, and Mark D. Levin (levingroup.uchicago.edu)
www.orgsyn.org/demo.aspx?pr...
Julia L. Driscoll, Carys E. Obertone, Liao Chen, and Mark D. Levin (levingroup.uchicago.edu)
www.orgsyn.org/demo.aspx?pr...
Hydrosilylation of Propiolate Esters
Allison M. Clark, Giulianna Miseo, and Neil K. Garg (garg.chem.ucla.edu)
www.orgsyn.org/demo.aspx?pr...
Allison M. Clark, Giulianna Miseo, and Neil K. Garg (garg.chem.ucla.edu)
www.orgsyn.org/demo.aspx?pr...
September 15, 2025 at 5:56 PM
Hydrosilylation of Propiolate Esters
Allison M. Clark, Giulianna Miseo, and Neil K. Garg (garg.chem.ucla.edu)
www.orgsyn.org/demo.aspx?pr...
Allison M. Clark, Giulianna Miseo, and Neil K. Garg (garg.chem.ucla.edu)
www.orgsyn.org/demo.aspx?pr...
Acid-Mediated Hydroaminomethylation of Unactivated Alkenes
Uros Vezonik, Paolo Piacentini and Nuno Maulide (maulide.univie.ac.at)
www.orgsyn.org/demo.aspx?pr...
Uros Vezonik, Paolo Piacentini and Nuno Maulide (maulide.univie.ac.at)
www.orgsyn.org/demo.aspx?pr...
September 15, 2025 at 5:52 PM
Acid-Mediated Hydroaminomethylation of Unactivated Alkenes
Uros Vezonik, Paolo Piacentini and Nuno Maulide (maulide.univie.ac.at)
www.orgsyn.org/demo.aspx?pr...
Uros Vezonik, Paolo Piacentini and Nuno Maulide (maulide.univie.ac.at)
www.orgsyn.org/demo.aspx?pr...
Large-Scale Alkene Dimesyloxylation
Shyam Sathyamoorthi (medchem.ku.edu/research/shy...)
www.orgsyn.org/demo.aspx?pr...
Shyam Sathyamoorthi (medchem.ku.edu/research/shy...)
www.orgsyn.org/demo.aspx?pr...
September 9, 2025 at 6:03 PM
Large-Scale Alkene Dimesyloxylation
Shyam Sathyamoorthi (medchem.ku.edu/research/shy...)
www.orgsyn.org/demo.aspx?pr...
Shyam Sathyamoorthi (medchem.ku.edu/research/shy...)
www.orgsyn.org/demo.aspx?pr...
Top Ten Organic Syntheses Articles (Volume 65 to present) accessed during 2024
(8) Jacobsen Mn Salen Epoxidation Catalyst Prepn. OS 1998, 75, 1
(9) Campagne Dipeptide Synthesis OS 2015, 92, 296
(10) Alberico Oxyma Peptide Synthesis OS 2013, 90, 306
(8) Jacobsen Mn Salen Epoxidation Catalyst Prepn. OS 1998, 75, 1
(9) Campagne Dipeptide Synthesis OS 2015, 92, 296
(10) Alberico Oxyma Peptide Synthesis OS 2013, 90, 306
August 28, 2025 at 12:03 PM
Top Ten Organic Syntheses Articles (Volume 65 to present) accessed during 2024
(8) Jacobsen Mn Salen Epoxidation Catalyst Prepn. OS 1998, 75, 1
(9) Campagne Dipeptide Synthesis OS 2015, 92, 296
(10) Alberico Oxyma Peptide Synthesis OS 2013, 90, 306
(8) Jacobsen Mn Salen Epoxidation Catalyst Prepn. OS 1998, 75, 1
(9) Campagne Dipeptide Synthesis OS 2015, 92, 296
(10) Alberico Oxyma Peptide Synthesis OS 2013, 90, 306
Top Ten Organic Syntheses Articles (Volume 65 to present) accessed during 2024
(5) Tschaen NaOCl-TEMPO Oxidation OS 2005, 81, 195
(6) Ellman (S)-Nonafluorobutanesulfinamide Preparation OS 2005, 93, 319
(7) Danheiser Ynamide Synthesis OS 2007, 84, 88
(5) Tschaen NaOCl-TEMPO Oxidation OS 2005, 81, 195
(6) Ellman (S)-Nonafluorobutanesulfinamide Preparation OS 2005, 93, 319
(7) Danheiser Ynamide Synthesis OS 2007, 84, 88
August 28, 2025 at 12:02 PM
Top Ten Organic Syntheses Articles (Volume 65 to present) accessed during 2024
(5) Tschaen NaOCl-TEMPO Oxidation OS 2005, 81, 195
(6) Ellman (S)-Nonafluorobutanesulfinamide Preparation OS 2005, 93, 319
(7) Danheiser Ynamide Synthesis OS 2007, 84, 88
(5) Tschaen NaOCl-TEMPO Oxidation OS 2005, 81, 195
(6) Ellman (S)-Nonafluorobutanesulfinamide Preparation OS 2005, 93, 319
(7) Danheiser Ynamide Synthesis OS 2007, 84, 88
Top Ten Organic Syntheses Articles (Volume 65 to present) accessed during 2024
(1) Kelly Carbazole Photoredox Catalyst OS 2019, 96, 455
(2) Taber Oxone Preparation OS 2013, 90, 350
(3) Miyaura Bis(pinacolato)diboron OS 2000, 77, 176
(4) Boeckman Dess Martin Reagent OS 2000, 77, 141
(1) Kelly Carbazole Photoredox Catalyst OS 2019, 96, 455
(2) Taber Oxone Preparation OS 2013, 90, 350
(3) Miyaura Bis(pinacolato)diboron OS 2000, 77, 176
(4) Boeckman Dess Martin Reagent OS 2000, 77, 141
August 28, 2025 at 12:02 PM
Top Ten Organic Syntheses Articles (Volume 65 to present) accessed during 2024
(1) Kelly Carbazole Photoredox Catalyst OS 2019, 96, 455
(2) Taber Oxone Preparation OS 2013, 90, 350
(3) Miyaura Bis(pinacolato)diboron OS 2000, 77, 176
(4) Boeckman Dess Martin Reagent OS 2000, 77, 141
(1) Kelly Carbazole Photoredox Catalyst OS 2019, 96, 455
(2) Taber Oxone Preparation OS 2013, 90, 350
(3) Miyaura Bis(pinacolato)diboron OS 2000, 77, 176
(4) Boeckman Dess Martin Reagent OS 2000, 77, 141
Synthesis of meta-Substituted Benzenes via Mo-Catalyzed Intermolecular Deoxygenative Coupling of Ynones and Allylic Amines
Yi-Zhe Yu, Gang Fang, Hong-Yi Su, and Chun-Xiang Zhuo (zhuolab.xmu.edu.cn)
www.orgsyn.org/demo.aspx?pr...
Yi-Zhe Yu, Gang Fang, Hong-Yi Su, and Chun-Xiang Zhuo (zhuolab.xmu.edu.cn)
www.orgsyn.org/demo.aspx?pr...
August 26, 2025 at 3:46 PM
Synthesis of meta-Substituted Benzenes via Mo-Catalyzed Intermolecular Deoxygenative Coupling of Ynones and Allylic Amines
Yi-Zhe Yu, Gang Fang, Hong-Yi Su, and Chun-Xiang Zhuo (zhuolab.xmu.edu.cn)
www.orgsyn.org/demo.aspx?pr...
Yi-Zhe Yu, Gang Fang, Hong-Yi Su, and Chun-Xiang Zhuo (zhuolab.xmu.edu.cn)
www.orgsyn.org/demo.aspx?pr...
Congratulations to former OS editor Brian M. Stoltz (www.stoltz.caltech.edu), recipient of the 2026 ACS Ernest Guenther Award in the Chemistry of Natural Products
August 26, 2025 at 1:46 PM
Congratulations to former OS editor Brian M. Stoltz (www.stoltz.caltech.edu), recipient of the 2026 ACS Ernest Guenther Award in the Chemistry of Natural Products
Congratulations to OS editor Tehshik Yoon (yoon.chem.wisc.edu), recipient of the 2026 ACS David Evans Award for Advancement and Education of Organic Synthesis
August 26, 2025 at 1:43 PM
Congratulations to OS editor Tehshik Yoon (yoon.chem.wisc.edu), recipient of the 2026 ACS David Evans Award for Advancement and Education of Organic Synthesis
Congratulations to OS editor Sophie Rousseaux (sites.chem.utoronto.ca/rousseaux/), recipient of a 2026 ACS Arthur C. Cope Scholar Award
August 26, 2025 at 1:31 PM
Congratulations to OS editor Sophie Rousseaux (sites.chem.utoronto.ca/rousseaux/), recipient of a 2026 ACS Arthur C. Cope Scholar Award
Congratulations to OS editor Darren J. Dixon (dixon.chem.ox.ac.uk/darren.html), recipient of a 2026 ACS Arthur C. Cope Scholar Award
August 26, 2025 at 1:25 PM
Congratulations to OS editor Darren J. Dixon (dixon.chem.ox.ac.uk/darren.html), recipient of a 2026 ACS Arthur C. Cope Scholar Award
Organic Syntheses announces the election of Dr. Kevin M. Maloney, Executive Director and Head of Process Chemistry, Merck Research Laboratories, to the OS Board of Editors.
August 26, 2025 at 1:20 PM
Organic Syntheses announces the election of Dr. Kevin M. Maloney, Executive Director and Head of Process Chemistry, Merck Research Laboratories, to the OS Board of Editors.
Synthesis of α-Aryl Ketones via the Nickel-Catalyzed Hydroacylation of Aryl Alkenes with Aroyl Fluorides
Yoonho Lee, Yujin Jung, Seonhwa Choo, and Kwangmin Shin (www.kmshinlab.com)
www.orgsyn.org/demo.aspx?pr...
Yoonho Lee, Yujin Jung, Seonhwa Choo, and Kwangmin Shin (www.kmshinlab.com)
www.orgsyn.org/demo.aspx?pr...
August 18, 2025 at 12:57 PM
Synthesis of α-Aryl Ketones via the Nickel-Catalyzed Hydroacylation of Aryl Alkenes with Aroyl Fluorides
Yoonho Lee, Yujin Jung, Seonhwa Choo, and Kwangmin Shin (www.kmshinlab.com)
www.orgsyn.org/demo.aspx?pr...
Yoonho Lee, Yujin Jung, Seonhwa Choo, and Kwangmin Shin (www.kmshinlab.com)
www.orgsyn.org/demo.aspx?pr...
The Sixth Organic Syntheses Inc Workshop for Young Investigators on Organic Synthesis and Natural Products Chemistry was held at the UC Santa Barbara Club on August 7 to 9
August 12, 2025 at 12:30 PM
The Sixth Organic Syntheses Inc Workshop for Young Investigators on Organic Synthesis and Natural Products Chemistry was held at the UC Santa Barbara Club on August 7 to 9
Preparation of tBu-MsFluind-Br
Lucas Wagner and Josep Cornella (www.cornellab.com)
www.orgsyn.org/demo.aspx?pr...
Lucas Wagner and Josep Cornella (www.cornellab.com)
www.orgsyn.org/demo.aspx?pr...
July 9, 2025 at 12:18 PM
Preparation of tBu-MsFluind-Br
Lucas Wagner and Josep Cornella (www.cornellab.com)
www.orgsyn.org/demo.aspx?pr...
Lucas Wagner and Josep Cornella (www.cornellab.com)
www.orgsyn.org/demo.aspx?pr...
Ryan Gilmour (www.uni-muenster.de/Chemie.oc/gi...) of University of Münster presented the Org Syn Lecture at MIT on Thursday, April 17th, speaking on “Illuminating Stereoselective Catalysis”
June 27, 2025 at 12:45 PM
Ryan Gilmour (www.uni-muenster.de/Chemie.oc/gi...) of University of Münster presented the Org Syn Lecture at MIT on Thursday, April 17th, speaking on “Illuminating Stereoselective Catalysis”