Steve Mount
ongenetics.bsky.social
Steve Mount
@ongenetics.bsky.social
Steve Mount, Univ. of Maryland.
Interested in gene structure and function, especially pre-mRNA splicing. Bioinformatician and biodata flaneur.
Reposted by Steve Mount
I'm excited to share our latest publication on co-transcriptional RNA folding in a eukaryote! Great work by Leo Schärfen with collaboration from Isaac Vock and Matt Simon! @leoschaerfen.bsky.social @mattdsimon.bsky.social
Take a peek here authors.elsevier.com/a/1kpxo_Oylr...
authors.elsevier.com
March 26, 2025 at 12:12 PM
Reposted by Steve Mount
OpenSpliceAI: An efficient, modular implementation of SpliceAI enabling easy retraining on non-human species https://www.biorxiv.org/content/10.1101/2025.03.20.644351v1
March 24, 2025 at 3:33 AM
Reposted by Steve Mount
February 26, 2025 at 2:58 PM
"Children will die if RFK Jr. is put in charge of HHS."
November 30, 2024 at 1:31 AM
Reposted by Steve Mount
A new blog post up today, my first since quitting @forbes. Read it here with no paywall or ads: genome.fieldofscience.com/2024/11/rfk-...
RFK Jr. is not a serious person. Don't take him seriously.
Well, president-elect Trump has announced that he will nominate Robert F. Kennedy Jr. to be the Secretary of Health and Human Services (HHS)...
genome.fieldofscience.com
November 29, 2024 at 6:58 PM
Reposted by Steve Mount
I feel like this is validation when people ask me about alternative splicing and then the first thing I ask them is their read depth...

RNA sequencing depth guidelines for the study of alternative splicing www.biorxiv.org/content/10.1...
RNA sequencing depth guidelines for the study of alternative splicing
A key parameter in the experimental design of RNA-seq projects is the choice of sequencing depth. Considering a limited budget, one needs to find a tradeoff between the number of samples and the sensi...
www.biorxiv.org
November 25, 2024 at 6:38 PM
Reposted by Steve Mount
Published online today @jcellbiol.bsky.social you will find our latest work on Cajal bodies. 😅🎉 It has been a joy to work with Chuyue Zhang, Dahyana Arias Escayola, and colleagues! doi.org/10.1083/jcb....
#RNAsky #RNAbiology
Identification of coilin interactors reveals coordinated control of Cajal body number and structure
This study identifies new Cajal body components and tests their roles in the formation of these nuclear membraneless organelles. Imbalances in the levels o
doi.org
November 27, 2024 at 6:48 PM
My first post here.
So far, no garbage notifications or random turds in my feed.
I joined yesterday evening, followed 97 people, and now (10 am) 19 people I know have followed me back.
It looks like this is going to be like science Twitter in the old days.
😂
November 24, 2024 at 3:08 PM