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olivierfesneau.bsky.social
@olivierfesneau.bsky.social
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acir-org.bsky.social
Fesneau et al. showed that in HNSCC and CRC tumors, expression of the inhibitor NKG2A, a receptor for HLA-E that is associated with poor prognosis for many solid cancers, was upregulated upon differentiation of [...] bit.ly/3D2hZCb   ‪@olivierfesneau.bsky.social‬
December 5, 2024 at 4:45 PM
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bernardafox.bsky.social
💥 #Cancer #Vaccines in combo IO are #HOT!! Wasn’t on Bsky 11/8 so posting now/@ #SITC2024 we reported tripling of response rate & progression-free survival #PFS in #HNSCC + COOL #TCR #LAG3 & #DarkMatter data @patrickhwumd.bsky.social @chrystalpaulos.bsky.social www.einpresswire.com/article/7584...
November 30, 2024 at 8:12 PM
olivierfesneau.bsky.social
Happy to share my new paper done under the mentorship of Dr. Thomas Duhen at #EACRI, bringing new insights about the role of IL-12 in tumor immunity.
#FinishCancer

www.nature.com/articles/s41...
IL-12 drives the expression of the inhibitory receptor NKG2A on human tumor-reactive CD8 T cells - Nature Communications
Effective strategies to enhance T cell anti-tumor cytotoxicity are pivotal to improve treatment outcomes. By analyzing tumor samples from patients with head and neck or colon cancers, here the authors...
www.nature.com
November 26, 2024 at 7:28 PM