Noah Hamlish
@nxhamlish.bsky.social
Grad student in Schepartz Lab @ UC Berkeley | Chicagoan to my core
Reposted by Noah Hamlish
✨ New C-GEM preprint
E. coli ribosomes support translation of (R) and (S) β2-hydroxyacids in vitro: a structural and biochemical study
Congrats @c-majumdar.bsky.social, @alexandra-kent.bsky.social, @nxhamlish.bsky.social, Cathy, Katie, Alanna, and @jhdcate.bsky.social!
chemrxiv.org/engage/chemr...
E. coli ribosomes support translation of (R) and (S) β2-hydroxyacids in vitro: a structural and biochemical study
Congrats @c-majumdar.bsky.social, @alexandra-kent.bsky.social, @nxhamlish.bsky.social, Cathy, Katie, Alanna, and @jhdcate.bsky.social!
chemrxiv.org/engage/chemr...
Escherichia coli ribosomes support translation of (R) and (S) β2-hydroxyacids in vitro: a structural and biochemical study
The ribosomal incorporation of backbone-modified amino acid analogs into peptides and proteins enables the programmed synthesis of sequence-defined biopolymers with tunable properties. However, the su...
chemrxiv.org
May 19, 2025 at 4:29 PM
✨ New C-GEM preprint
E. coli ribosomes support translation of (R) and (S) β2-hydroxyacids in vitro: a structural and biochemical study
Congrats @c-majumdar.bsky.social, @alexandra-kent.bsky.social, @nxhamlish.bsky.social, Cathy, Katie, Alanna, and @jhdcate.bsky.social!
chemrxiv.org/engage/chemr...
E. coli ribosomes support translation of (R) and (S) β2-hydroxyacids in vitro: a structural and biochemical study
Congrats @c-majumdar.bsky.social, @alexandra-kent.bsky.social, @nxhamlish.bsky.social, Cathy, Katie, Alanna, and @jhdcate.bsky.social!
chemrxiv.org/engage/chemr...
Feels hard to write about anything other than *gestures broadly* but I did just finish the roll of parafilm I bought at the start of my PhD. Can I redeem this for a fun shirt or a donut?
February 20, 2025 at 2:29 AM
Feels hard to write about anything other than *gestures broadly* but I did just finish the roll of parafilm I bought at the start of my PhD. Can I redeem this for a fun shirt or a donut?
Reposted by Noah Hamlish
✨ New from C-GEM in ACS Central Science:
Thioesters Support Efficient Protein Biosynthesis by the Ribosome
pubs.acs.org/doi/10.1021/...
Congrats to Alexandra & Jacob, along with Isaac, Jess, @alexsolivan.bsky.social, @nxhamlish.bsky.social, Katie, Alanna, Jamie, and Scott!
#NSFfunded @pubs.acs.org
Thioesters Support Efficient Protein Biosynthesis by the Ribosome
pubs.acs.org/doi/10.1021/...
Congrats to Alexandra & Jacob, along with Isaac, Jess, @alexsolivan.bsky.social, @nxhamlish.bsky.social, Katie, Alanna, Jamie, and Scott!
#NSFfunded @pubs.acs.org
Thioesters Support Efficient Protein Biosynthesis by the Ribosome
Thioesters are critical chemical intermediates in numerous extant biochemical reactions and are invoked as key reagents during prebiotic peptide synthesis on an evolving Earth. Here we asked if a thio...
pubs.acs.org
February 3, 2025 at 6:31 PM
✨ New from C-GEM in ACS Central Science:
Thioesters Support Efficient Protein Biosynthesis by the Ribosome
pubs.acs.org/doi/10.1021/...
Congrats to Alexandra & Jacob, along with Isaac, Jess, @alexsolivan.bsky.social, @nxhamlish.bsky.social, Katie, Alanna, Jamie, and Scott!
#NSFfunded @pubs.acs.org
Thioesters Support Efficient Protein Biosynthesis by the Ribosome
pubs.acs.org/doi/10.1021/...
Congrats to Alexandra & Jacob, along with Isaac, Jess, @alexsolivan.bsky.social, @nxhamlish.bsky.social, Katie, Alanna, Jamie, and Scott!
#NSFfunded @pubs.acs.org
I'm gonna be co-op-ing with the chemical biotechnologies group at Merck this summer and early fall!
Really excited for this opportunity and grateful for all the people who helped make this possible
If youre in NYC, hit me up to discuss protein engineering, synbio, and genetic code expansion!
January 25, 2025 at 1:45 AM
I'm gonna be co-op-ing with the chemical biotechnologies group at Merck this summer and early fall!
Really excited for this opportunity and grateful for all the people who helped make this possible
If youre in NYC, hit me up to discuss protein engineering, synbio, and genetic code expansion!
Reposted by Noah Hamlish
📰 New from C-GEM in ACS Central Science!
An exciting collaboration with our friends at Amgen and Schrödinger to demonstrate incorporation of multiple extended backbones in a protein in vivo ✨
Congrats to @nxhamlish.bsky.social and the rest of the team!
#NSFfunded
pubs.acs.org/doi/10.1021/...
An exciting collaboration with our friends at Amgen and Schrödinger to demonstrate incorporation of multiple extended backbones in a protein in vivo ✨
Congrats to @nxhamlish.bsky.social and the rest of the team!
#NSFfunded
pubs.acs.org/doi/10.1021/...
Incorporation of Multiple β<sup>2</sup>-Hydroxy Acids into a Protein <italic toggle="yes">In Vivo</italic> Using an Orthogonal Aminoacyl-tRNA Synthetase
The programmed synthesis of sequence-defined biomaterials whose monomer backbones diverge from those of canonical α-amino acids represents the next frontier in protein and biomaterial evolution. Such ...
pubs.acs.org
April 23, 2024 at 5:20 PM
📰 New from C-GEM in ACS Central Science!
An exciting collaboration with our friends at Amgen and Schrödinger to demonstrate incorporation of multiple extended backbones in a protein in vivo ✨
Congrats to @nxhamlish.bsky.social and the rest of the team!
#NSFfunded
pubs.acs.org/doi/10.1021/...
An exciting collaboration with our friends at Amgen and Schrödinger to demonstrate incorporation of multiple extended backbones in a protein in vivo ✨
Congrats to @nxhamlish.bsky.social and the rest of the team!
#NSFfunded
pubs.acs.org/doi/10.1021/...