Nollen Lab
@nollenlab.bsky.social
Using C. elegans to study Molecular Neurobiology of Aging. Lab at the European Research Institute for the Biology of Ageing in Groningen, the Netherlands (ERIBA, UMCG)
🚨 New preprint alert! We uncovered a link between Parkinson’s protein α-synuclein and fat metabolism. α-syn inclusions disrupt lipid droplets and deplete TAGs during aging & MCFAs restore movement in α-synuclein worms.
👉 Targeting fat metabolism could help to combat Parkinson’s! shorturl.at/2mVG6
👉 Targeting fat metabolism could help to combat Parkinson’s! shorturl.at/2mVG6
Condensate-Driven Triglyceride Depletion Links α-Synuclein to Mitochondrial Dysfunction
Inclusions of α-Synuclein (αSyn) characterize multiple age-related neurodegenerative diseases, including Parkinson’s disease (PD) and Multiple System Atrophy (MSA). While interactions between αSyn and...
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November 21, 2025 at 8:15 AM
🚨 New preprint alert! We uncovered a link between Parkinson’s protein α-synuclein and fat metabolism. α-syn inclusions disrupt lipid droplets and deplete TAGs during aging & MCFAs restore movement in α-synuclein worms.
👉 Targeting fat metabolism could help to combat Parkinson’s! shorturl.at/2mVG6
👉 Targeting fat metabolism could help to combat Parkinson’s! shorturl.at/2mVG6
Last week was a very proud moment for the Nollen lab: Lale Güngördü successfully defended her PhD thesis, “Modifying TDP-43 Toxicity”! 🎓🔥
Congratulations, Dr. Güngördü! We are so proud of you!
We had a fantastic day celebrating this milestone and we can’t wait to see what she will achieve next! ✨🔬
Congratulations, Dr. Güngördü! We are so proud of you!
We had a fantastic day celebrating this milestone and we can’t wait to see what she will achieve next! ✨🔬
November 6, 2025 at 3:01 PM
Last week was a very proud moment for the Nollen lab: Lale Güngördü successfully defended her PhD thesis, “Modifying TDP-43 Toxicity”! 🎓🔥
Congratulations, Dr. Güngördü! We are so proud of you!
We had a fantastic day celebrating this milestone and we can’t wait to see what she will achieve next! ✨🔬
Congratulations, Dr. Güngördü! We are so proud of you!
We had a fantastic day celebrating this milestone and we can’t wait to see what she will achieve next! ✨🔬
Excited to announce that Suzanne Couzijn and Anna Ainslie have received a grant from Stichting ParkinsonFonds🎉👏 for their project “Protecting against alpha-synuclein toxicity at molecular and physiological levels”. They will investigate the mechanisms driving alpha-synuclein toxicity in C. elegans🪱🧠
August 28, 2025 at 9:04 AM
Excited to announce that Suzanne Couzijn and Anna Ainslie have received a grant from Stichting ParkinsonFonds🎉👏 for their project “Protecting against alpha-synuclein toxicity at molecular and physiological levels”. They will investigate the mechanisms driving alpha-synuclein toxicity in C. elegans🪱🧠
🌍 Today in the Nollen Lab, we are celebrating the International Day of Women and Girls in Science! 🔬🧪 Here's to a future where every girl feels empowered to lead in science. ⚛️
#WomenInScience #STEMinspiration #IDWGS
@ellennollen.bsky.social
#WomenInScience #STEMinspiration #IDWGS
@ellennollen.bsky.social
February 11, 2025 at 1:52 PM
🌍 Today in the Nollen Lab, we are celebrating the International Day of Women and Girls in Science! 🔬🧪 Here's to a future where every girl feels empowered to lead in science. ⚛️
#WomenInScience #STEMinspiration #IDWGS
@ellennollen.bsky.social
#WomenInScience #STEMinspiration #IDWGS
@ellennollen.bsky.social
We’re the Nollen Lab, and we’re excited to join the scientific community on Blue Sky!🌞 Our lab uses the nematode worm C. elegans to understand the molecular neurobiology of ageing and neurodegerative diseases 🧠🔬🧪🪱
#Neurobiology #AgingScience #Parkinsons #ALS #Alzheimer #Metabolism #Ageing #Celegans
#Neurobiology #AgingScience #Parkinsons #ALS #Alzheimer #Metabolism #Ageing #Celegans
January 9, 2025 at 12:06 PM
We’re the Nollen Lab, and we’re excited to join the scientific community on Blue Sky!🌞 Our lab uses the nematode worm C. elegans to understand the molecular neurobiology of ageing and neurodegerative diseases 🧠🔬🧪🪱
#Neurobiology #AgingScience #Parkinsons #ALS #Alzheimer #Metabolism #Ageing #Celegans
#Neurobiology #AgingScience #Parkinsons #ALS #Alzheimer #Metabolism #Ageing #Celegans