Nikki Moreland
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njmoreland.bsky.social
Nikki Moreland
@njmoreland.bsky.social
Infection and Immunity | Vaccines and Antibodies | Strep A and rheumatic fever | Research scientist and Associate Professor in Aotearoa New Zealand
So many important insights on #StrepA immunity in this huge piece work by @alexjkeeley.bsky.social @thushan-desilva.bsky.social and the team in #TheGambia. A real privilege to have played a small role from down-under
August 8, 2025 at 10:53 PM
There are multiple reports of dramatic reductions followed by surges in invasive Strep A disease post-pandemic, and now here is one on rheumatic fever, with incidence mirroring superficial infections in the community in Auckland New Zealand - led by Julie Bennett
www.tandfonline.com/doi/10.1080/...
Pandemic mitigations reveal an association between superficial group A streptococcal infections and acute rheumatic fever incidence in Auckland New Zealand
Published in Emerging Microbes & Infections (Vol. 14, No. 1, 2025)
www.tandfonline.com
August 5, 2025 at 1:12 AM
This deep dive into the clinical phenotype of rheumatic fever highlights extreme diversity in presenting symptoms. An important observation from the START study, and highlights why better diagnostic tests are needed 🧪 @annapralph.bsky.social @rhcmcg.bsky.social

bmjopen.bmj.com/content/15/7...
July 22, 2025 at 5:44 AM
The complete spectrum of serious #StrepA disease was observed in Auckland in 2023 - a mighty lab-based enhanced surveillance effort led by Andrew Fox-Lewis and Rachel Webb www.thelancet.com/journals/lan...
Capturing the complete clinical spectrum and incidence of severe acute Group A Streptococcus (GAS) disease: a population-based study in Auckland, New Zealand
This study demonstrates that the complete clinical spectrum of severe acute GAS disease occurs in Auckland and is associated with a substantial health and economic burden. The high incidence and entir...
www.thelancet.com
July 9, 2025 at 11:59 PM
Reposted by Nikki Moreland
New preprint alert 🚨

My team and I are pleased to share our most recent story about how bacterial pathogen (Streptococcus pyogenes, Strep A) exposure induces antibody responses against glycan and protein antigens.

For paper: SSRN ssrn.com/abstract=519...
biorxiv : doi: doi.org/10.1101/2025...
April 4, 2025 at 12:01 AM
Reposted by Nikki Moreland
Super excited announce funded @wellcometrust.bsky.social extend #StrepA Human challenge inc. transfer to Gambia & identify correlates of protection. Great team @joshosowicki.bsky.social @precisionvaxlab.bsky.social @njmoreland.bsky.social @thushan-desilva.bsky.social y.social & others not on Bluesky
March 7, 2025 at 10:27 AM
Reposted by Nikki Moreland
📣Research Technician job alert! Needed to support our #iSpyLIFE field work and #strep biobanking. www.imperial.ac.uk/jobs/search-...
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
www.imperial.ac.uk
January 16, 2025 at 2:16 AM
Following relaxation of #COVID19 restrictions surges in infections from respiratory pathogens like RSV and #StrepA have been seen in many countries including Aotearoa New Zealand.
Did waning immunity contribute? We explored this concept in our latest work, see 🧵 academic.oup.com/jid/advance-...
Decline of antibodies to major viral and bacterial respiratory pathogens during the COVID-19 pandemic
Antibodies to respiratory syncytial virus and Group A Streptococcus waned significantly in a longitudinal cohort throughout the pandemic. This waning may h
academic.oup.com
December 15, 2024 at 10:17 PM
Reposted by Nikki Moreland
This #StrepA paper was a LONG labour of love from a great team 😊 Equal first & senior author credits buried at the very end, so I want to highlight the critical contributions of Dr Hannah Frost & @njmoreland.bsky.social & Dr Danika Hill @precisionvaxlab.bsky.social rdcu.be/d2gBV
Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infections
Nature Communications - Streptococcus pyogenes is a deadly bacteria without a vaccine. Here, researchers measured antibodies in serum and saliva from a strep throat human challenge trial. Baseline...
rdcu.be
December 3, 2024 at 10:37 PM
Finally jumping into 🦋 - and what better way to do than highlighting this super thread. Wonderful to have been involved in this study with our Strep A friends across the Tasman
🎉 I'm a #newPI , and I'm so excited to share our new paper out in Nature Comms today! 🧵
rdcu.be/d2gBV
Quick intro for the new followers:
I'm from Monash Uni in Melbourne, and we study T and B cell responses to viruses, bacteria & parasites with the goal of improving vaccines. #ImmunoSky #MicroSky
December 4, 2024 at 10:48 AM