Thomas Lab at University of Illinois Chicago
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nitricoxidelab.bsky.social
Thomas Lab at University of Illinois Chicago
@nitricoxidelab.bsky.social
The goal of our lab is to elucidate fundamental mechanisms of nitric oxide signaling to explain the etiologies of diseases including cancers. Our discoveries have established that NO is an endogenously produced epigenetic regulatory molecule.
A new paradigm shift in NO signaling. Our latest research is now published in @NatureComms! Discover how NO epigenetically controls DNA methylation to regulate gene expression and cellular function. nam04.safelinks.protection.outlook.com?url=https%3A...
#NitricOxide, #Epigenetics, #DNAMethylation
Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome
Nature Communications - Here, the authors suggest that nitric oxide (NO) is an endogenous epigenetic regulator of gene expression by inhibiting DNA demethylation enzymes (TET and ALKBH2) and...
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February 18, 2025 at 6:59 PM