Ninad Oak, PhD
@ninadoak.bsky.social
Lead Bioinformatics Research Scientist @StJudeResearch | Pediatric Cancer Predisposition | Views are my own | Also cricket!
ninadoak.com/sketchnotes
ninadoak.com/sketchnotes
Proud to share this work published in the prestigious Journal of Clinical Oncology. We report a new cancer predisposition gene, SMARCAL1, in pediatric bone cancer, osteosarcoma.
📄 Oak et al., 2025 — ascopubs.org/doi/10.1200/...
#cancer #predisposition #osteosarcoma #discovery
📄 Oak et al., 2025 — ascopubs.org/doi/10.1200/...
#cancer #predisposition #osteosarcoma #discovery
Investigation of DNA Damage Response Genes Validates the Role of DNA Repair in Pediatric Cancer Risk and Identifies <i>SMARCAL1</i> as a Novel Osteosarcoma Predisposition Gene
PURPOSERecent studies reveal that 5%-18% of children with cancer harbor pathogenic variants
in known cancer-predisposing genes. However, DNA damage repair (DDR) genes, which
are frequently somatically...
ascopubs.org
November 20, 2025 at 3:59 PM
Proud to share this work published in the prestigious Journal of Clinical Oncology. We report a new cancer predisposition gene, SMARCAL1, in pediatric bone cancer, osteosarcoma.
📄 Oak et al., 2025 — ascopubs.org/doi/10.1200/...
#cancer #predisposition #osteosarcoma #discovery
📄 Oak et al., 2025 — ascopubs.org/doi/10.1200/...
#cancer #predisposition #osteosarcoma #discovery
Super-proud of our team lifting the prestigious 'Golden Floppy Disk' award at St. Jude Biohackathon 2025 🏆 with Genesis: Multi-Modal Agentic AI for Cancer Variant Effect Prioritization.
github.com/stjude-bioha...
github.com/stjude-bioha...
October 13, 2025 at 6:01 PM
Super-proud of our team lifting the prestigious 'Golden Floppy Disk' award at St. Jude Biohackathon 2025 🏆 with Genesis: Multi-Modal Agentic AI for Cancer Variant Effect Prioritization.
github.com/stjude-bioha...
github.com/stjude-bioha...
Reposted by Ninad Oak, PhD
Our new study in @ascocancer.bsky.social uncovers SMARCAL1 as a novel osteosarcoma predisposition gene, confirming DNA repair’s key role in childhood cancer risk.
@stjuderesearch.bsky.social @clevelandclinic.bsky.social
👉 ascopubs.org/doi/10.1200/...
#PediatricCancer #Genomics
@stjuderesearch.bsky.social @clevelandclinic.bsky.social
👉 ascopubs.org/doi/10.1200/...
#PediatricCancer #Genomics
Investigation of DNA damage response genes validates the role of DNA repair in pediatric cancer risk and identifies <i>SMARCAL1</i> as novel osteosarcoma predisposition gene
BackgroundRecent studies reveal that 5-18% of children with cancer harbor pathogenic variants
in known cancer predisposing genes. However, DNA damage repair (DDR) genes, which
are frequently somatical...
ascopubs.org
October 10, 2025 at 2:32 AM
Our new study in @ascocancer.bsky.social uncovers SMARCAL1 as a novel osteosarcoma predisposition gene, confirming DNA repair’s key role in childhood cancer risk.
@stjuderesearch.bsky.social @clevelandclinic.bsky.social
👉 ascopubs.org/doi/10.1200/...
#PediatricCancer #Genomics
@stjuderesearch.bsky.social @clevelandclinic.bsky.social
👉 ascopubs.org/doi/10.1200/...
#PediatricCancer #Genomics
Our new study in @ascocancer.bsky.social uncovers SMARCAL1 as a novel osteosarcoma predisposition gene, confirming DNA repair’s key role in childhood cancer risk.
@stjuderesearch.bsky.social @clevelandclinic.bsky.social
👉 ascopubs.org/doi/10.1200/...
#PediatricCancer #Genomics
@stjuderesearch.bsky.social @clevelandclinic.bsky.social
👉 ascopubs.org/doi/10.1200/...
#PediatricCancer #Genomics
Investigation of DNA damage response genes validates the role of DNA repair in pediatric cancer risk and identifies <i>SMARCAL1</i> as novel osteosarcoma predisposition gene
BackgroundRecent studies reveal that 5-18% of children with cancer harbor pathogenic variants
in known cancer predisposing genes. However, DNA damage repair (DDR) genes, which
are frequently somatical...
ascopubs.org
October 10, 2025 at 2:32 AM
Our new study in @ascocancer.bsky.social uncovers SMARCAL1 as a novel osteosarcoma predisposition gene, confirming DNA repair’s key role in childhood cancer risk.
@stjuderesearch.bsky.social @clevelandclinic.bsky.social
👉 ascopubs.org/doi/10.1200/...
#PediatricCancer #Genomics
@stjuderesearch.bsky.social @clevelandclinic.bsky.social
👉 ascopubs.org/doi/10.1200/...
#PediatricCancer #Genomics
Organizing the HSRI lecture series has been one of the most rewarding experience. Watching high school students gain confidence in genomics and data science and seeing their curiosity grow was inspiring. Excited to see our story featured in St. Jude Progress!
www.stjude.org/research/pro...
www.stjude.org/research/pro...
Datasets inspire mindsets for future scientists
Discover how St. Jude scientists are inspiring future researchers through a data science seminar series for high school students.
www.stjude.org
August 22, 2025 at 2:55 AM
Organizing the HSRI lecture series has been one of the most rewarding experience. Watching high school students gain confidence in genomics and data science and seeing their curiosity grow was inspiring. Excited to see our story featured in St. Jude Progress!
www.stjude.org/research/pro...
www.stjude.org/research/pro...
Reposted by Ninad Oak, PhD
Ninad Oak, PhD, Lead Bioinformatics Research Scientist at St. Jude, uses sketchnoting to make science accessible. By visually summarizing research talks and papers, he simplifies complex ideas—a practice he now incorporates into mentoring students. @ninadoak.bsky.social
July 30, 2025 at 5:27 PM
Ninad Oak, PhD, Lead Bioinformatics Research Scientist at St. Jude, uses sketchnoting to make science accessible. By visually summarizing research talks and papers, he simplifies complex ideas—a practice he now incorporates into mentoring students. @ninadoak.bsky.social
Reposted by Ninad Oak, PhD
It's that time of year! Submit your fabulous 🧬 science for #ASHG25 in Boston! ABSTRACTS DUE 🗓️ JUNE 9! We'd love to see you there @geneticssociety.bsky.social
Submit your science and remind your friends to do the same!
www.ashg.org/meetings/202...
Submit your science and remind your friends to do the same!
www.ashg.org/meetings/202...
Abstracts
Abstract submission for ASHG 2025. We encourage you to submit your latest research on human genetics and genomics for programming at the ASHG 2025 Annual Meeting.
www.ashg.org
May 27, 2025 at 2:23 PM
It's that time of year! Submit your fabulous 🧬 science for #ASHG25 in Boston! ABSTRACTS DUE 🗓️ JUNE 9! We'd love to see you there @geneticssociety.bsky.social
Submit your science and remind your friends to do the same!
www.ashg.org/meetings/202...
Submit your science and remind your friends to do the same!
www.ashg.org/meetings/202...
Excited to share our new preprint with some cool new discoveries. Please let us know what you think.
Germline variation in DNA damage repair genes in children with cancer: Unveiling SMARCAL1 as novel osteosarcoma predisposition gene https://www.medrxiv.org/content/10.1101/2025.05.12.25325832v1
May 14, 2025 at 11:01 PM
Excited to share our new preprint with some cool new discoveries. Please let us know what you think.
St. Jude Cancer Predisposition Symposium:
"At the Crossroads: Intersection of Germline Predisposition & Pediatric Oncology Clinical Care & Research"
Register today!
#cancer #predisposition #symposium #genetics
www.stjude.org/education-tr...
"At the Crossroads: Intersection of Germline Predisposition & Pediatric Oncology Clinical Care & Research"
Register today!
#cancer #predisposition #symposium #genetics
www.stjude.org/education-tr...
St. Jude Cancer Predisposition Symposium
The Cancer Predisposition Symposium will convene leading experts to explore cutting-edge advancements in genetic predisposition to cancer, fostering accelerated progress in this critical area.
www.stjude.org
April 8, 2025 at 11:25 PM
St. Jude Cancer Predisposition Symposium:
"At the Crossroads: Intersection of Germline Predisposition & Pediatric Oncology Clinical Care & Research"
Register today!
#cancer #predisposition #symposium #genetics
www.stjude.org/education-tr...
"At the Crossroads: Intersection of Germline Predisposition & Pediatric Oncology Clinical Care & Research"
Register today!
#cancer #predisposition #symposium #genetics
www.stjude.org/education-tr...
#HIRING
St. Jude leads pediatric cancer care in the world and harbors one of the largest pediatric cancer genomics dataset.
We have a faculty position open in the Division of Cancer Predisposition.
stjude-careers.employeereferrals.com/jobs/r4gGKH0...
#Faculty #cancer #genetics #stjude #jobs
St. Jude leads pediatric cancer care in the world and harbors one of the largest pediatric cancer genomics dataset.
We have a faculty position open in the Division of Cancer Predisposition.
stjude-careers.employeereferrals.com/jobs/r4gGKH0...
#Faculty #cancer #genetics #stjude #jobs
February 20, 2025 at 5:29 PM
It's ASHG time!! What?? In Spring? Are you sure??
Yess, that's right! ASHG has a spring virtual meeting with a focus on Cancer Genetics! Register today for a front seat.
#ashg #virtual #meeting #genetics #cancer
Yess, that's right! ASHG has a spring virtual meeting with a focus on Cancer Genetics! Register today for a front seat.
#ashg #virtual #meeting #genetics #cancer
This spring is heating up with our Virtual Symposium!🔥Happening April 8-9, this CME-eligible event focusing on Cancer Genetics is a can't-miss for those interested in modern approaches to the prediction and evolution of cancer. 🎫Secure your tickets today: learning.ashg.org/p/2025-sprin... #ASHG
February 20, 2025 at 12:42 AM