Natasha Golovchenko
@nbgolovchenko.bsky.social
Postdoc at University of Michigan studying IBD, mucosal immunology, epithelial pathobiology | she/her
Thanks to @edelblumlab.bsky.social for being a wonderful mentor and to @saraalonsomera.bsky.social for being the best partner in crime since the very beginning! 🎓🔬🎉
There are few things better than celebrating milestones with your wonderful mentees! Congrats to @saraalonsomera.bsky.social & @nbgolovchenko.bsky.social on their graduation today. These two started during #COVID lockdown, moved to #NYC and will have made lasting contributions to the #gdTcell field🤩
May 15, 2025 at 1:08 AM
Thanks to @edelblumlab.bsky.social for being a wonderful mentor and to @saraalonsomera.bsky.social for being the best partner in crime since the very beginning! 🎓🔬🎉
Reposted by Natasha Golovchenko
If you read our #ScienceImmunology paper and want to know how the #microbiota induces #CD39 to promote a #gdTcell #immunoregulatory phenotype, check out our new #preprint!
Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling
Intraepithelial lymphocytes expressing the γδ T cell receptor (γδ IEL) provide continuous surveillance of the intestinal epithelium. We report that mice harboring a microbiota-specific hyperproliferat...
www.biorxiv.org
March 25, 2025 at 8:15 PM
If you read our #ScienceImmunology paper and want to know how the #microbiota induces #CD39 to promote a #gdTcell #immunoregulatory phenotype, check out our new #preprint!
Reposted by Natasha Golovchenko
#Bluetorial: In our latest paper on #gdTcells and #IBD in #ScienceImmunology we found that γδ IEL number and regulatory function are severely compromised BEFORE ileal inflammation occurs, suggesting that γδ IELs may maintain IEL homeostasis in response to a pro-inflammatory microenvironment. 1/n
two men are riding a bicycle with a basket on it .
ALT: two men are riding a bicycle with a basket on it .
media.tenor.com
March 22, 2025 at 8:05 PM
#Bluetorial: In our latest paper on #gdTcells and #IBD in #ScienceImmunology we found that γδ IEL number and regulatory function are severely compromised BEFORE ileal inflammation occurs, suggesting that γδ IELs may maintain IEL homeostasis in response to a pro-inflammatory microenvironment. 1/n
Reposted by Natasha Golovchenko
📚NEW #gdTcell PAPER ALERT! Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis | Science Immunology
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis
Multiple layers of γδ IEL dysregulation and loss of their immunosuppressive capacity occur before the onset of chronic ileitis.
www.science.org
March 21, 2025 at 6:14 PM
📚NEW #gdTcell PAPER ALERT! Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis | Science Immunology
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Reposted by Natasha Golovchenko
Congratulations to Dr. Sara Alonso on a spectacular defense! 👏 🍾 Sara is a powerhouse of #gdTcell #immunometabolism data in the lab. We can’t wait to share the #preprint of her thesis work on #gdTcells and #microbiota with you later this week. @sinaiimmuno.bsky.social
March 18, 2025 at 10:06 PM
Congratulations to Dr. Sara Alonso on a spectacular defense! 👏 🍾 Sara is a powerhouse of #gdTcell #immunometabolism data in the lab. We can’t wait to share the #preprint of her thesis work on #gdTcells and #microbiota with you later this week. @sinaiimmuno.bsky.social