Natural Product Reports
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natprodreports.rsc.org
Natural Product Reports
@natprodreports.rsc.org
High impact, critical reviews in natural products research and related areas from RSC Publishing.

Published by @rsc.org 🌐 Website: rsc.li/natprodreports
📢Our latest issue is now online!

Check out the review behind the front cover by Jun Deng & co. from Nankai University looking at the recent progress in [5+2] cycloaddition reactions for natural product synthesis #natprod #orgchem

pubs.rsc.org/en/content/a...
November 12, 2025 at 3:13 PM
Be sure to read this Highlight from Qi Zhang & co. at Jiangxi Normal University in our latest issue looking at para-Quinone methide mediated enzymatic transformations in natural product biosynthesis #secmet #natprod

Find the full article here🔽
para-Quinone methides in natural product biosynthesis
Covering: up to 2025 para-Quinone methides (p-QMs) are highly reactive Michael acceptors with broad applications in organic synthesis, drug development, and materials science. Nature ingeniously…
pubs.rsc.org
November 6, 2025 at 9:30 AM
Check out this review in our latest issue by Zhimin Hu, Jinxin Wang, Wei-Dong Zhang et al. from the Second Military Medical University discussing photo-/electro-chemical catalysis for late-stage functionalization of alkene-containing natural products #natprod #orgchem
Photo-/electro-chemical catalysis: a promising toolkit for late-stage functionalization of alkene-containing natural products
Covering: 2013 to 2024 Alkene-containing natural products (NPs) are abundantly present in plants, animals, and microorganisms. Strategic alkene modification of NPs not only generates diverse chemical…
pubs.rsc.org
November 4, 2025 at 9:56 AM
🔥Take a look at the latest Hot Off the Press article by Robert Hill & @andysuth14.bsky.social on their selection of 32 recent papers covering the latest research in bioorganic chemistry & novel natural products #naturalproducts #natprod

📍 @uofgchem.bsky.social
Hot off the Press
A personal selection of 32 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products such as aragezolone from Auricularia cornea.
pubs.rsc.org
October 29, 2025 at 12:59 PM
Be sure to read this review in our latest issue examining the role of epigenetics in the biosynthesis of secondary metabolites from fungal endophytes from Gang Li, Souvik Kusari et al. at Qingdao University #natprod #secmet

Find in full below👇
Unlocking the metabolic potential of endophytic fungi through epigenetics: a paradigm shift for natural product discovery and plant–microbe interactions
Covering: up to December 2024 Microbial metabolic pathways, including those of endophytic fungi, offer significant potential for synthesizing secondary metabolites, regardless of their ecological…
pubs.rsc.org
October 23, 2025 at 9:30 AM
🔓Don't miss this #OpenAccess Highlight from Andrew Riley at the University of Illinois Chicago in our latest issue discussing semi-synthesis in the exploration of opioid-targeting natural products #natprod

Check out the full article on our website🔽
pubs.rsc.org/en/content/a...
Semi-synthesis in the exploration of opioid-targeting natural products
Covering: up to May 2025 Since the isolation of morphine from opium, chemists have sought to modify its chemical structure in hopes of developing a safer, less addictive pain killer. At the same...
pubs.rsc.org
October 22, 2025 at 7:45 AM
❗Time is running out to nominate for the 2026 @natprodreports.rsc.org Emerging Investigator Lectureship!

⏳Nominations close this weekend so be sure to nominate your rising star in natural product research #natprod #secmet #synbio #chemsky

Details on how to nominate🔽
www.rsc.org/standards-an...
October 17, 2025 at 3:02 PM
📢Our latest issue is now online!

Check out the Highlight behind the cover from Yuwei Zhang, Yihua Chen & co. at the Chinese Academy of Sciences discussing targeted discovery of microbial natural products based on the predictions of both structure & activity #natprod

pubs.rsc.org/en/content/a...
October 15, 2025 at 3:13 PM
🚨There is less than one week left to nominate for the 2026 @natprodreports.rsc.org Emerging Investigator Lectureship! Don't miss the opportunity to recognise a rising star in the field #chemsky #secmet #natprod

⏳Nominations close 19 October

Details on how to nominate🔽
www.rsc.org/standards-an...
October 13, 2025 at 8:24 AM
We are delighted to sponsor the Natural Products in the 'Omics Era' symposium at @pacifichem.bsky.social! #natprod #secmet

Keynote speakers include Michèle Prinsep @waikatouniversity.bsky.social whose research focuses on marine chemical ecology #ORG018

📅19-20 December 2025
🔗https://pacifichem.org
October 11, 2025 at 9:01 AM
🔓Take a look in our latest issue at a #OpenAccess review from Byung-Kwan Cho & co. discussing the use of synthetic interface strategies to engineer modular enzyme assemblies for natural products biosynthesis applications #secmet #natprod

📍KAIST
Engineering modular enzyme assembly: synthetic interface strategies for natural products biosynthesis applications
Covering: 2020 to 2025 Natural products remain indispensable sources of therapeutic and bioactive compounds, yet traditional discovery strategies are constrained by compound rediscovery. Modular…
pubs.rsc.org
October 9, 2025 at 9:03 AM
Be sure to read this review from Hong-Xiang Lou et al. at Shandong University in our latest issue focused on the interconvertible isomerisation of natural products #naturalproducts

Find it in full below🔽
The ballet of nature: the interconvertible isomerisation of natural products
Covering: up to 2025 The diverse interconversion of isomers among natural products (NPs) are shaped by both intrinsic structural characteristics and extrinsic environmental factors, representing a…
pubs.rsc.org
October 7, 2025 at 8:45 AM
⏳There is just under 2 weeks left for you to nominate a rising star in natural product research for the 2026 @natprodreports.rsc.org Emerging Investigator Lectureship! #chemsky #secmet #synbio #naturalproducts

📅Nominations close 19 October

Details on how to nominate🔽
www.rsc.org/standards-an...
October 6, 2025 at 3:20 PM
Don't miss in our latest issue this review, part of our Industrial Perspective themed collection, on the technological developments driving industrial natural product discovery by Nick Allenby & co. at the University of Sunderland #natprod

Check it out in full here👇
pubs.rsc.org/en/content/a...
Technological developments driving industrial natural product discovery
Covering: up to 2025 Bacterial natural products have long been the foundation for many therapeutic agents. However, traditional culture-based approaches to discovering these products have been deprioritised...
pubs.rsc.org
October 3, 2025 at 12:09 PM
Check out this review by Jaehoon Sim et al. from Kyung Hee University in our latest issue highlighting the recent developments in the discovery to synthetic development of natural products targeting the metabolism of amino acids #secmet #natprod

Read in full here🔽
pubs.rsc.org/en/content/a...
Natural products targeting the metabolism of amino acids: from discovery to synthetic development
Covering: up to 2025 Amino acids constitute the essential components of biological systems. Over the recent years, there has been a growing interest in exploring amino acid metabolism as a source of novel...
pubs.rsc.org
October 1, 2025 at 8:56 AM
🔓Take a look in our latest issue at a #OpenAccess review covering the recent advances in the discovery and biosynthesis of RiPP-derived lipopeptides by Shumpei Asamizu #secmet #natprod

📍Kobe University
Recent advances in discovery and biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPP)-derived lipopeptides
Covering: This review summarizes recent advances in the discovery, biosynthesis, and bioactivity of RiPP-derived lipopeptides, covering studies published up to 2024. Ribosomally synthesized and…
pubs.rsc.org
September 29, 2025 at 8:56 AM
Be sure to read this review, part of our Industrial Perspective themed collection, by Stefano Donadio & co. from NAICONS Srl discussing the trends in metabolite discovery from Actinomycetes #secmet #natprod

Find it in full below👇
Trends in metabolite discovery from Actinomycetes
Covering: 2013 to 2023 In this review, we analyzed the scientific literature of the period 2013–2023 that reported novel specialized metabolites from the Actinomycetes, one of the most prolific…
pubs.rsc.org
September 26, 2025 at 11:56 AM
ICYMI: Nominations for the 2026 @natprodreports.rsc.org Emerging Investigator Lectureship are currently open! #chemsky #secmet #naturalproducts #synbio 🧪

⌛Deadline for nominations is 19 October 2025

Details on how to nominate can be found on our website here▶️rsc.li/npr-lectureship
September 24, 2025 at 2:08 PM
Our latest issue has an inside front cover! Don't miss the review behind it from Changsheng Wu et al. at Shandong University looking at recent use of NMR-based metabolomics to explore microbial natural products #natprod

Check out the full article on our website🔽
pubs.rsc.org/en/content/a...
September 22, 2025 at 8:30 AM
📢Our latest issue is now online!

🔓Check out the #OpenAccess review behind the front cover by Xiaofei Shang, Xiaolou Miao, Xiuhui Li, Xiaorong Yang et al. at the Chinese Academy of Agricultural Sciences looking at natural products use in antiparasitic drug discovery

pubs.rsc.org/en/content/a...
September 17, 2025 at 12:54 PM
We are delighted to sponsor the Natural Products in the 'Omics Era' symposium at @pacifichem.bsky.social!

Keynote speakers include Helen Woolner @vicuniwgtn.bsky.social whose research focuses on bioactive natural products from marine bacteria & fungi #ORG018

📅19-20 December 2025
🔗pacifichem.org
September 13, 2025 at 4:01 PM
Be sure to read in our latest issue this review by Hanli Ruan et al. from Huazhong University of Science & Technology discussing the chemical and biological properties of natural resorcylic acid lactones #naturalproducts

Find their full article below👇
The chemical and biological properties of natural resorcylic acid lactones
Covering: 1953 to Feb 2025 Resorcylic acid lactones (RALs) represent a significant category of polyketides characterized by a β-resorcylate unit embedded in a macrolactone ring. Since the discovery…
pubs.rsc.org
September 11, 2025 at 9:07 AM
🔓Take a look at a #OpenAccess review by Gerald Lackner & co. covering recent insights into the biosynthesis and biological activities of the peptide-derived redox cofactor mycofactocin #secmet #natprod

📍 @lacknerlab.bsky.social @unibayreuth.bsky.social @uni-jena.de
Recent insights into the biosynthesis and biological activities of the peptide-derived redox cofactor mycofactocin
Covering: 2011 to 2025 The importance of redox cofactors like nicotinamide adenine dinucleotide or flavin adenine dinucleotide as cofactors for enzymatic reactions in living organisms is widely…
pubs.rsc.org
September 9, 2025 at 11:06 AM
🔥Be sure to read the latest Hot Off the Press article by Robert Hill &
@andysuth14.bsky.social from @uofgchem.bsky.social on their selection of 32 recent papers covering the latest research in bioorganic chemistry & novel natural products #naturalproducts

Find it here🔽
Hot off the Press
A personal selection of 32 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products such as hypbeaone A from Hypericum beanii.
pubs.rsc.org
September 5, 2025 at 12:03 PM
📢Do you know a rising star in natural product research?

We are pleased to announce nominations for the 2026
@natprodreports.rsc.org Emerging Investigator Lectureship are open! #secmet #natprod

📅Nominations close 19 October

Visit our webpage for details on how to nominate🔽
rsc.li/npr-lectureship
September 3, 2025 at 11:17 AM