Mora Ogando
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moraogando.bsky.social
Mora Ogando
@moraogando.bsky.social
120 followers 200 following 16 posts
Postdoctoral researcher at Hillel Adesnik's lab in UC Berkeley. Interested in causally understanding learning and memory
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moraogando.bsky.social
Mora Ogando @moraogando.bsky.social · Aug 5
Thrilled to share our new Adesnik lab paper!!
Using holography in excitatory & inhibitory neurons, we reveal how a single cortical circuit can both complete and cancel predictable sensory activity, sharpening representations
📄https://www.biorxiv.org/content/10.1101/2025.08.02.668307v1
🧵
Reposted by Mora Ogando
danfeldman.bsky.social
New preprint on sensory cortex dysfunction in Scn2a+/- mouse. Profoundly degraded sensory tuning and maps in S1--most dramatic of any ASD model. And rescued in post-critical period adults with CRISPRa.

www.biorxiv.org/content/10.6...
Degraded sensory coding in a mouse model of Scn2a-related disorder and its rescue by CRISPRa gene activation
Heterozygous loss-of-function mutations in SCN2A , a sodium channel gene expressed in cortical pyramidal (PYR) cells, lead to a neurodevelopmental disorder characterized by autism, intellectual disabi...
www.biorxiv.org
December 18, 2025 at 3:57 AM
Reposted by Mora Ogando
yvetteefisher.bsky.social
*First preprint from our lab* !!!!!
How does the brain learn to anchor its internal sense of direction to the outside world? 🧭
led by Mark Plitt @markplitt.bsky.social & Dan Turner-Evans, w/ Vivek Jayaraman:
“Octopamine instructs head direction plasticity” www.biorxiv.org/content/10.6...
Thread ⬇️
Schematic of how ER-EPG plasticity enables the bump of activity in EPGs to accurately track visual cues. As a fly makes a counter-clockwise turn (top to bottom) it will view visual cues (e.g. the sun) from a new angle and the EPG activity bump (red) will swing clockwise around the network by integrating self motion signals with these visual inputs. When the fly faces a different angle, distinct visual ER neurons are active. Plasticity forms a trough of weak synapses (large circles - strong synapses, small circles - weak synapses) that allow ER neurons with distinct visual tuning to move the EPG bump via disinhibition.
December 15, 2025 at 6:26 PM
Reposted by Mora Ogando
mfeller.bsky.social
Come join our new Department of Neuroscience @ucberkeleyofficial.bsky.social as an Assistant Professor! aprecruit.berkeley.edu/JPF05041
Assistant Professor - Molecular, Cellular, and Developmental Neuroscience - Department of Neuroscience
University of California, Berkeley is hiring. Apply now!
aprecruit.berkeley.edu
August 20, 2025 at 2:05 AM
Reposted by Mora Ogando
marlenecohen.bsky.social
One of the joys of being a scientist is the ability to think about a problem for a long time. Our new preprint solves a mystery that has been bugging me since I was a graduate student (which was, ahem, a while ago). 🧪🧠🧵1/
www.biorxiv.org/content/10.1...
Guided by Noise: Correlated Variability Channels Task-Relevant Information in Sensory Neurons
Shared trial-to-trial variability across sensory neurons is reliably reduced when perceptual performance improves, yet this variability is low-dimensional, so it could be ignored by an optimal readout...
www.biorxiv.org
August 15, 2025 at 3:38 PM
moraogando.bsky.social
Thrilled to share our new Adesnik lab paper!!
Using holography in excitatory & inhibitory neurons, we reveal how a single cortical circuit can both complete and cancel predictable sensory activity, sharpening representations
📄https://www.biorxiv.org/content/10.1101/2025.08.02.668307v1
🧵
August 5, 2025 at 4:17 PM