Molecular Omics
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Molecular Omics
@molecularomics.rsc.org

The home of multi-omics and single omics research.

Published by @rsc.org 🌐 Website: rsc.li/MolecularOmics
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Molecular Omics has a new home: we are pleased to announce the journal will be moving from the Royal Society of Chemistry journals portfolio to @oxfordunipress.bsky.social.

Find out more⬇️
bit.ly/3G3URoK
Take a look at research from Jimin Yuan, Lin Jia, Lingyun Dai & co. in our latest issue using proteomics & metabolomics to dissect the BRAF V600E mutation-induced cellular state transition in lung epithelial cells #multiomics

📍Shenzhen Technology University, SUSTech
Proteomic and metabolomic dissection of the BRAF V600E mutation-induced cellular state transition in lung epithelial cells
Non-small cell lung cancer (NSCLC) is the most common subtype of lung cancer, and 4% of NSCLC patients are reported to harbor mutations in BRAF, which encodes a serine/threonine kinase capable of…
pubs.rsc.org
November 12, 2025 at 9:04 AM
🔓Be sure to read in our latest issue this #OpenAccess paper from Erik T. Jansson et al. at @uu.se using proteomics to uncover POMC-specific modulation of metabolic and immune pathways via melanocortin-3 receptor signaling #proteomics

Find it in full on our website🔽
POMC-specific modulation of metabolic and immune pathways via melanocortin-3 receptor signaling
This proteomic study provides a nuanced mechanistic understanding of the signaling processes upon agonist binding to the melanocortin-3 receptor (MC3R). Utilizing thermal proteome profiling (TPP)…
pubs.rsc.org
November 5, 2025 at 1:57 PM
Reposted by Molecular Omics
New publication on @molecularomics.rsc.org 🥳Our work revealed how osteoarthritis reshapes the neuropeptide landscape of the spinal cord in the MIRAT model. This is a nice collaboration with Prof. Eric Troncy Lab, and congrats to Gaoyuan, Marilyn and all co-authors 👏
pubs.rsc.org/en/content/a...
Global spinal cord peptidome profiling in response to osteoarthritis in rats
Osteoarthritis (OA) is a complex and increasingly prevalent condition, affecting an estimated 600 million people worldwide and significantly reducing quality of life. Understanding OA as both an infla...
pubs.rsc.org
October 29, 2025 at 5:55 PM
Don't miss research in our latest issue using mass spectrometry to provide insights into temperature- and time-dependent degradation of mouse tissue proteins by Ramalingam Peraman & co. from NIPER Hajipur #proteomics

Check it out in full below👇
Temperature- and time-dependent degradation of mouse tissue proteins: insights into RNA-binding protein stability via mass spectrometry
In proteomics research, samples are frequently stored at −20 °C and −80 °C for extended periods, and assessing protein stability under these conditions is essential. We evaluated protein stability in…
pubs.rsc.org
October 29, 2025 at 9:04 AM
🔓Check out this #OpenAccess review from Editorial Board member Rosario Domingues & co. at the University of Aveiro looking at the recent advancements in colorectal cancer research driven by lipidomics #lipidomics

Read the full article on our website🔽
Advancing colorectal cancer research through lipidomics
Colorectal cancer (CRC) is currently a global health burden, with staggering worldwide prevalence. CRC is ranked as the third most common and second deadliest cancer worldwide. With rising life…
pubs.rsc.org
October 22, 2025 at 12:49 PM
Take a look in our latest issue at research on how transcriptome and proteome analyses reveal the virulence of the Vibrio alginolyticus effector gene vopR by Min Tao et al. #proteomics #omics

📍Neijiang Normal University
Transcriptome and proteome analyses reveal the virulence of the Vibrio alginolyticus effector gene vopR
Vibrio alginolyticus is an opportunistic infectious pathogen, and its pathogenicity is related to various virulence factors, with the type III secretion system (T3SS) being one of the important…
pubs.rsc.org
October 15, 2025 at 7:45 AM
Be sure to read this paper by Susanta K. Behura & co. from the University of Missouri using multi-omics to investigate mammary gland metabolism and its relevance to the fetoplacental expression of cytokine signalling in caveolin-1 null mice #omics #multiomics

Find in full below👇
Mammary gland metabolism and its relevance to the fetoplacental expression of cytokine signaling in caveolin-1 null mice
Mice lacking caveolin-1 (Cav1), a major protein of the lipid raft of plasma membrane, show deregulated cellular proliferation of the mammary gland and an abnormal fetoplacental communication during…
pubs.rsc.org
October 8, 2025 at 2:31 PM
Don't miss this research in our latest issue looking at how thioridazine induces phospholipid accumulation and necroptosis in parental and tamoxifen-resistant breast cancer cells from Sudhagar Selvaraju et al. at NIPER Guwahati #omics

Check out the article in full here🔽
Thioridazine induces phospholipid accumulation and necroptosis in parental and tamoxifen-resistant breast cancer cells
The development of acquired resistance to tamoxifen poses a significant clinical challenge in breast cancer treatment. Tumour heterogeneity has emerged as a primary reason for the clinical…
pubs.rsc.org
October 1, 2025 at 7:45 AM
📢Issue 5 of Molecular Omics is online!

Check out the paper behind the cover by Patricia Pascual-Vargas, @cbakal.bsky.social & co. from @icr.ac.uk on how integration of focal adhesion morphogenesis and polarity by DOCK5 promotes YAP/TAZ-driven drug resistance in TNBC

pubs.rsc.org/en/content/a...
September 24, 2025 at 12:30 PM
Take a look in our latest issue at an article from Achintya Mohan Goswami, Tanima Saha on how a PPI network identifies interacting pathogenic signaling pathways in Candida albicans

📍University of Kalyani
PPI network identifies interacting pathogenic signaling pathways in Candida albicans
Candida albicans, an opportunistic and systemic infection causing fungus, causes skin, nail, and mucosal layer lesions in healthy individuals and hospital borne catheter-related and nosocomial…
pubs.rsc.org
September 3, 2025 at 8:23 AM
Be sure to read research from our Associate Editor Michael Washburn et al. @kuhospital.bsky.social in our latest issue describing an analysis of FAIMS for the study of affinity-purified protein complexes using the orbitrap ascend tribrid mass spectrometer #proteomics
Analysis of FAIMS for the study of affinity-purified protein complexes using the orbitrap ascend tribrid mass spectrometer
In this study, we analyzed the combination of affinity purification mass spectrometry (AP-MS) with high-field asymmetric waveform ion mobility spectrometry (FAIMS), integrated between nanoLC-MS and…
pubs.rsc.org
August 27, 2025 at 2:21 PM
🔓Don't miss in our latest issue a paper on using a non-targeted LC-IM-MS approach of lipid profiling to prove the geographical origin of strawberries from Markus Fischer & co @uni-hamburg.de #lipidomics

Check out the full article on our website🔽
Lipid profiling: proving the geographical origin of strawberries (Fragaria × ananassa) using a non-targeted LC-IM-MS approach
The strawberry, a globally traded fruit, is a prime example of how geographical origin has become an important marketing factor. Significant price differences between countries of origin make…
pubs.rsc.org
August 20, 2025 at 11:18 AM
Check out research by Jeganathan Manivannan & co from Bharathiar University in our latest issue on human circulatory proteome interaction, oxidative stress-associated signalling and cardiovascular implications during TiO2-NP exposure

Read it in full below👇
Human circulatory proteome interaction, oxidative stress-associated signalling and cardiovascular implications during titanium dioxide nanoparticle (TiO2-NP) exposure
The increasing exposure to nanoparticles raises a concern over their toxicity. Incidentally, reactive oxygen species (ROS) are produced as a result of the nanoparticle's physicochemical…
pubs.rsc.org
August 13, 2025 at 8:13 AM
Take a look in our latest issue at a paper by Dušan Veličković et al. on integrating N-glycan and CODEX imaging to reveal cell-specific protein glycosylation in healthy human lung #glycomics

📍Pacific Northwest National Laboratory & @urochester.bsky.social
Integrating N-glycan and CODEX imaging reveal cell-specific protein glycosylation in healthy human lung
Identifying cell-specific glycan structures in human lungs is critical for understanding the chemistry and mechanisms that guide cell–cell and cell–matrix interactions and determining nuanced…
pubs.rsc.org
July 30, 2025 at 2:10 PM
🔓Be sure to read #OpenAccess research from Clara Belzer & co at @w-u-r.bsky.social & @unileiden.bsky.social describing a multi-omics machine learning classifier for outgrowth of cow's milk allergy in children #multiomics

Find the full article on our website🔽
A multi-omics machine learning classifier for outgrowth of cow's milk allergy in children
Cow's milk protein allergy (CMA) is one of the most common food allergies in children worldwide. However, it is still not well understood why certain children outgrow their CMA and others do not.…
pubs.rsc.org
July 23, 2025 at 11:06 AM
Don't miss the article behind the inside front cover of our latest issue from Preeti Tiwari, Chandan Singh et al. at Banaras Hindu University on metabolomics-based predictive biomarkers of oral cancer and its severity in human patients from North India using saliva

pubs.rsc.org/en/content/a...
July 16, 2025 at 8:39 AM
📢Our latest issue is now online!

🔓Check out the #OpenAccess paper behind the front cover by Kevin Francis, @erinbakerims.bsky.social & co at UNC Chapel Hill revealing cell specific changes during pluripotent differentiation to neural & mesodermal lineages by lipidomics

pubs.rsc.org/en/content/a...
July 9, 2025 at 1:37 PM
🔓Don't miss this #OpenAccess paper in our latest issue by Xinzhou Zhang, Baochun Guo & co from Jinan University on how transcriptomics of serum exosomes reveals lipid metabolic changes as a potential biomarker for evaluation of roxadustat treatment

Check it out below👇
pubs.rsc.org/en/content/a...
Transcriptome profiling of serum exosomes by RNA-Seq reveals lipid metabolic changes as a potential biomarker for evaluation of roxadustat treatment of chronic kidney diseases
The incidence of chronic kidney disease (CKD) is increasing globally; however, effective preventive and therapeutic strategies are currently limited. Roxadustat is being clinically used to treat…
pubs.rsc.org
July 2, 2025 at 8:02 AM
Molecular Omics has a new home: we are pleased to announce the journal will be moving from the Royal Society of Chemistry journals portfolio to @oxfordunipress.bsky.social.

Find out more⬇️
bit.ly/3G3URoK
June 20, 2025 at 10:54 AM
🔓Take a look at this #OpenAccess paper by our Editorial Board member Rosario Domingues & co in our latest issue unmasking how carbamazepine induces alterations in Leydig cell lipidome #lipidomics

📍University of Aveiro, @ucoimbra.bsky.social
pubs.rsc.org/en/content/a...
Unmasking the lipid landscape: carbamazepine induces alterations in Leydig cell lipidome
Leydig cells rely on lipids and fatty acids (FA) for essential functions like maintaining structural integrity, energy metabolism, and steroid hormone synthesis, including testosterone production.…
pubs.rsc.org
June 11, 2025 at 12:08 PM
Read research in our latest issue by Jothi Basu Muthuramalingam, Jui-Yu Chou et al. at National Changhua University of Education & Alagappa University unravelling phenotypic & metabolic response of Brassica juncea induced by urea-encapsulated hydrogel beads

See it here👇
pubs.rsc.org/en/content/a...
Unraveling the phenotypic and metabolic responses induced by urea-encapsulated hydrogel beads on Brassica juncea (L.) Czern & Coss
Hydrogels, three-dimensional polymeric networks capable of absorbing and retaining significant amounts of aqueous solution, offer a promising platform for controlled release of desired compounds. In…
pubs.rsc.org
June 4, 2025 at 8:03 AM
Reposted by Molecular Omics
We are delighted to announce that Professor Christopher Chang @christhechang.bsky.social has won the 2025 Chemical Science Lectureship! rsc.li/chemsci-lectu...

Chris will deliver his Lectureship at the 2025 #ChemSciSymposium on 18-19 November in London, UK: rsc.li/chemscisymp2025

#ChemSky #🧪
May 29, 2025 at 3:14 PM
🔓Don't miss this #OpenAccess review in our latest issue by Jennifer Geddes-McAlister & co @uofguelph.bsky.social‬ highlighting dynamic and innovative applications of proteomics in fungal disease

Check it out in full on our website🔽
pubs.rsc.org/en/content/a...
Revealing the dynamics of fungal disease with proteomics
The occurrence and distribution of new and re-emerging fungal pathogens, along with rates of antifungal resistance, are rising across the globe, and correspondingly, so are our awareness and call for…
pubs.rsc.org
May 28, 2025 at 2:30 PM
📢Our latest issue is now online!

Check out the paper behind the front cover by Ana B. Castro-Ceseña & co from CICESE highlighting the enhanced anti-inflammatory and anti-fibrotic effects of nanoparticles loaded with a combination of Aloe vera–Moringa oleifera extracts

pubs.rsc.org/en/content/a...
May 19, 2025 at 2:10 PM
Don't miss this article by T. S. Keshava Prasad, Shobha Dagamajalu et al. at Yenepoya University in our latest issue revealing anticancer mechanisms of Bhallataka taila in inhibiting lung cancer progression and metastasis by proteomic analysis #omics

Check it out below👇
Proteomic analysis reveals anticancer mechanisms of Bhallataka taila in inhibiting lung cancer progression and metastasis
Lung cancer remains the leading cause of cancer-related deaths worldwide due to its poor prognosis. Despite significant advancements in the understanding of cancer development, improvements in…
pubs.rsc.org
May 7, 2025 at 8:16 AM