Mike Waring
@mikewaring.bsky.social
Professor of Medicinal Chemistry at Newcastle University and Cancer Research Horizons, Director of MoSMed CDT and Editor-in-Chief of RSC Medicinal Chemistry
New paper: We've always used TPGS in our micellar #DEL synthesis. This paper shows you can find better ones using @baonguyengroup.bsky.social surfactant map. Great work from Jake Odger et al pubs.rsc.org/en/Content/A...
Improvements in micelle promoted DNA-encoded library synthesis by surfactant optimisation
DNA-encoded libraries are increasingly important in hit identification at the early stage of the drug discovery process. The approach relies on efficient methods for synthesis of drug-like compounds a...
pubs.rsc.org
June 13, 2025 at 12:40 PM
New paper: We've always used TPGS in our micellar #DEL synthesis. This paper shows you can find better ones using @baonguyengroup.bsky.social surfactant map. Great work from Jake Odger et al pubs.rsc.org/en/Content/A...
Something makes me think that this invite might have been autogenerated...
June 9, 2025 at 12:23 PM
Something makes me think that this invite might have been autogenerated...
Reposted by Mike Waring
It's official, our med chem Senior Research Associate @hannahstewart92.bsky.social is the world's fastest scientist @guinnessworldrecords.com guinnessworldrecords.com/world-record...
May 13, 2025 at 1:20 PM
It's official, our med chem Senior Research Associate @hannahstewart92.bsky.social is the world's fastest scientist @guinnessworldrecords.com guinnessworldrecords.com/world-record...
Starting the @mosmedcdt.bsky.social conference. It will get better from here!
Great start to the @mosmedcdt.bsky.social CDT conference in Durham from director @mikewaring.bsky.social. Welcome to all the students, supervisors & industry partners in attendance!
April 15, 2025 at 9:20 AM
Starting the @mosmedcdt.bsky.social conference. It will get better from here!
Group trip to the pub / watch the bins being emptied.
April 11, 2025 at 6:05 PM
Group trip to the pub / watch the bins being emptied.
New paper published today describing some SAR on EGFR inhibitors including an interesting effect of a pair of enantiomers on covalent biinding www.nature.com/articles/s42...
Factors affecting irreversible inhibition of EGFR and influence of chirality on covalent binding - Communications Chemistry
Covalent inhibitors are a successful class of drugs, however, the optimization of targeted covalent inhibitors has challenges due to the need to increase non-covalent interactions and modulate reactiv...
www.nature.com
April 10, 2025 at 8:44 PM
New paper published today describing some SAR on EGFR inhibitors including an interesting effect of a pair of enantiomers on covalent biinding www.nature.com/articles/s42...
Reposted by Mike Waring
Prof. Mike Waring (@mikewaring.bsky.social), Chair of Medicinal Chemistry, Newcastle University #facesofscience #chemsky #sciencesky
April 7, 2025 at 12:13 PM
Prof. Mike Waring (@mikewaring.bsky.social), Chair of Medicinal Chemistry, Newcastle University #facesofscience #chemsky #sciencesky
Reposted by Mike Waring
Nikol Zografou Barredo, PhD Student (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky
April 2, 2025 at 8:34 AM
Nikol Zografou Barredo, PhD Student (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky
Reposted by Mike Waring
Dr Hannah Stewart (@hannahstewart92.bsky.social), Senior Research Associate (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky
March 31, 2025 at 10:32 AM
Dr Hannah Stewart (@hannahstewart92.bsky.social), Senior Research Associate (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky
Reposted by Mike Waring
Dr Harriet Stanway-Gordon (@harrietsg.bsky.social), Research Fellow (Medicinal Chemistry/Chemical Biology), Newcastle University #facesofscience #chemsky #sciencesky
March 17, 2025 at 9:01 AM
Dr Harriet Stanway-Gordon (@harrietsg.bsky.social), Research Fellow (Medicinal Chemistry/Chemical Biology), Newcastle University #facesofscience #chemsky #sciencesky
Highlighting scientists and the possibility that they may also be humans, give them a follow bsky.app/profile/face...
bsky.app
March 14, 2025 at 12:04 PM
Highlighting scientists and the possibility that they may also be humans, give them a follow bsky.app/profile/face...
Reposted by Mike Waring
COMING SOON! Sneak preview of the selection of people we're showcasing this month 🧪
March 3, 2025 at 3:24 PM
COMING SOON! Sneak preview of the selection of people we're showcasing this month 🧪
Reposted by Mike Waring
Dr Celine Cano, Reader in Medicinal Chemistry, Newcastle University #facesofscience #chemsky #sciencesky
March 5, 2025 at 6:07 PM
Dr Celine Cano, Reader in Medicinal Chemistry, Newcastle University #facesofscience #chemsky #sciencesky
Reposted by Mike Waring
Dr Grace Roper, PDRA (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky
March 10, 2025 at 9:28 AM
Dr Grace Roper, PDRA (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky
Reposted by Mike Waring
Dr Suzannah Harnor (@sjharnor.bsky.social), Senior Research Associate (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky
March 12, 2025 at 3:18 PM
Dr Suzannah Harnor (@sjharnor.bsky.social), Senior Research Associate (Medicinal Chemistry), Newcastle University #facesofscience #chemsky #sciencesky
We have a PhD studentship in the @nudrugdiscovery.bsky.social @chemistryncl.bsky.social with me and @hannahstewart92.bsky.social to develop methods of making macrocycles as a new class of antimicrobial agents. Apply at the link and contact us if you have questions. www.findaphd.com/phds/project...
A Build-couple-transform approach to diverse macrocyclic libraries for antimicrobial drug discovery. at Newcastle University on FindAPhD.com
PhD Project - A Build-couple-transform approach to diverse macrocyclic libraries for antimicrobial drug discovery. at Newcastle University, listed on FindAPhD.com
www.findaphd.com
March 10, 2025 at 3:48 PM
We have a PhD studentship in the @nudrugdiscovery.bsky.social @chemistryncl.bsky.social with me and @hannahstewart92.bsky.social to develop methods of making macrocycles as a new class of antimicrobial agents. Apply at the link and contact us if you have questions. www.findaphd.com/phds/project...
Check out RSC Medicinal Chemistry now on Bluesky @rscmedchem.rsc.org
bsky.app
March 6, 2025 at 2:43 AM
Check out RSC Medicinal Chemistry now on Bluesky @rscmedchem.rsc.org
Yesterday Julian Knight officially retired from @chemistryncl.bsky.social Julian is a brilliant organic chemistry lecturer and will be sorely missed
February 22, 2025 at 12:41 PM
Yesterday Julian Knight officially retired from @chemistryncl.bsky.social Julian is a brilliant organic chemistry lecturer and will be sorely missed
Congratulations to Dr Matt Anderson on passing his PhD viva yesterday. @chemistryncl.bsky.social @nudrugdiscovery.bsky.social
February 8, 2025 at 11:40 AM
Congratulations to Dr Matt Anderson on passing his PhD viva yesterday. @chemistryncl.bsky.social @nudrugdiscovery.bsky.social
We have a #PhDstudentship starting in Sept with me and @hannahstewart92.bsky.social ideal for candidates with interest in research in #medicinalchemistry and #organicsynthesis
Contact us for more details but apply through the university portal, details in the link: www.ncl.ac.uk/postgraduate...
Contact us for more details but apply through the university portal, details in the link: www.ncl.ac.uk/postgraduate...
January 31, 2025 at 6:17 PM
We have a #PhDstudentship starting in Sept with me and @hannahstewart92.bsky.social ideal for candidates with interest in research in #medicinalchemistry and #organicsynthesis
Contact us for more details but apply through the university portal, details in the link: www.ncl.ac.uk/postgraduate...
Contact us for more details but apply through the university portal, details in the link: www.ncl.ac.uk/postgraduate...
Reposted by Mike Waring
Read about our potential breakthrough in oncology - restoring wild type p53 function with ASTX295. This molecule was co-developed with Astex Pharmaceuticals, and is currently showing great phase I trial readout! #cancer #medchem #clinicaltrials
www.linkedin.com/posts/cancer...
www.linkedin.com/posts/cancer...
Cancer Research Horizons on LinkedIn: #onmyhorizon #cancerresearch
2024 milestones worth celebrating 🧬🌟
Bravo to the incredible researchers at the Drug Discovery Unit at Newcastle University. They've unlocked a potential…
www.linkedin.com
December 27, 2024 at 6:50 PM
Read about our potential breakthrough in oncology - restoring wild type p53 function with ASTX295. This molecule was co-developed with Astex Pharmaceuticals, and is currently showing great phase I trial readout! #cancer #medchem #clinicaltrials
www.linkedin.com/posts/cancer...
www.linkedin.com/posts/cancer...
Reposted by Mike Waring
Our research is critically dependent on funding we receive from @cancerresearchuk.org and we are also willing to do our bit towards fundraising. In 2024:
Funds Raised: £6,440 (+£1,031 gift aid)
Online Donations: 283
Events: Great North Run, Race for Life, Shine Walk, Leeds Marathon, bake sale, quiz
Funds Raised: £6,440 (+£1,031 gift aid)
Online Donations: 283
Events: Great North Run, Race for Life, Shine Walk, Leeds Marathon, bake sale, quiz
December 19, 2024 at 2:36 PM
Our research is critically dependent on funding we receive from @cancerresearchuk.org and we are also willing to do our bit towards fundraising. In 2024:
Funds Raised: £6,440 (+£1,031 gift aid)
Online Donations: 283
Events: Great North Run, Race for Life, Shine Walk, Leeds Marathon, bake sale, quiz
Funds Raised: £6,440 (+£1,031 gift aid)
Online Donations: 283
Events: Great North Run, Race for Life, Shine Walk, Leeds Marathon, bake sale, quiz
Reposted by Mike Waring
Exciting collaboration from our @nudrugdiscovery.bsky.social team
@newcastleuni.bsky.social, @crhorizons.bsky.social and @diamondlightsource.bsky.social to accelerate hit discovery with structure-based drug design. Big shout out to our structural biology team led by Jane Endicott & Martin Noble!🙌
@newcastleuni.bsky.social, @crhorizons.bsky.social and @diamondlightsource.bsky.social to accelerate hit discovery with structure-based drug design. Big shout out to our structural biology team led by Jane Endicott & Martin Noble!🙌
Thrilled to share the new collaboration between @diamondlightsource.bsky.social + @crhorizons.bsky.social + @newcastleuni.bsky.social to accelerate structure-based drug development via fragment screening! More here: bit.ly/4g7Et3f 🧬🧶 #chemsky #chembio We're already hard at work on exciting targets 💪
Cancer Research Horizons and Diamond Light Source establish drug discovery partnership
Cancer Research Horizons is partnering with Diamond Light Source, the UK’s national synchrotron, to build a world-leading fragment-based drug discovery programme.
bit.ly
December 13, 2024 at 9:10 AM
Exciting collaboration from our @nudrugdiscovery.bsky.social team
@newcastleuni.bsky.social, @crhorizons.bsky.social and @diamondlightsource.bsky.social to accelerate hit discovery with structure-based drug design. Big shout out to our structural biology team led by Jane Endicott & Martin Noble!🙌
@newcastleuni.bsky.social, @crhorizons.bsky.social and @diamondlightsource.bsky.social to accelerate hit discovery with structure-based drug design. Big shout out to our structural biology team led by Jane Endicott & Martin Noble!🙌
Looking forward to speaking at the #scireviewmeeting next week. Some interesting topics...
30th SCI Annual Review Meeting – New Directions in Organic Chemistry
The 30th Annual Review Meeting – New Directions in Organic Chemistry, organised by SCI's Young Chemists’ Panel, will address key areas of contemporary synthetic organic chemistry.
www.soci.org
November 29, 2024 at 6:16 PM
Looking forward to speaking at the #scireviewmeeting next week. Some interesting topics...
Reposted by Mike Waring
@utejungwirth.bsky.social and Kleopatra Papa spoke at this week's BACR New Developments in #BreastCancer Research conference, highlighting their work on the effect of chemotherapy on cancer associated fibroblasts and drug resistance 🧫 @nucancer.bsky.social @crhorizons.bsky.social #cancer #cansky
November 27, 2024 at 11:30 PM
@utejungwirth.bsky.social and Kleopatra Papa spoke at this week's BACR New Developments in #BreastCancer Research conference, highlighting their work on the effect of chemotherapy on cancer associated fibroblasts and drug resistance 🧫 @nucancer.bsky.social @crhorizons.bsky.social #cancer #cansky