Migraine Science Collaborative (MSC)
@migrainecollab.bsky.social
The MSC (https://migrainecollaborative.org) is a non-profit news website and information resource hub for the global community of migraine and headache researchers, clinicians, and others interested in learning more about the science.
Pinned
Exercise to Improve Migraine: How Much Is Enough? - Migraine Science Collaborative
A new meta-analysis posits an aerobic exercise therapeutic window for reducing migraine pain and frequency, though uncertainty remains.
migrainecollaborative.org
MSC News: A new meta-analysis posits an aerobic exercise therapeutic window for reducing #migraine pain and frequency, though uncertainty remains. Nice work by @fredakreier.bsky.social
migrainecollaborative.org/exercise-to-...
migrainecollaborative.org/exercise-to-...
The latest MSC literature recap is now live! Take a look at the newest papers that made it onto our list this time around. #migraine #headache #pain
migrainecollaborative.org/paper-date/2...
migrainecollaborative.org/paper-date/2...
January 30, 2026 at 3:24 PM
The latest MSC literature recap is now live! Take a look at the newest papers that made it onto our list this time around. #migraine #headache #pain
migrainecollaborative.org/paper-date/2...
migrainecollaborative.org/paper-date/2...
Our latest update on clinical studies in the #migraine field is now live. Highlights include successful phase 4 trials, new studies on #psychedelics, migraine in men, and more.
migrainecollaborative.org/january-2026...
migrainecollaborative.org/january-2026...
January 2026 Clinical Research Update: The Latest Findings in Migraine - Migraine Science Collaborative
Highlights include successful phase 4 trials, new studies on psychedelics, migraine in men, and more.
migrainecollaborative.org
January 28, 2026 at 2:59 PM
Our latest update on clinical studies in the #migraine field is now live. Highlights include successful phase 4 trials, new studies on #psychedelics, migraine in men, and more.
migrainecollaborative.org/january-2026...
migrainecollaborative.org/january-2026...
In case you missed it: A recent MSC news story described what the future looks like for HEAL, one of the most visible and important governmental efforts to support #pain -- and #migraine -- research in the United States. Take a look:
migrainecollaborative.org/reason-for-o...
migrainecollaborative.org/reason-for-o...
Reason for Optimism: The HEAL Initiative Prepares for the Future - Migraine Science Collaborative
The publication of a roadmap for HEAL research earlier this year sets the stage for 2026 and beyond.
migrainecollaborative.org
January 27, 2026 at 3:59 PM
In case you missed it: A recent MSC news story described what the future looks like for HEAL, one of the most visible and important governmental efforts to support #pain -- and #migraine -- research in the United States. Take a look:
migrainecollaborative.org/reason-for-o...
migrainecollaborative.org/reason-for-o...
What's the best "dose" of #exercise to improve #migraine? That's the focus of our latest news story, which covers a recent meta-analysis that posits an aerobic exercise therapeutic window for reducing migraine #pain and frequency, though uncertainty remains.
migrainecollaborative.org/exercise-to-...
migrainecollaborative.org/exercise-to-...
Exercise to Improve Migraine: How Much Is Enough? - Migraine Science Collaborative
A new meta-analysis posits an aerobic exercise therapeutic window for reducing migraine pain and frequency, though uncertainty remains.
migrainecollaborative.org
January 23, 2026 at 3:34 PM
What's the best "dose" of #exercise to improve #migraine? That's the focus of our latest news story, which covers a recent meta-analysis that posits an aerobic exercise therapeutic window for reducing migraine #pain and frequency, though uncertainty remains.
migrainecollaborative.org/exercise-to-...
migrainecollaborative.org/exercise-to-...
In case you missed it: A new scoping review describes knowledge generated from more than 50 years of research about social disparities in #pain. #migraine #headache
migrainecollaborative.org/the-big-pict...
migrainecollaborative.org/the-big-pict...
The Big Picture: What We Know – and Don’t Know – about Social Disparities in Pain Treatment and Outcomes - Migraine Science Collaborative
A new scoping review describes knowledge generated from more than 50 years of research.
migrainecollaborative.org
January 21, 2026 at 5:18 PM
In case you missed it: A new scoping review describes knowledge generated from more than 50 years of research about social disparities in #pain. #migraine #headache
migrainecollaborative.org/the-big-pict...
migrainecollaborative.org/the-big-pict...
MSC News: A new meta-analysis posits an aerobic exercise therapeutic window for reducing #migraine pain and frequency, though uncertainty remains. Nice work by @fredakreier.bsky.social
migrainecollaborative.org/exercise-to-...
migrainecollaborative.org/exercise-to-...
Exercise to Improve Migraine: How Much Is Enough? - Migraine Science Collaborative
A new meta-analysis posits an aerobic exercise therapeutic window for reducing migraine pain and frequency, though uncertainty remains.
migrainecollaborative.org
January 20, 2026 at 5:12 PM
MSC News: A new meta-analysis posits an aerobic exercise therapeutic window for reducing #migraine pain and frequency, though uncertainty remains. Nice work by @fredakreier.bsky.social
migrainecollaborative.org/exercise-to-...
migrainecollaborative.org/exercise-to-...
Our latest literature recap is now live! Take a look at the research papers -- basic science, translational, and clinical studies -- that made it into this popular biweekly feature of MSC this time around.
migrainecollaborative.org/paper-date/2...
migrainecollaborative.org/paper-date/2...
January 16, 2026 at 5:55 PM
Our latest literature recap is now live! Take a look at the research papers -- basic science, translational, and clinical studies -- that made it into this popular biweekly feature of MSC this time around.
migrainecollaborative.org/paper-date/2...
migrainecollaborative.org/paper-date/2...
In case you missed it, take a look at our interview with #migraine researcher Philip Holland, who chatted with MSC about his path to the migraine field, some of the projects he’s working on now, and his interests outside of science.
migrainecollaborative.org/understandin...
migrainecollaborative.org/understandin...
Understanding the Pathophysiology of Headache Disorders: An Interview with Philip Holland - Migraine Science Collaborative
Philip Holland discusses his path to the migraine field, some of the projects he’s working on now, and his interests outside of science.
migrainecollaborative.org
January 14, 2026 at 4:06 PM
In case you missed it, take a look at our interview with #migraine researcher Philip Holland, who chatted with MSC about his path to the migraine field, some of the projects he’s working on now, and his interests outside of science.
migrainecollaborative.org/understandin...
migrainecollaborative.org/understandin...
The latest MSC e-Newsletter is now live! Take a look at what we've been up to over the past month -- all the #migraine and #headache research that we've covered.
conta.cc/4sBnQnl
conta.cc/4sBnQnl
January 13, 2026 at 3:26 PM
The latest MSC e-Newsletter is now live! Take a look at what we've been up to over the past month -- all the #migraine and #headache research that we've covered.
conta.cc/4sBnQnl
conta.cc/4sBnQnl
Take a look at our latest interview! We talk with MSC editorial board member Phil Holland, who talks about his work on the pathophysiological mechanisms of #migraine, including studies on the premonitory symptoms of the condition.
migrainecollaborative.org/understandin...
migrainecollaborative.org/understandin...
Understanding the Pathophysiology of Headache Disorders: An Interview with Philip Holland - Migraine Science Collaborative
Philip Holland discusses his path to the migraine field, some of the projects he’s working on now, and his interests outside of science.
migrainecollaborative.org
January 9, 2026 at 1:12 PM
Take a look at our latest interview! We talk with MSC editorial board member Phil Holland, who talks about his work on the pathophysiological mechanisms of #migraine, including studies on the premonitory symptoms of the condition.
migrainecollaborative.org/understandin...
migrainecollaborative.org/understandin...
Join us for tonight's MSC 5th Annual Emerging Science Contest for Early-Career Investigators! Up-and-coming grad students and postdocs will present their work on an intriguing range of basic science and clinical topics in #migraine and related fields. Register here:
us02web.zoom.us/meeting/regi...
us02web.zoom.us/meeting/regi...
January 7, 2026 at 4:05 PM
Join us for tonight's MSC 5th Annual Emerging Science Contest for Early-Career Investigators! Up-and-coming grad students and postdocs will present their work on an intriguing range of basic science and clinical topics in #migraine and related fields. Register here:
us02web.zoom.us/meeting/regi...
us02web.zoom.us/meeting/regi...
MSC News: A new scoping review describes knowledge generated from more than 50 years of #pain research on social #disparities.
migrainecollaborative.org/the-big-pict...
migrainecollaborative.org/the-big-pict...
The Big Picture: What We Know – and Don’t Know – about Social Disparities in Pain Treatment and Outcomes - Migraine Science Collaborative
A new scoping review describes knowledge generated from more than 50 years of research.
migrainecollaborative.org
January 5, 2026 at 7:40 PM
MSC News: A new scoping review describes knowledge generated from more than 50 years of #pain research on social #disparities.
migrainecollaborative.org/the-big-pict...
migrainecollaborative.org/the-big-pict...
The final MSC biweekly literature recap of 2025 is now live! Take a look at all the #migraine and #headache research captured in our newest crop of papers -- three editor's picks included.
migrainecollaborative.org/paper-date/2...
migrainecollaborative.org/paper-date/2...
December 31, 2025 at 3:38 PM
The final MSC biweekly literature recap of 2025 is now live! Take a look at all the #migraine and #headache research captured in our newest crop of papers -- three editor's picks included.
migrainecollaborative.org/paper-date/2...
migrainecollaborative.org/paper-date/2...
We've finally reached #1 in our countdown of the most popular content on MSC in 2025! Taking the top spot is our coverage of a study finding that a 100:1 ratio of CBD to THC effectively reduced migraine-like symptoms in three preclinical models.
migrainecollaborative.org/cbd-and-thc-...
migrainecollaborative.org/cbd-and-thc-...
CBD and THC for Migraine Treatment: A Study in Mice Says Working Together Is Better Than Working Alone - Migraine Science Collaborative
New research finds that a 100:1 ratio of CBD to THC effectively reduces migraine-like symptoms in three preclinical models of migraine. The results could help clinical investigators as they test the d...
migrainecollaborative.org
December 29, 2025 at 6:31 PM
We've finally reached #1 in our countdown of the most popular content on MSC in 2025! Taking the top spot is our coverage of a study finding that a 100:1 ratio of CBD to THC effectively reduced migraine-like symptoms in three preclinical models.
migrainecollaborative.org/cbd-and-thc-...
migrainecollaborative.org/cbd-and-thc-...
The countdown continues: The second most popular article on MSC this year covered a study showing that a key #migraine mechanism -- #CGRP signaling -- also plays a role in #pain resulting from endometriosis. Take a look on MSC today.
migrainecollaborative.org/a-key-migrai...
migrainecollaborative.org/a-key-migrai...
A Key Migraine Mechanism Is Responsible for Endometriosis Pain - Migraine Science Collaborative
CGRP signaling from neurons to immune cells drives endometriosis pain and lesion growth, suggesting that CGRP-blocking drugs could be a potential treatment for the condition.
migrainecollaborative.org
December 26, 2025 at 3:44 PM
The countdown continues: The second most popular article on MSC this year covered a study showing that a key #migraine mechanism -- #CGRP signaling -- also plays a role in #pain resulting from endometriosis. Take a look on MSC today.
migrainecollaborative.org/a-key-migrai...
migrainecollaborative.org/a-key-migrai...
We're counting them down: The third most popular article on MSC this year was our story on new governmental science policies and their potential effects on the #migraine field. The migraine community was uncertain about how the new directives will play out.
migrainecollaborative.org/new-us-gover...
migrainecollaborative.org/new-us-gover...
New US Government Policies Hit the Migraine Field - Migraine Science Collaborative
Members of the migraine community express uncertainty about how the new directives will play out.
migrainecollaborative.org
December 23, 2025 at 4:14 PM
We're counting them down: The third most popular article on MSC this year was our story on new governmental science policies and their potential effects on the #migraine field. The migraine community was uncertain about how the new directives will play out.
migrainecollaborative.org/new-us-gover...
migrainecollaborative.org/new-us-gover...
Check out the latest edition of the MSC biweekly literature recap. Lots of interesting research in #migraine and #headache to consider.
migrainecollaborative.org/paper-date/2...
migrainecollaborative.org/paper-date/2...
December 18, 2025 at 4:07 PM
Check out the latest edition of the MSC biweekly literature recap. Lots of interesting research in #migraine and #headache to consider.
migrainecollaborative.org/paper-date/2...
migrainecollaborative.org/paper-date/2...
MSC News: The publication of a roadmap for HEAL research earlier this year sets the stage for 2026 and beyond. #painresearch #migraineresearch #headacheresearch
migrainecollaborative.org/reason-for-o...
migrainecollaborative.org/reason-for-o...
Reason for Optimism: The HEAL Initiative Prepares for the Future - Migraine Science Collaborative
The publication of a roadmap for HEAL research earlier this year sets the stage for 2026 and beyond.
migrainecollaborative.org
December 18, 2025 at 4:03 PM
MSC News: The publication of a roadmap for HEAL research earlier this year sets the stage for 2026 and beyond. #painresearch #migraineresearch #headacheresearch
migrainecollaborative.org/reason-for-o...
migrainecollaborative.org/reason-for-o...
The fourth most popular article on MSC in 2025: Our coverage of a new study that combined structural MRI, functional MRI, and PET imaging to connect changes in the trigeminal root entry zone to inflammation and brainstem activity in people with #migraine.
migrainecollaborative.org/the-trigemin...
migrainecollaborative.org/the-trigemin...
The Trigeminal Nerve and Migraine: Linking Structure to Function - Migraine Science Collaborative
A new study combines structural MRI, functional MRI, and PET imaging to connect changes in the trigeminal root entry zone to inflammation and brainstem activity in people with migraine.
migrainecollaborative.org
December 17, 2025 at 5:35 PM
The fourth most popular article on MSC in 2025: Our coverage of a new study that combined structural MRI, functional MRI, and PET imaging to connect changes in the trigeminal root entry zone to inflammation and brainstem activity in people with #migraine.
migrainecollaborative.org/the-trigemin...
migrainecollaborative.org/the-trigemin...
Our countdown continues: Our 5th most popular article this year covered an animal study, supported by human data, showing that cellular senescence is associated with neuropathic and facial #pain. A similar process could also underlie #headache conditions.
migrainecollaborative.org/when-cells-a...
migrainecollaborative.org/when-cells-a...
When Cells Age: A New Contributor to Chronic Pain – and Potentially to Headache, Too - Migraine Science Collaborative
An animal study, supported by human data, shows that cellular senescence is associated with neuropathic and facial pain. The findings suggest that a similar process could also underlie headache condit...
migrainecollaborative.org
December 16, 2025 at 4:35 PM
Our countdown continues: Our 5th most popular article this year covered an animal study, supported by human data, showing that cellular senescence is associated with neuropathic and facial #pain. A similar process could also underlie #headache conditions.
migrainecollaborative.org/when-cells-a...
migrainecollaborative.org/when-cells-a...
We're counting down the most popular content on MSC in 2025! Coming in at #7 is our coverage of a longitudinal study of a rare type of #migraine suggesting that every attack of this rare condition should be treated as potentially life threatening.
migrainecollaborative.org/taking-the-l...
migrainecollaborative.org/taking-the-l...
Taking the Long View to Understand CACNA1A-Related Hemiplegic Migraine - Migraine Science Collaborative
A new longitudinal study of a rare type of migraine suggests every attack should be treated as potentially life threatening.
migrainecollaborative.org
December 15, 2025 at 5:57 PM
We're counting down the most popular content on MSC in 2025! Coming in at #7 is our coverage of a longitudinal study of a rare type of #migraine suggesting that every attack of this rare condition should be treated as potentially life threatening.
migrainecollaborative.org/taking-the-l...
migrainecollaborative.org/taking-the-l...
We're counting down the most popular articles on MSC published over the past year. Coming in at number 9: Our interview with vestibular #migraine (VM) expert Dr. Hamid R. Djalilian. VM a condition that is mis- and under-diagnosed -- read why on MSC today.
migrainecollaborative.org/bringing-att...
migrainecollaborative.org/bringing-att...
Bringing Attention to Vestibular Migraine: A Conversation with Hamid Djalilian - Migraine Science Collaborative
In this Migraine Science Collaborative interview, Dr. Hamid Djalilian discusses his interest in vestibular migraine, the mis- and under-diagnosis of this condition, and what he would like people to kn...
migrainecollaborative.org
December 12, 2025 at 3:30 PM
We're counting down the most popular articles on MSC published over the past year. Coming in at number 9: Our interview with vestibular #migraine (VM) expert Dr. Hamid R. Djalilian. VM a condition that is mis- and under-diagnosed -- read why on MSC today.
migrainecollaborative.org/bringing-att...
migrainecollaborative.org/bringing-att...
We're counting down the most popular articles on MSC in 2025! At #10 is our coverage of a clinical trial showing that fremanezumab, an anti-CGRP antibody for #migraine, could also be an effective drug to manage depression, a common comorbidity of migraine.
migrainecollaborative.org/new-clinical...
migrainecollaborative.org/new-clinical...
New Clinical Trial Results: Anti-CGRP Treatment Improves Migraine and Comorbid Depression - Migraine Science Collaborative
The first study of its kind shows that fremanezumab could be an effective drug to manage this common comorbidity of migraine.
migrainecollaborative.org
December 11, 2025 at 3:35 PM
We're counting down the most popular articles on MSC in 2025! At #10 is our coverage of a clinical trial showing that fremanezumab, an anti-CGRP antibody for #migraine, could also be an effective drug to manage depression, a common comorbidity of migraine.
migrainecollaborative.org/new-clinical...
migrainecollaborative.org/new-clinical...
As the year draws to a close, it's time for our annual Top 10 list of the most popular content published on Migraine Science Collaborative during the year. Take a look!
migrainecollaborative.org/popularity-c...
migrainecollaborative.org/popularity-c...
Popularity Contest: What Were You Reading in 2025? - Migraine Science Collaborative
MSC coverage of a mouse study testing the effectiveness of different ratios of CBD to THC in reducing migraine-like symptoms takes the top spot in our annual Top 10 list.
migrainecollaborative.org
December 9, 2025 at 3:17 PM
As the year draws to a close, it's time for our annual Top 10 list of the most popular content published on Migraine Science Collaborative during the year. Take a look!
migrainecollaborative.org/popularity-c...
migrainecollaborative.org/popularity-c...
Check out the latest MSC interview! Dr. Jessica Ailani discusses her research on treating #migraine early, before a trigger occurs. She also delves into her participation in the Headache Research Priorities initiative from the American Headache Society.
migrainecollaborative.org/treating-mig...
migrainecollaborative.org/treating-mig...
Treating Migraine Early: A Conversation with Jessica Ailani - Migraine Science Collaborative
In this Migraine Science Collaborative interview, Jessica Ailani discusses her research on situational prevention of migraine, and her participation in the development of the AHS's Headache Research P...
migrainecollaborative.org
December 5, 2025 at 3:48 PM
Check out the latest MSC interview! Dr. Jessica Ailani discusses her research on treating #migraine early, before a trigger occurs. She also delves into her participation in the Headache Research Priorities initiative from the American Headache Society.
migrainecollaborative.org/treating-mig...
migrainecollaborative.org/treating-mig...