Dan Michele
@michelelabum.bsky.social
Professor and Chair
Department of Molecular & Integrative Physiology
University of Michigan Medical School
Department of Molecular & Integrative Physiology
University of Michigan Medical School
Reposted by Dan Michele
Latest from our group in collaboration with Lotte Bjerre Knudsen and other Novo scientists. They developed a GLP-1/Leptin co-agonist that we put through its paces in a number of mouse models to prove that both parts of the molecule matter. More options on the table!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Glp1r-Lepr coexpressing neurons modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist
Orthogonal murine models demonstrate the bioactivity and neuronal targets of a GLP-1/leptin coagonist in relation to food intake and body weight.
www.science.org
December 4, 2024 at 8:27 PM
Latest from our group in collaboration with Lotte Bjerre Knudsen and other Novo scientists. They developed a GLP-1/Leptin co-agonist that we put through its paces in a number of mouse models to prove that both parts of the molecule matter. More options on the table!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Pleased to have @kaesser.bsky.social visit UMPhysiology to give the annual John and Margaret Faulkner Lecture and share her work on the circadian clock in muscle. Karyn spent a little time in John's lab as a PhD student in Kinesiology so it was also a homecoming. #myoblue
December 5, 2024 at 11:11 PM
Pleased to have @kaesser.bsky.social visit UMPhysiology to give the annual John and Margaret Faulkner Lecture and share her work on the circadian clock in muscle. Karyn spent a little time in John's lab as a PhD student in Kinesiology so it was also a homecoming. #myoblue