Michelangelo Certo
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mic-certo.bsky.social
Michelangelo Certo
@mic-certo.bsky.social
Pharmacologist - Immunometabolism in Atherosclerosis and Stroke @unibirm_MDS #Atherosclerosis #Stroke #Inflammation Science illustrator. Italobritish
I found this review extremely informative and highly recommend reading it! It provides a comprehensive overview of energy metabolism, its role in health and disease, and emerging therapeutic strategies. #metabolism

www.nature.com/articles/s41...
Energy metabolism in health and diseases - Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy - Energy metabolism in health and diseases
www.nature.com
March 12, 2025 at 10:48 PM
Great question! Regular physical activity is indeed linked to improved immune responses, but lactate’s role is more nuanced. Moderate exercise generally supports immune function, while excessive exertion can sometimes lead to temporary suppression.
March 12, 2025 at 10:25 PM
Our latest review is out in Immunity! Lactate is now recognized as a key immune regulator. It shapes gene expression, signals immune cells, and impacts diseases like cancer & autoimmunity. Could lactate be a new therapeutic target? Read more! 🧬💊
www.cell.com/immunity/ful... @cp-immunity.bsky.social
Lactate: A key regulator of the immune response
Lactate shows immunomodulatory properties. Mauro et al. review how lactate serves a fuel for the TCA cycle and an immunomodulatory molecule with context-dependent effects, and how its immunomodulatory...
www.cell.com
March 12, 2025 at 3:21 PM