Maximilian Hoffmann
@mh123.bsky.social
This is the worst I'll ever be
Reposted by Maximilian Hoffmann
The saxophonist, flutist, and composer has transformed the music over and over with Air, the Sextett, Very Very Circus, Zooid, and more. https://bit.ly/4mMB50X
Henry Threadgill turns jazz into a kaleidoscope of worlds and times - Chicago Reader
Saxophonist, flutist, and composer Henry Threadgill has transformed the music over and over with Air, the Sextett, Very Very Circus, Zooid, and more.
bit.ly
September 5, 2025 at 8:55 PM
The saxophonist, flutist, and composer has transformed the music over and over with Air, the Sextett, Very Very Circus, Zooid, and more. https://bit.ly/4mMB50X
Reposted by Maximilian Hoffmann
🧬🔬🧪 🎉 Our team at @czbiohub is thrilled to share TWO companion papers out today in @NatureMethods!
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 25, 2025 at 9:06 AM
🧬🔬🧪 🎉 Our team at @czbiohub is thrilled to share TWO companion papers out today in @NatureMethods!
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Maximilian Hoffmann
Reposted by Maximilian Hoffmann
Interesting scheme for categorizing sensory systems- from Ching Kung, motivated by exploring sensory needs beginning with single-cell organisms.
July 24, 2025 at 12:37 AM
Interesting scheme for categorizing sensory systems- from Ching Kung, motivated by exploring sensory needs beginning with single-cell organisms.
Reposted by Maximilian Hoffmann
Model organism communities are fantastic. Good work, "Drosophilists"! www.nature.com/articles/d41...
Giant study finds a research field that’s mostly reproducible
Researchers assessed more than 1,000 results from fruit-fly immunity research published between 1959 and 2011. The majority of findings look verifiable.
www.nature.com
July 16, 2025 at 5:55 PM
Model organism communities are fantastic. Good work, "Drosophilists"! www.nature.com/articles/d41...
Reposted by Maximilian Hoffmann
Is it true you use only 10 bits / s of your brain?
@andpru.bsky.social and I provide a motor systems perspective on a proposed speed limit for human information processing. Out today in
@natneuro.nature.com:
www.nature.com/articles/s41...
@andpru.bsky.social and I provide a motor systems perspective on a proposed speed limit for human information processing. Out today in
@natneuro.nature.com:
www.nature.com/articles/s41...
sky.social
June 13, 2025 at 12:46 PM
Is it true you use only 10 bits / s of your brain?
@andpru.bsky.social and I provide a motor systems perspective on a proposed speed limit for human information processing. Out today in
@natneuro.nature.com:
www.nature.com/articles/s41...
@andpru.bsky.social and I provide a motor systems perspective on a proposed speed limit for human information processing. Out today in
@natneuro.nature.com:
www.nature.com/articles/s41...
Reposted by Maximilian Hoffmann
Why human connectomes can probably not be useful for AI
open.substack.com/pub/kording/...
open.substack.com/pub/kording/...
Lions and Dolphins can not make babies: Why human connectomes can probably not be useful for AI
How evolutionary thinking can make the debate more precise
open.substack.com
June 4, 2025 at 12:52 PM
Why human connectomes can probably not be useful for AI
open.substack.com/pub/kording/...
open.substack.com/pub/kording/...
Reposted by Maximilian Hoffmann
Behind the Scenes: Brad Mehldau Records “Tomorrow Tomorrow” (feat. Daniel Rossen) #blogpost
Behind the Scenes: Brad Mehldau Records “Tomorrow Tomorrow” (feat. Daniel Rossen)
A behind-the-scenes look as Brad Mehldau records Elliott Smith's "Tomorrow Tomorrow," feat. Daniel Rossen, from his upcoming album, 'Ride into the Sun,' due August 29 on Nonesuch Records. Pre-order: bradmehldau.lnk.to Brad Mehldau – Piano
Daniel Rossen – Lead Vocals, Acoustic Guitar Chris Thile – Mandolin, Backing Vocals Felix Moseholm – Acoustic Bass Matt Chamberlain – Drums Video by Matthew Edginton. Filmed at The Bunker Studio in Brooklyn, NY. #BradMehldau #ElliottSmith #BehindTheScenes
littlegreenfootballs.com
June 2, 2025 at 10:52 PM
Behind the Scenes: Brad Mehldau Records “Tomorrow Tomorrow” (feat. Daniel Rossen) #blogpost
Reposted by Maximilian Hoffmann
Introducing warpfield, an open source Python library for GPU-accelerated non-rigid 3D registration. Warps and aligns gigavoxel volumes within seconds (not hours). For 3D microscopy, region-to-region and cell-to-cell matching.
A collaboration with @mh123.bsky.social 🚀
github.com/danionella/w...
A collaboration with @mh123.bsky.social 🚀
github.com/danionella/w...
May 12, 2025 at 5:25 AM
Introducing warpfield, an open source Python library for GPU-accelerated non-rigid 3D registration. Warps and aligns gigavoxel volumes within seconds (not hours). For 3D microscopy, region-to-region and cell-to-cell matching.
A collaboration with @mh123.bsky.social 🚀
github.com/danionella/w...
A collaboration with @mh123.bsky.social 🚀
github.com/danionella/w...
Reposted by Maximilian Hoffmann
We made a film!
About Michael Saylor and his amazing magic money machine. Take bitcoin, add mind-boggling amounts of financial engineering and a huge dose of very online crypto hype, and suddenly a lot of people are making a LOT of money
www.youtube.com/watch?v=O_Wj...
About Michael Saylor and his amazing magic money machine. Take bitcoin, add mind-boggling amounts of financial engineering and a huge dose of very online crypto hype, and suddenly a lot of people are making a LOT of money
www.youtube.com/watch?v=O_Wj...
Michael Saylor's $40bn bitcoin bet | FT Film
YouTube video by Financial Times
www.youtube.com
May 15, 2025 at 9:46 AM
We made a film!
About Michael Saylor and his amazing magic money machine. Take bitcoin, add mind-boggling amounts of financial engineering and a huge dose of very online crypto hype, and suddenly a lot of people are making a LOT of money
www.youtube.com/watch?v=O_Wj...
About Michael Saylor and his amazing magic money machine. Take bitcoin, add mind-boggling amounts of financial engineering and a huge dose of very online crypto hype, and suddenly a lot of people are making a LOT of money
www.youtube.com/watch?v=O_Wj...
Reposted by Maximilian Hoffmann
Hot takes/kind reminders
a) “the bitter lesson”’s promise of scale did not deliver wrt AI reasoning & higher cog functions—O3 hallucinates 2x more than O1
b) prediction is not understanding, hallucinating is worse
c) gen AI could help neuroAI but following latest AI trends is not a paradigm shift
a) “the bitter lesson”’s promise of scale did not deliver wrt AI reasoning & higher cog functions—O3 hallucinates 2x more than O1
b) prediction is not understanding, hallucinating is worse
c) gen AI could help neuroAI but following latest AI trends is not a paradigm shift
How can we make progress in developing a general model of neural computation rather than a series of disjointed models tied to specific experimental circumstances, ask Eva Dyer and @tyrellturing.bsky.social in the latest entry in our NeuroAI series.
www.thetransmitter.org/neuroai/acce...
www.thetransmitter.org/neuroai/acce...
Accepting “bitter lesson” and embracing brain’s complexity
To gain insight into complex neural data, we must move toward a data-driven regime, employing large models trained on vast amounts of data. Experts weigh in.
www.thetransmitter.org
May 8, 2025 at 6:42 PM
Hot takes/kind reminders
a) “the bitter lesson”’s promise of scale did not deliver wrt AI reasoning & higher cog functions—O3 hallucinates 2x more than O1
b) prediction is not understanding, hallucinating is worse
c) gen AI could help neuroAI but following latest AI trends is not a paradigm shift
a) “the bitter lesson”’s promise of scale did not deliver wrt AI reasoning & higher cog functions—O3 hallucinates 2x more than O1
b) prediction is not understanding, hallucinating is worse
c) gen AI could help neuroAI but following latest AI trends is not a paradigm shift
Reposted by Maximilian Hoffmann
if you love the handbasket and want to keep it going strong, quote post this with why you’re a paid subscriber!
i’m 200 away from a major goal. LFG.
www.thehandbasket.co/upgrade
i’m 200 away from a major goal. LFG.
www.thehandbasket.co/upgrade
The Handbasket
100% independent journalism by Marisa Kabas
www.thehandbasket.co
April 25, 2025 at 2:40 AM
if you love the handbasket and want to keep it going strong, quote post this with why you’re a paid subscriber!
i’m 200 away from a major goal. LFG.
www.thehandbasket.co/upgrade
i’m 200 away from a major goal. LFG.
www.thehandbasket.co/upgrade
Reposted by Maximilian Hoffmann
It is hard to imagine a more prescient compilation than 1992's Artificial Intelligence, not just in terms of the careers of the contributing artists, but how the featured sounds have permeated popular culture over the last 30 years.
April 9, 2025 at 1:46 PM
It is hard to imagine a more prescient compilation than 1992's Artificial Intelligence, not just in terms of the careers of the contributing artists, but how the featured sounds have permeated popular culture over the last 30 years.
It is of course painful that all this is gone..
Gottfried Benn on Berlin
www.youtube.com/watch?v=c6R4...
Gottfried Benn on Berlin
www.youtube.com/watch?v=c6R4...
Gottfried Benn im Interview 1956
YouTube video by Leah Herz
www.youtube.com
April 4, 2025 at 8:00 PM
It is of course painful that all this is gone..
Gottfried Benn on Berlin
www.youtube.com/watch?v=c6R4...
Gottfried Benn on Berlin
www.youtube.com/watch?v=c6R4...
Reposted by Maximilian Hoffmann
“Relevant computations happen in here too”
Maimon on the limitations of pure connectivity data in the fly
Maimon on the limitations of pure connectivity data in the fly
March 30, 2025 at 7:00 PM
“Relevant computations happen in here too”
Maimon on the limitations of pure connectivity data in the fly
Maimon on the limitations of pure connectivity data in the fly
Whether foundation models are the answer or not, what should be mentioned is that scaling up neuroscience is also an ... experimental problem, not just an archival one. I think the IBL experiments are maybe the most complex experiments that have been run at scale and they are mid-level complexity.
Eva Dyer and I wrote an opinion piece for @thetransmitter.bsky.social on why neuroscience needs to embrace complexity and accept the "bitter lesson" by using a data-driven regime at scale.
With commentary from several wonderful researchers!
🧠📈 #NeuroAI 🧪
With commentary from several wonderful researchers!
🧠📈 #NeuroAI 🧪
How can we make progress in developing a general model of neural computation rather than a series of disjointed models tied to specific experimental circumstances, ask Eva Dyer and @tyrellturing.bsky.social in the latest entry in our NeuroAI series.
www.thetransmitter.org/neuroai/acce...
www.thetransmitter.org/neuroai/acce...
March 26, 2025 at 5:40 PM
Whether foundation models are the answer or not, what should be mentioned is that scaling up neuroscience is also an ... experimental problem, not just an archival one. I think the IBL experiments are maybe the most complex experiments that have been run at scale and they are mid-level complexity.
Reposted by Maximilian Hoffmann
Hey fellow Drosophila researchers - if you haven't heard, the UMGC is offering ultra low-cost genome sequencing! See here to learn more: z.umn.edu/UMGC-MOSS #Dros25
March 22, 2025 at 11:39 PM
Hey fellow Drosophila researchers - if you haven't heard, the UMGC is offering ultra low-cost genome sequencing! See here to learn more: z.umn.edu/UMGC-MOSS #Dros25
Reposted by Maximilian Hoffmann
Hello world! We are building *personalized* feeds to help you make sense of research discussions on BlueSky! Pin our first feed below, which shows posts about papers from accounts you follow! Follow this account for more updates!
bsky.app/profile/pape...
bsky.app/profile/pape...
March 10, 2025 at 3:07 PM
Hello world! We are building *personalized* feeds to help you make sense of research discussions on BlueSky! Pin our first feed below, which shows posts about papers from accounts you follow! Follow this account for more updates!
bsky.app/profile/pape...
bsky.app/profile/pape...
Reposted by Maximilian Hoffmann
if anyone happens to be a physicist thinking about this offer, drop me a DM and I will give glowing character reference for one of the profs there who did an exchange to Exeter university a few years ago and is an absolutely top lad
www.univ-amu.fr/fr/public/ac...
www.univ-amu.fr/fr/public/ac...
Safe Place For Science : Aix Marseille Université prête à accueillir les scientifiques américains | Aix Marseille Université
Dans un contexte où certains scientifiques aux États-Unis peuvent se sentir menacés ou entravés dans leurs recherches, notre université annonce mettre en place le programme Safe Place For Science dédi...
www.univ-amu.fr
March 13, 2025 at 7:33 PM
if anyone happens to be a physicist thinking about this offer, drop me a DM and I will give glowing character reference for one of the profs there who did an exchange to Exeter university a few years ago and is an absolutely top lad
www.univ-amu.fr/fr/public/ac...
www.univ-amu.fr/fr/public/ac...
Reposted by Maximilian Hoffmann
In the newest issue of Science, meself, @alisongopnik.bsky.social, Cosma Shalizi and James Evans, "Large AI Models are Cultural and Social Technologies." More soon ...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Large AI models are cultural and social technologies
Implications draw on the history of transformative information systems from the past
www.science.org
March 13, 2025 at 6:06 PM
In the newest issue of Science, meself, @alisongopnik.bsky.social, Cosma Shalizi and James Evans, "Large AI Models are Cultural and Social Technologies." More soon ...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
The horseshoe theory, but for animal and AI consciousness
March 13, 2025 at 5:56 PM
The horseshoe theory, but for animal and AI consciousness
Reposted by Maximilian Hoffmann
Thrilled and proud about our latest advancement in Brillouin microscopy - enabling true light-sheet like mechanical imaging at high throughput. Out today in @naturephotonics.bsky.social
Congratulations Carlo! @carlobevilacqua.bsky.social
rdcu.be/eaDiX
Congratulations Carlo! @carlobevilacqua.bsky.social
rdcu.be/eaDiX
Full-field Brillouin microscopy based on an imaging Fourier-transform spectrometer
Nature Photonics - A Fourier-transform imaging spectrometer enables two-dimensional spectral Brillouin imaging at a throughput of up to 40,000 spectra per second over a...
rdcu.be
February 20, 2025 at 8:00 PM
Thrilled and proud about our latest advancement in Brillouin microscopy - enabling true light-sheet like mechanical imaging at high throughput. Out today in @naturephotonics.bsky.social
Congratulations Carlo! @carlobevilacqua.bsky.social
rdcu.be/eaDiX
Congratulations Carlo! @carlobevilacqua.bsky.social
rdcu.be/eaDiX
Reposted by Maximilian Hoffmann
The youth gender divide is real and important, but it can mask the fact that the populist right is gaining ground among young women as well as young men in many countries (this was also true in the US).
AfD tripled their vote share among 18-24 year old men, but the same was true of young women.
AfD tripled their vote share among 18-24 year old men, but the same was true of young women.
February 24, 2025 at 3:48 PM
The youth gender divide is real and important, but it can mask the fact that the populist right is gaining ground among young women as well as young men in many countries (this was also true in the US).
AfD tripled their vote share among 18-24 year old men, but the same was true of young women.
AfD tripled their vote share among 18-24 year old men, but the same was true of young women.
Reposted by Maximilian Hoffmann
12. In the medium to longer term, perhaps developing some of the tools that it had begun to experiment with as an alternative to dollar payments in Trump's first term. Mutterings about the strategic value of separate European digital payments systems are likely to get a _lot_ louder.
February 23, 2025 at 10:13 PM
12. In the medium to longer term, perhaps developing some of the tools that it had begun to experiment with as an alternative to dollar payments in Trump's first term. Mutterings about the strategic value of separate European digital payments systems are likely to get a _lot_ louder.
Reposted by Maximilian Hoffmann
Aus. Vorbei. Zum ersten Mal in meinem Leben werde ich meine Stimme bei einer Bundestagswahl nicht abgeben können. Tausenden Auslandsdeutschen geht es genauso. Warum ich stocksauer bin. 👇👇👇
www.rnd.de/politik/bund...
www.rnd.de/politik/bund...
Warum ich erstmals in meinem Leben keine Wahl habe
Unser US-Korrespondent hat wie Tausende andere Auslandsdeutsche in den Vereinigten Staaten bis heute seine Briefwahlunterlagen nicht erhalten. Deshalb kann er seine Stimme bei der Bundestagswahl nicht...
www.rnd.de
February 19, 2025 at 6:56 PM
Aus. Vorbei. Zum ersten Mal in meinem Leben werde ich meine Stimme bei einer Bundestagswahl nicht abgeben können. Tausenden Auslandsdeutschen geht es genauso. Warum ich stocksauer bin. 👇👇👇
www.rnd.de/politik/bund...
www.rnd.de/politik/bund...