Director: MS in Neuroimaging and Informatics Program
MRI, amyloid & tau PET, Alzheimer's disease/ADRD.
metabolic/vascular risk, inflammation, health disparities, sex diff.
https://www.linkedin.com/in/meredith-braskie-1a3870321
We define PI-2620 tau PET cutpoints in a diverse cohort — summary of 🗝️ findings below ⬇️
675 adults:
• AB+ cognitively impaired (CI)
• AB– cognitively unimpaired (CU)
• 28% Hispanic, 31% NH Black, 41% NH White
🔗 Read it here:
(bit.ly/44RLVwe)
@victoriatennant.bsky.social
Looks at how amyloid, tau, & neurodegeneration vary by ethnoracial group & sex in Hispanic & non-Hispanic Black & White adults from HABS-HD.
Led by Dr. Michelle Caunca in Dr. Kristine Yaffe's lab.
Read here ➡️ bit.ly/4gUbwJi
@uscloni.bsky.social
Looks at how amyloid, tau, & neurodegeneration vary by ethnoracial group & sex in Hispanic & non-Hispanic Black & White adults from HABS-HD.
Led by Dr. Michelle Caunca in Dr. Kristine Yaffe's lab.
Read here ➡️ bit.ly/4gUbwJi
@uscloni.bsky.social
🔎Progression to MCI & dementia in 3 cohorts:
🧠Tau PET+ ➡️ faster cog decline.
🧠 50% of MCI patients ➡️ dementia in 2.36 years if amyloid+ & high tau at baseline.
Led by Lydia Trudel & Joseph Therriault
Dr. Pedro Rosa-Neto's lab
Read ➡️ bit.ly/46x3Byd
🔎Progression to MCI & dementia in 3 cohorts:
🧠Tau PET+ ➡️ faster cog decline.
🧠 50% of MCI patients ➡️ dementia in 2.36 years if amyloid+ & high tau at baseline.
Led by Lydia Trudel & Joseph Therriault
Dr. Pedro Rosa-Neto's lab
Read ➡️ bit.ly/46x3Byd
dx.doi.org/10.1002/alz....
➡️ Valuable resource for both researchers & clinicians!
➡️ ATNIV biomarkers, staging, connectomics & more
➡️ Plus: how are sex & country represented in first/last authorship?
@istaart.bsky.social Neuroimaging PIA
This year they’ll:
Train on state-of-the-art MRI
Explore computational modeling & big data
Collaborate with world-class faculty
Build skills to launch careers in neuroscience, medicine & industry✌️🧠
This year they’ll:
Train on state-of-the-art MRI
Explore computational modeling & big data
Collaborate with world-class faculty
Build skills to launch careers in neuroscience, medicine & industry✌️🧠
Methods & insights from the Health & Aging Brain Study – Health Disparities (HABS-HD) 🧠📊
We examine amyloid, tau, neurodegeneration, cognition & social determinants of health in Hispanic & NH Black & White older adults.
➡️ bit.ly/4mwp67J
@uscini.bsky.social
Methods & insights from the Health & Aging Brain Study – Health Disparities (HABS-HD) 🧠📊
We examine amyloid, tau, neurodegeneration, cognition & social determinants of health in Hispanic & NH Black & White older adults.
➡️ bit.ly/4mwp67J
@uscini.bsky.social
Can a drink of glucose change functional brain connectivity?
🥮+🧠= 🔎
"Default mode network connectivity responses to glucose ingestion in cognitively unimpaired older adults with and without type 2 diabetes"
@uscini.bsky.social
Can a drink of glucose change functional brain connectivity?
🥮+🧠= 🔎
"Default mode network connectivity responses to glucose ingestion in cognitively unimpaired older adults with and without type 2 diabetes"
@uscini.bsky.social
🧠APOE-ɛ4 moderates the association between HDL-c and white matter hyperintensity volume.
⏲️ 3:30 - 4:15 pm
@uscini.bsky.social
🧠APOE-ɛ4 moderates the association between HDL-c and white matter hyperintensity volume.
⏲️ 3:30 - 4:15 pm
@uscini.bsky.social
🧠 Session: Developing Topics on Tau Biomarkers
🕝 2:42–2:49 PM | 📍 Room 701
@uscini.bsky.social
🧠 Session: Developing Topics on Tau Biomarkers
🕝 2:42–2:49 PM | 📍 Room 701
@uscini.bsky.social
@uscini.bsky.social
@uscini.bsky.social
Excited to share our new research 🧠🧬
• Tau PET & genetic variants
• APOE, HDL, & WMH
• Longitudinal tau PET & inflammation
• DMN & glucose in aging & T2DM
See our full presentation lineup ⬇️
👋Come talk science with us!
Excited to share our new research 🧠🧬
• Tau PET & genetic variants
• APOE, HDL, & WMH
• Longitudinal tau PET & inflammation
• DMN & glucose in aging & T2DM
See our full presentation lineup ⬇️
👋Come talk science with us!
#ENDALZ
#ENDALZ
We define PI-2620 tau PET cutpoints in a diverse cohort — summary of 🗝️ findings below ⬇️
675 adults:
• AB+ cognitively impaired (CI)
• AB– cognitively unimpaired (CU)
• 28% Hispanic, 31% NH Black, 41% NH White
🔗 Read it here:
(bit.ly/44RLVwe)
@victoriatennant.bsky.social
We define PI-2620 tau PET cutpoints in a diverse cohort — summary of 🗝️ findings below ⬇️
675 adults:
• AB+ cognitively impaired (CI)
• AB– cognitively unimpaired (CU)
• 28% Hispanic, 31% NH Black, 41% NH White
🔗 Read it here:
(bit.ly/44RLVwe)
@victoriatennant.bsky.social
Establishing tau-PET cut-points for cognitive diagnosis with 18F-PI-2620 in a multi-ethnoracial cohort
doi.org/10.1162/IMAG...
Establishing tau-PET cut-points for cognitive diagnosis with 18F-PI-2620 in a multi-ethnoracial cohort
doi.org/10.1162/IMAG...
⭐️The ability of our tau cut points to distinguish cognitively impaired vs unimpaired people varied by ethnoracial group.
Learn more & check out the animation! bit.ly/45JfzER
⭐️The ability of our tau cut points to distinguish cognitively impaired vs unimpaired people varied by ethnoracial group.
We found that:
We found that:
-People with low resources & high distress had smaller hippocampi & thinner cortex in AD-relevant regions compared with people having more resources and less distress.
-Low resources (regardless of distress) were associated with accelerate brain aging.
-People with low resources & high distress had smaller hippocampi & thinner cortex in AD-relevant regions compared with people having more resources and less distress.
-Low resources (regardless of distress) were associated with accelerate brain aging.
We miss you already, Noelle!
We miss you already, Noelle!
-⬆️ light sleep% & longer REM sleep latency = thinner cortex in Alzheimer's disease-related regions
-⬆️ deep sleep % = thicker cortex (same regions)
-⬆️ apnea hypopnea index in rapid eye movement sleep = ⬆️ WMH volume.
-⬆️ light sleep% & longer REM sleep latency = thinner cortex in Alzheimer's disease-related regions
-⬆️ deep sleep % = thicker cortex (same regions)
-⬆️ apnea hypopnea index in rapid eye movement sleep = ⬆️ WMH volume.
Congrats NIIN graduates! So proud of you 🎉!
Congrats NIIN graduates! So proud of you 🎉!
Read more here: bit.ly/3GS0Ddj
More on our findings soon...
Learn more 👉 bit.ly/3GS0Ddj
Read more here: bit.ly/3GS0Ddj
More on our findings soon...
Winners:
1st: Kinder Bueno
2nd: Cadbury Dairy Milk
3rd: Beyond Good 73% Cocoa Salted Caramel (my fav)
The stats:
Milk chocolate fans: 5
Dark chocolate fans: 4
White chocolate fans: 1
Chocolate euphoria + spiking blood sugar: Everyone
Winners:
1st: Kinder Bueno
2nd: Cadbury Dairy Milk
3rd: Beyond Good 73% Cocoa Salted Caramel (my fav)
The stats:
Milk chocolate fans: 5
Dark chocolate fans: 4
White chocolate fans: 1
Chocolate euphoria + spiking blood sugar: Everyone