Mary-Elizabeth Jobson
@mejobson.bsky.social
PhD candidate in the Shaw Lab at the University of South Florida studying virulence factor regulation in S. aureus
Super excited to finally have this out! We characterized SSR42 as a novel RNA-based regulator of cytotoxicity in S. aureus. It is capable of responding to a host-like environment to activate the leukocidin LukAB and mediate neutriphil interactions. Check it out! journals.asm.org/doi/10.1128/...
SSR42 is a novel regulator of cytolytic activity in Staphylococcus aureus | mBio
Staphylococcus aureus is a master pathogen due to its formidable collection of virulence factors. These are tightly controlled by a diverse group of regulators that titrate their abundance to adapt to unique infectious niches. The role of regulatory RNAs ...
journals.asm.org
May 9, 2025 at 2:52 PM
Super excited to finally have this out! We characterized SSR42 as a novel RNA-based regulator of cytotoxicity in S. aureus. It is capable of responding to a host-like environment to activate the leukocidin LukAB and mediate neutriphil interactions. Check it out! journals.asm.org/doi/10.1128/...
So excited to be nearly there with my first first author paper! Talk to me about super long and cool regulatory RNAs that regulate toxin production in response to environmental stressors!
Our recent preprint on the regulatory RNA SSR42 in Staph. Wonderful to see the arc of this story, starting out with past lab members Andy Weiss & Brooke Tomlinson before @mejobson.bsky.social came along and made it her own. Hope to have this one over the line soon.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
SSR42 is a Novel Regulator of Cytolytic Activity in Staphylococcus aureus
SSR42 is the longest noncoding RNA in the S. aureus cell and the second-most abundant transcript in the stationary phase transcriptome, second only to RNAIII. It is highly conserved across strains and...
www.biorxiv.org
November 19, 2024 at 9:27 PM
So excited to be nearly there with my first first author paper! Talk to me about super long and cool regulatory RNAs that regulate toxin production in response to environmental stressors!