Marco Di Stefano
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mdistefano.bsky.social
Marco Di Stefano
@mdistefano.bsky.social
Italian 🇪🇺🇮🇹🏛 Happy husband 🇭🇳👩🏻‍⚕️& father👧 CNRS Researcher 👨‍💻💻🧬⚛️ @IGH_MTP🇫🇷/ex @Marciuslab🇪🇸 #4DGenome #biophys #epigen
Reposted by Marco Di Stefano
I found interesting :
-"Surprisingly, PRE looping does not require the PcG subunit Polyhomeotic (PH) or the repressive histone marks H3K27me3". They suggest: Looping specificity of Polycomb response elements requires GAF and a combinatorial code of looping factors.

www.biorxiv.org/content/10.1...
Looping specificity of Polycomb response elements requires GAF and a combinatorial code of looping factors
Chromatin looping between cis -regulatory elements is essential for precise developmental gene expression, and its disruption is frequently linked to disease. Polycomb Response Elements (PREs) are spe...
www.biorxiv.org
November 30, 2025 at 9:09 AM
Looping specificity of Polycomb response elements requires GAF and a combinatorial code of looping factors https://www.biorxiv.org/content/10.1101/2025.11.28.691166v1
December 2, 2025 at 4:14 PM