Matthew Kurian, MD
matthewkurianmd.bsky.social
Matthew Kurian, MD
@matthewkurianmd.bsky.social
Breast & Genitourinary Oncology at StElizabethNKY | Case Western Alum | Executive Board KYSCO | ASCOTECAG | cancerGRACE | Columnist at ASCO Connection | AI Enthusiast
Reposted by Matthew Kurian, MD
🔍 Does AI reduce #clinician workload?

@NEJM study on @NuanceDragon DAX Copilot, an AI-powered documentation tool, found minimal impact on EHR efficiency & financial metrics❗️

💡AI tools need to be developed in comjuction with 🩺🥼🧑‍⚕️ not in silos
#AIinMedicine #LLMs @oncoalert.bsky.social
December 21, 2024 at 5:17 AM
Reposted by Matthew Kurian, MD
Day 2 of OncLive News Network: On Location at #SABCS24 is ready for your viewing! Check out the #HER2 #bcsm updates from Drs Sara Hurvitz of @fredhutch.bsky.social & @neil-iyengarmd.bsky.social of @mskcancercenter.bsky.social hosted of course by Dr Chandler Park! www.onclive.com/view/unveili...
Unveiling the Latest in HER2+ Breast Cancer and Beyond With Drs Sara Hurvitz and Neil Iyengar
Sara Hurvitz, MD, of Fred Hutch Cancer Center, and Neil Iyengar, MD, of Memorial Sloan Kettering Cancer Center, sit down with Chandler Park, MD, FACP, to discuss the latest abstracts in breast cancer ...
www.onclive.com
December 12, 2024 at 9:51 PM
Fantastic event held yesterday by the @oncbrothers.bsky.social - truly thought provoking discussion with giants in the breast cancer space! Honored to be apart of it! @neil-iyengarmd.bsky.social @laurahuppert.bsky.so
@drsgraff.bsky.social
#sabcs2024 #signifymd
December 12, 2024 at 4:09 PM
Reposted by Matthew Kurian, MD
Wow! Median PFS was 44.3 months for pts treated with IBRANCE in combination with HP and endocrine therapy, and 29.1 months (95% CI: 23.3-38.6) for patients treated with HP and endocrine therapy alone [HR: 0.74 (95% CI, 0.58-0.94); p= 0.0074].

44 month first-line PFS!
@oncbrothers.bsky.social #SABCS
December 12, 2024 at 4:02 PM
Reposted by Matthew Kurian, MD
Congratulations to Dr. Ali for presenting @swog.org 0221 results at @sabcs.bsky.social @oncoalert.bsky.social @clevelandclinic.bsky.social
December 12, 2024 at 3:25 AM
Reposted by Matthew Kurian, MD
Great real world case discussion including #OSU @stoverlab.bsky.social @osuwexmed.bsky.social on the use of liquid biopsies in #mBC treatment decisions @sabcs.bsky.social #SABCS24 #bcsm Take Away - not ready for broad use in all pts, but may help in specific cases and holds promise for future
December 11, 2024 at 10:10 PM
Fantastic results from EMBER-3 showing response with abemaciclib + imlunestrant with ORR of 35% in combination for ESR1m HR+ adjuvant and ABC patients and specifically showed in those with ESR1m ⬆️PFS from 11.1m to 5.5m with combo vs oral SERD alone. #sabcs2024 @breastcancerdoc.bsky.social
December 11, 2024 at 5:13 PM
Reposted by Matthew Kurian, MD
EMBER3 now in @NEJM highlights imlunestrant is better than fulvestrant in mESR1 MBC, and combo of abema+ imlumnestrant is better independent of mutations in all

Presentation soon @sabcs.bsky.social #SABCS24 Congrats @breastcancerdoc.bsky.social et al!

www.nejm.org/doi/full/10....
Imlunestrant with or without Abemaciclib in Advanced Breast Cancer | NEJM
Imlunestrant is a next-generation, brain-penetrant, oral selective estrogen-receptor (ER) degrader that delivers continuous ER inhibition, even in cancers with mutations in the gene encoding ERα (E...
www.nejm.org
December 11, 2024 at 2:46 PM
Reposted by Matthew Kurian, MD
Dr. Dos Santos presents data around how the breast is changed during pregnancy...and persists (not just during pregnancy)! 🤰

May explain why parity and age impacts breast cancer risk 📊.

Early pregnancy ⬇️ breast cancer risk by 30-40%

#SABCS24
@sabcs.bsky.social
@oncoalert.bsky.social
#bcsm
December 10, 2024 at 10:19 PM
Need some simplification regarding ovarian suppression in premenopausal women? Nice summary by Prudence Francis from @petermaccc.bsky.social of who are candidates for OS + AI vs tamoxifen and timing of these agents is crucial! #sabcs2024
December 10, 2024 at 11:03 PM
Reposted by Matthew Kurian, MD
Planning your career after fellowship? Our article on ASCO connection explores the pros & cons of academia, community & hybrid practices! A practical guide to help fellows make informed decision! @matthewkurianmd.bsky.social Rajat Thawani!
December 10, 2024 at 4:15 AM
Reposted by Matthew Kurian, MD
Here at #SABCS24? Let’s discuss the current SoC & how the data will change/reinforce our practice from #SABCS24!

In Person, 📆: Dec11, 2024
⏰: 7:00-9:00PM
Register: bit.ly/aiosabcs24

#OncSky #AdvInOnc24 #bcsm
@drsarahsammons.bsky.social
@drgattimays.bsky.social
@drsgraff.bsky.social
December 10, 2024 at 12:23 AM
Reposted by Matthew Kurian, MD
RSclin for node positive ER+ patients is validated! I hope it’s available to use soon.

Always helpful to have tools to estimate recurrence and chemo benefit in these hard conversations with patients!

ascopubs.org/doi/10.1200/...
Development and Validation of the RSClinN+ Tool to Predict Prognosis and Chemotherapy Benefit for Hormone Receptor–Positive, Node-Positive Breast Cancer
PURPOSEClinicopathological factors and the 21-gene Oncotype DX Breast Recurrence Score (RS) test both influence prognosis. Our goal was to develop a new tool, RSClinN+, to individualize recurrence ris...
ascopubs.org
December 9, 2024 at 11:24 AM
Reposted by Matthew Kurian, MD
Dr. Abirami Natarajan and Dr. Sara Tolaney (@stolaney1.bsky.social) discuss adjuvant #ribociclib in this
Annals of Oncology editorial.
👀 check it out here:
sciencedirect.com/science/arti...
December 5, 2024 at 8:30 PM
Congrats to all who’ve matched into heme/onc fellowship! Beginning of an exciting journey! If you are a future or current fellow deciding your career trajectory check out my commentary with colleagues as we discuss the differences in practice settings!

connection.asco.org/do/navigatin...
Navigating Your Career Path After Fellowship: Pros and Cons of Different Oncology Practice Settings
connection.asco.org
December 6, 2024 at 10:11 PM
Reposted by Matthew Kurian, MD
An outstanding group for those who are looking for the #OncSky Cancer Care community of professionals here on BlueSky. @oncoalert.bsky.social @pallonccop.bsky.social

Starting a list of oncology related peopl. Please tell me more to add. Or any similar listd go.bsky.app/GKXp9Fy @n8pennell.bsky.social
December 1, 2024 at 10:00 AM
Reposted by Matthew Kurian, MD
Thanks for posting! A favorite activity is the recordings I do with Sara Tolaney around new data at our international meetings! @oncoalert.bsky.social @ucsfcancer.bsky.social
November 23, 2024 at 12:38 PM
Reposted by Matthew Kurian, MD
Good to see more and more organizations in alignment with starting at 40. Key point also is that everyone should be getting a breast cancer risk assessment starting at age 25 and reassessing periodically after to see if they are high risk and need earlier screening w additional modalities.
ACOG recommends starting mammography at age 40 for those at average breast cancer risk, due to a 2% annual increase in cases among women aged 40-49 from 2015 to 2019
#BreastCancer
ACOG recommends starting mammography at age 40 for those at average breast cancer risk, due to a 2% annual increase in cases among women aged 40-49 from 2015 to 2019. This update aligns with other major health organizations, advising continued screening every 1 to 2 years.

https://buff.ly/3UVMgJ0
November 21, 2024 at 6:08 PM
Reposted by Matthew Kurian, MD
Study in #JAMAOnc from Scotland/Wales of nearly 50k #breastcancer patients suggests vaginal estrogen use *NOT* associated w increase risk of breast cancer-specific mortality.

More reassuring data 👍

jamanetwork.com/journals/jam...
Vaginal Estrogen Therapy Use and Survival in Breast Cancer
This cohort study compares the mortality risk associated with vaginal estrogen therapy vs no hormone replacement therapy in 2 cohorts of patients with breast cancer in Scotland and Wales.
jamanetwork.com
November 23, 2024 at 2:28 PM
Reposted by Matthew Kurian, MD
Only 3 weeks to #SABCS24, a meeting that promises to significantly impact the way we treat breast cancer. It will feature phase 3 data with novel SERDs, novel ADCs, immunotherapy, ctDNA monitoring, important biomarker analyses & so much more. Here’s my top 10 abstracts list— see you in San Antonio!
November 17, 2024 at 8:01 PM